Publications Institute of Inorganic Chemistry


2013


Am(m)ines Make the Difference: Organoruthenium Am(m)ine Complexes and Their Chemistry in Anticancer Drug Development. / Babak, Maria; Meier, Samuel Matthias; Legin, Anton et al.
In: Chemistry: A European Journal, Vol. 19, No. 13, 2013, p. 4308-4318.

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Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs. / Hartinger, Christian G. (Corresponding author); Größl, Michael; Meier, Samuel Matthias et al.
In: Chemical Society Reviews, Vol. 42, No. 14, 2013, p. 6186-6199.

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Characterization of the binding sites of the anticancer ruthenium(III) complexes KP1019 and KP1339 on human serum albumin via competition studies. / Domotor, Orsolya; Hartinger, Christian G.; Bytzek, Anna et al.
In: Journal of Biological Inorganic Chemistry, Vol. 18, No. 1, 2013, p. 9-17.

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Copper(II) complexes with derivatives of pyrazole as potential antioxidant enzyme mimics. / Kupcewicz, Bogumila (Corresponding author); Sobiesiak, Krzysztof; Malinowska, Katarzyna et al.
In: Medicinal Chemistry Research: an international journal for rapid communications on design and mechanisms of action of biologically active agents, Vol. 22, No. 5, 2013, p. 2395-2402.

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Influence of extracellular pH on the cytotoxicity, cellular accumulation, and DNA interaction of novel pH-sensitive 2-aminoalcoholatoplatinum(II) complexes. / Valiahdi, Seied Mojtaba; Egger, Alexander; Miklos, Walter et al.
In: Journal of Biological Inorganic Chemistry, Vol. 18, No. 2, 2013, p. 249-260.

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Maleimide-functionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery. / Pichler, Verena; Mayr, Josef; Heffeter, Petra (Corresponding author) et al.
In: Chemical Communications, Vol. 49, No. 22, 2013, p. 2249-2251.

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Metal-Arene Complexes with Indolo[3,2-c]-quinolines: Effects of Ruthenium vs Osmium and Modifications of the Lactam Unit on Intermolecular Interactions, Anticancer Activity, Cell Cycle, and Cellular Accumulation. / Filak, Lukas; Göschl, Simone; Heffeter, Petra et al.
In: Organometallics, Vol. 32, No. 3, 2013, p. 903-914.

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Novel Metal(II)-Arene 2-Pyridinecarbothioamides: A Rationale to Orally Active Organometallic Anticancer Agents. / Meier, S. M.; Hanif, M.; Adhireksan, Z. et al.
In: Chemical Science, Vol. 4, No. 4, 2013, p. 1837-1846.

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Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity. / Kandioller, Wolfgang (Corresponding author); Balsano, Evelyn; Meier, Samuel Matthias et al.
In: Chemical Communications, Vol. 49, No. 32, 2013, p. 3348-3350.

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Osmium complexes with azole heterocycles as potential antitumor drugs in Encyclopedia of Metalloproteins. / Stepanenko, Iryna; Büchel, Gabriel; Keppler, Bernhard et al.
Encyclopedia of Metalloproteins. ed. / Robert H. Kretsinger; Vladimir N. Uversky; Eugene A. Permyakov. Springer New York LLC, 2013. p. 1696-1614.

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Striking Difference in Antiproliferative Activity of Ruthenium- and Osmium-Nitrosyl Complexes with Azole Heterocycles. / Büchel, Gabriel; Gavriluta, Anatolie; Novak, Maria et al.
In: Inorganic Chemistry, Vol. 52, No. 11, 2013, p. 6273-6285.

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Supergluing MOF liquid marbles. / Chin, Jia Min (Corresponding author); Reithofer, Michael R.; Tan, Tristan Tsai Yuan et al.
In: Chemical Communications, Vol. 49, No. 5, 2013, p. 493-495.

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Synergistic Anticancer Activity of Arsenic Trioxide with Erlotinib Is Based on Inhibition of EGFR-Mediated DNA Double-Strand Break Repair. / Kryeziu, Kushtrim; Jungwirth, Ute; Hoda, Mir Alireza et al.
In: Molecular Cancer Therapeutics, Vol. 12, No. 6, 2013, p. 1073-1084.

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Theoretical Investigations and Density Functional Theory Based Quantitative Structure-Activity Relationships Model for Novel Cytotoxic Platinum(IV) Complexes. / Varbanov, Hristo; Jakupec, Michael; Roller, Alexander et al.
In: Journal of Medicinal Chemistry, Vol. 56, No. 1, 2013, p. 330-344.

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X-ray Absorption Near Edge Structure Spectroscopy to Resolve the in Vivo Chemistry of the Redox-Active Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019). / Hummer, Alfred; Heffeter, Petra; Berger, Walter et al.
In: Journal of Medicinal Chemistry, Vol. 56, No. 3, 2013, p. 1182-1196.

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2012


Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma. / Rohr-Udilova, Nataliya; Sieghart, Wolfgang; Eferl, Robert et al.
In: Hepatology, Vol. 55, No. 4, 2012, p. 1112-1121.

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Anticancer Activity of Methyl-Substituted Oxaliplatin Analogs. / Jungwirth, Ute; Xanthos, Dimitris N.; Gojo, Johannes et al.
In: Molecular Pharmacology, Vol. 81, No. 5, 2012, p. 719-728.

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Application of ionic liquids for the removal of heavy metals from wastewater and activated sludge. / Fürhacker, Maria (Corresponding author); Haile, Tadele Measho; Kogelnig, Daniel et al.
In: Water Science and Technology, Vol. 65, No. 10, 2012, p. 1765-1773.

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A SAR Study of Novel Antiproliferative Ruthenium and Osmium Complexes with Quinoxalinone Ligands in Human Cancer Cell Lines. / Ginzinger, Werner; Mühlgassner, Gerhard; Arion, Vladimir (Corresponding author) et al.
In: Journal of Medicinal Chemistry, Vol. 55, No. 7, 2012, p. 3398-3413.

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Biological activity of ruthenium and osmium arene complexes with modified paullones in human cancer cells. / Mühlgassner, Gerhard; Bartel, Caroline; Schmid, Wolfgang et al.
In: Journal of Inorganic Biochemistry, Vol. 116, 2012, p. 180-187.

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Biomolecule binding vs. anticancer activity: Reactions of Ru(arene)[(thio)pyr-(id)one] compounds with amino acids and proteins. / Meier, Samuel Matthias; Kandioller, Wolfgang; Keppler, Bernhard et al.
In: Journal of Inorganic Biochemistry, Vol. 108, 2012, p. 91-95.

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Capillary zone electrophoresis and capillary zone electrophoresis-electrospray ionization mass spectrometry studies on the behavior of anticancer cis- and trans-[dihalidobis(2-propanone oxime)platinum(II)] complexes in aqueous solutions. / Grabmann, Gerlinde; Meier, Samuel Matthias; Scaffidi-Domianello, Yulia et al.
In: Journal of Chromatography A, Vol. 1267, No. SI, 2012, p. 156-161.

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Cellular accumulation and DNA interaction studies of cytotoxic trans-platinum anticancer compounds. / Bartel, Caroline; Bytzek, Anna; Scaffidi-Domianello, Yulia et al.
In: Journal of Biological Inorganic Chemistry, Vol. 17, No. 3, 2012, p. 465-474.

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Comparative solution equilibrium studies of anticancer gallium(III) complexes of 8-hydroxyquinoline and hydroxy(thio)pyrone ligands. / Enyedy, Eva Anna (Corresponding author); Domotor, Orsolya; Varga, Erika et al.
In: Journal of Inorganic Biochemistry, Vol. 117, 2012, p. 189-197.

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Complex-Formation Ability of Salicylaldehyde Thiosemicarbazone towards ZnII, CuII, FeII, FeIII and GaIII Ions. / Enyedy, Eva Anna (Corresponding author); Zsigo, Eva; Nagy, Nóra Veronika et al.
In: European Journal of Inorganic Chemistry, Vol. 25, 2012, p. 4036-4047.

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Diamminetetrakis(carboxylato)platinum(IV) Complexes - Synthesis, Characterization, and Cytotoxicity. / Hoffmeister, Björn; Adib Razavi, Mahsa Sadat; Jakupec, Michael et al.
In: Chemistry & Biodiversity, Vol. 9, No. 9, SI, 2012, p. 1840-1848.

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Effect of reactivity on cellular accumulation and cytotoxicity of oxaliplatin analogues. / Buss, Irina; Kalayda, Ganna V.; Lindauer, Andreas et al.
In: Journal of Biological Inorganic Chemistry, Vol. 17, No. 5, 2012, p. 699-708.

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Fragmentation methods on the balance: unambiguous top-down mass spectrometric characterization of oxaliplatin-ubiquitin binding sites. / Meier, Samuel Matthias; Tsybin, Yury O.; Dyson, Paul J. et al.
In: Analytical and Bioanalytical Chemistry, Vol. 402, No. 8, 2012, p. 2655-2662.

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Gallium compound GaQ3-induced Ca2+signalling triggers p53-dependent and -independent apoptosis in cancer cells. / Gogna, Rajan; Madan, Esha; Keppler, Bernhard et al.
In: British Journal of Pharmacology, Vol. 166, No. 2 SI, 2012, p. 617-636.

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Impact of terminal dimethylation on the resistance profile of alpha-N-heterocyclic thiosemicarbazones. / Heffeter, Petra; Pirker, Christine; Kowol, Christian et al.
In: Biochemical Pharmacology, Vol. 83, No. 12, 2012, p. 1623-1633.

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Ionic Liquids as Extracting Agents for Heavy Metals. / Stojanovic, Anja (Corresponding author); Keppler, Bernhard.
In: Separation Science and Technology (Philadelphia), Vol. 47, No. 2 SI, 2012, p. 189-203.

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L- and D-Proline Thiosemicarbazone Conjugates: Coordination Behavior in Solution and the Effect of Copper(II) Coordination on Their Antiproliferative Activity. / Milunovic, Miljan; Enyedy, Eva Anna (Corresponding author); Nagy, Nóra Veronika et al.
In: Inorganic Chemistry, Vol. 51, No. 17, 2012, p. 9309-9321.

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Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules. / Nazarov, Alexey A.; Legin, Anton; Größl, Michael et al.
In: Chemical Communications, Vol. 48, No. 10, 2012, p. 1475-1477.

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Mechanisms underlying reductant-induced reactive oxygen species formation by anticancer copper(II) compounds. / Kowol, Christian; Heffeter, Petra; Miklos, Walter et al.
In: Journal of Biological Inorganic Chemistry, Vol. 17, No. 3, 2012, p. 409-423.

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Nanoscale lignin particles as sources of dissolved iron to the ocean. / Krachler, Regina (Corresponding author); von der Kammer, Frank; Jirsa, Franz et al.
In: Global Biogeochemical Cycles: an international journal of global change, Vol. 26, 2012.

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Nanoscalic silver possesses broad-spectrum antimicrobial activities and exhibits fewer toxicological side effects than silver sulfadiazine. / Brandt, Oliver (Corresponding author); Mildner, Michael; Egger, Alexander et al.
In: Nanomedicine - Nanotechnology Biology and Medicine, Vol. 8, No. 4, 2012, p. 478-488.

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Novel Oximato-Bridged Platinum(II) Di- and Trimer(s): Synthetic, Structural, and in Vitro Anticancer Activity Studies. / Scaffidi-Domianello, Yulia; Legin, Anton; Jakupec, Michael et al.
In: Inorganic Chemistry, Vol. 51, No. 13, 2012, p. 7153-7163.

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Novel tetracarboxylatoplatinum(IV) complexes as carboplatin prodrugs. / Varbanov, Hristo; Valiahdi, Seied Mojtaba; Kowol, Christian et al.
In: Dalton Transactions, Vol. 41, No. 47, 2012, p. 14404-14415.

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Organometallic Ruthenium and Osmium Compounds of Pyridin-2-and-4-ones as Potential Anticancer Agents. / Kandioller, Wolfgang; Hanif, Muhammad; Keppler, Bernhard et al.
In: Chemistry & Biodiversity, Vol. 9, No. 9, SI, 2012, p. 1718-1727.

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Osmium(IV) complexes with 1H- and 2H-indazoles: Tautomer identity versus spectroscopic properties and antiproliferative activity. / Büchel, Gabriel; Stepanenko, Iryna; Hejl, Michaela et al.
In: Journal of Inorganic Biochemistry, Vol. 113, 2012, p. 47-54.

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Ruthenium- and osmium-arene-based paullones bearing a TEMPO free-radical unit as potential anticancer drugs. / Arion, Vladimir (Corresponding author); Dobrov, Anatolie; Göschl, Simone et al.
In: Chemical Communications, Vol. 48, No. 68, 2012, p. 8559-8561.

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Ruthenium- and osmium-arene complexes of 8-substituted indolo[3,2-c] quinolines: Synthesis, X-ray diffraction structures, spectroscopic properties, and antiproliferative activity. / Filak, Lukas; Göschl, Simone; Hackl, Stefanie et al.
In: Inorganica Chimica Acta, Vol. 393, 2012, p. 252-260.

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Solid-phase synthesis of oxaliplatin-TAT peptide bioconjugates. / Abramkin, Sergey; Valiahdi, Seied Mojtaba; Jakupec, Michael et al.
In: Dalton Transactions, Vol. 41, No. 10, 2012, p. 3001-3005.

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Solid State Structural Variations in Copper(II) Complexes of Open-Chain and Macrocyclic Malonamide-Derived Ligands. / Gavrish, Sergey P.; Lampeka, Yaroslav D. (Corresponding author); Lightfoot, Philip et al.
In: Crystal Growth & Design, Vol. 12, No. 9, 2012, p. 4388-4396.

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Structure-Activity Relationships of Targeted Ru-II(eta(6)-p-Cymene) Anticancer Complexes with Flavonol-Derived Ligands. / Kurzwernhart, Andrea; Kandioller, Wolfgang; Bächler, Simone et al.
In: Journal of Medicinal Chemistry, Vol. 55, No. 23, 2012, p. 10512-10522.

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Synthesis and Biological Evaluation of the Thionated Antibacterial Agent Nalidixic Acid and Its Organoruthenium(II) Complex. / Hudej, Rosana; Kljun, Jakob; Kandioller, Wolfgang et al.
In: Organometallics, Vol. 31, No. 16, 2012, p. 5867-5874.

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Targeting the DNA-topoisomerase complex in a double-strike approach with a topoisomerase inhibiting moiety and covalent DNA binder. / Kurzwernhart, Andrea; Kandioller, Wolfgang; Bartel, Caroline et al.
In: Chemical Communications, Vol. 48, No. 40, 2012, p. 4839-4841.

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Unsymmetric mono- and dinuclear platinum(IV) complexes featuring an ethylene glycol moiety: Synthesis, characterization, and biological activity. / Pichler, Verena; Heffeter, Petra; Valiahdi, Seied Mojtaba et al.
In: Journal of Medicinal Chemistry, Vol. 55, No. 24, 2012, p. 11052-11061.

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Water-Soluble Cationic Derivatives of Indirubin, the Active Anticancer Component from Indigo naturalis. / Ginzinger, Werner; Egger, Alexander; Mühlgassner, Gerhard et al.
In: Chemistry & Biodiversity, Vol. 9, No. 10, 2012, p. 2175-2185.

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X-ray Absorption Spectroscopy of an Investigational Anticancer Gallium(III) Drug: Interaction with Serum Proteins, Elemental Distribution Pattern, and Coordination of the Compound in Tissue. / Hummer, Alfred; Bartel, Caroline; Arion, Vladimir et al.
In: Journal of Medicinal Chemistry, Vol. 55, No. 11, 2012, p. 5601-5613.

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