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Group Dr. Christian Kowol,


Prodrug Development, Drug Delivery Systems, Drug Targeting

 

Teaching link

CV

Publications

 

 

christian.kowol@univie.ac.at

Tel: +43 1 4277 52609

 

1090 Wien, Währinger Straße 42,
Halbstock, Zimmer 2H15, 

 

Research focus

Chemotherapy and therapy with small targeted molecules are two major strategies for treatment of human cancer at the disseminated stage. However, even when using new targeted drugs, the therapy is often limited by severe side effects, resistance development and insufficient tumor accumulation.

The research of my group focuses on the development of new strategies to overcome these limitations:

  • Bioinorganic prodrug development of clinically approved drugs to prevent the occurrence of severe side effects (for a press release click here
  • Drug delivery systems like nanoparticles, liposomes, polymers for tumor-specific accumulation and activation of anticancer drugs
  • Drug targeting strategies using tumor-specific peptides 

All research projects are highly interdisciplinary and are developed in close cooperation with the Institute of Cancer Research of the Medical University of Vienna within the Research Cluster “Translational Cancer Therapy Research”.

Awards

2016  Förderpreis of the Vienna Fund for Innovative Interdisciplinary Cancer Research for the publication “Tumor-Targeting of EGFR Inhibitors by Hypoxia-Mediated Activation"

2014   INiTS Award, 1st place for “Tumor-specific, Hypoxia-based Activation of EGFR-Inhibitors”

2014   RIZ GENIUS Award, 3rd place for “Tumor-specific Tyrosinkinase Inhibitors for Efficient Cancer Therapy”  

2011   Forschungsentwicklungspreis of the Vienna Fund for innovative interdisciplinary cancer research

2010   Bank Austria Award to support innovative research projects (Preis zur Förderung innovativer Forschungsprojekte)

International Collaborations

ANG, Wee Han National University Singapore (NUS), Singapore

ENYEDY, Éva Anna University of Szeged, Hungary

GALAMBA CORREIA, João University of Lisbon, Portugal

T E A M

Josef Mayr, MSc

 

Targeted Platinum(IV) Complexes

 

josef.mayr@univie.ac.at

Tel.:+43 1 4277 52665

 

1090 Wien, Währinger Straße 42,
1st Floor, Room 2112

Karla Pelivan, MSc.

 

Bio-Analytics


karla.pelivan@univie.ac.at

Tel.:+43 1 4277 52666

 

1090 Wien, Währinger Straße 42,
Halbstock, Room 2H14

Dipl.-Ing. Marlene Mathuber

 

Metal-based Anticancer Prodrugs

 

marlene.mathuber@univie.ac.at

Tel.:+43 1 4277 52616

 

1090 Wien, Währinger Straße 42,
Halbstock, Room 2H16

 

Sebastian Kallus, MSc

 

Liposomal Drug Formulations

 

sebastian.kallus@univie.ac.at

Tel.:+43 1 4277 52616

 

1090 Wien, Währinger Straße 42,
Halbstock, Room 2H16

Björn Bielec, MSc.

 

Anticancer Prodrugs 

 

bjoern.bielec@univie.ac.at

Tel.:+43 1 4277 52616

 

1090 Wien, Währinger Straße 42,
Halbstock, Room 2H16

Philipp Fronik, MSc MSc

 

Metal-based Anticancer prodrugs

 


philipp.fronik@univie.ac.at

 Tel: +43 1 4277 52616

1090 Wien, Währinger Straße 42,
Halbstock,  Room 2H16

Marianne Lahnsteiner

 

Anticancer Prodrugs

 

marianne.lahnsteiner@univie.ac.at

Tel.:+43 1 4277 52609

 

1090 Wien, Währinger Straße 42,
Halbstock, Room 2H19

Former Team Members