Publications Institute of Inorganic Chemistry


2008


Unprecedented twofold intramolecular hydroamination in diam(m)ine- dicarboxylatodichloridoplatinum(IV) complexes - ethane-1,2-diamine vs. ammine ligands. / Reithofer, Michael; Galanski, Mathea Sophia; Arion, Vladimir et al.
In: Chemical Communications, No. 9, 2008, p. 1091-1093.

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Water-soluble mixed-ligand ruthenium(II) and osmium(II) arene complexes with high antiproliferative activity. / Schuecker, Raffael; John, Roland; Jakupec, Michael et al.
In: Organometallics, Vol. 27, 2008, p. 6587-6595.

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2007


18F fluoroethylations: different strategies for the rapid translation of 11C-methylated radiotracers. / Wadsak, Wolfgang; Mien, Leonhard-Key; Ettlinger, Dagmar E. et al.
In: Nuclear Medicine and Biology, Vol. 34, No. 8, 2007, p. 1019-1028.

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A glucose derivative as natural alternative of the cyclohexane-1,2-diamine ligand in the anticancer drug oxaliplatin? / Nazarov, Alexey (Corresponding author); Keppler, Bernhard (Corresponding author); Berger, Isabella et al.
In: ChemMedChem: chemistry enabling drug discovery, Vol. 2, No. 4, 2007, p. 505-514.

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Application of micellar and microemulsion electrokinetic chromatography for characterization of gallium (III) complexes of pharmaceutical significance. / Timerbaev, Andrei; Vasylenko, O O; Foteeva, Lidia S. et al.
In: Journal of Separation Science, Vol. 30, No. 3, 2007, p. 399-406.

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Capillary electrophoresis of metal-based drugs. / Timerbaev, Andrei; Keppler, Bernhard.
In: Analytical Biochemistry, Vol. 369, No. 1, 2007, p. 1-7.

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CE in anticancer metallodrug research - An update. / Hartinger, Christian; Keppler, Bernhard.
In: Electrophoresis, Vol. 28, No. 19, 2007, p. 3436-3446.

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Characterization of interactions between human serum albumin and tumor-inhibiting amino alcohol platinum(II) complexes using capillary electrophoresis. / Aleksenko, Svetlana S.; Hartinger, Christian; Semenova, Olga et al.
In: Journal of Chromatography A, Vol. 1155, No. 2, 2007, p. 218-221.

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Editorial: Anticancer Platinum Complexes - State of the Art and Future Prospects. / Galanski, Mathea Sophia.
In: Anti-Cancer Agents in Medicinal Chemistry, Vol. 7, No. 1, 2007, p. 1-2.

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Effect of metal ion complexation and chalcogen donor identity on the antiproliferative activity of 2-acetylpyridine N,N-dimethyl(chalcogen)semicarbazones. / Keppler, Bernhard (Corresponding author); Arion, Vladimir (Corresponding author); Kowol, Christian et al.
In: Journal of Inorganic Biochemistry, Vol. 101, No. 12, 2007, p. 1946-1957.

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First example of the solid-state thermal cyclometalation of ligated benzophenone imine giving novel luminescent platinum(II) species. / Scaffidi-Domianello, Yulia; Nazarov, Alexey; Haukka, M et al.
In: Inorganic Chemistry, Vol. 46, No. 11, 2007, p. 4469-4482.

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Gallium(III) and iron(III) complexes of alpha-N-heterocyclic thiosemicarbazones: Synthesis, characterization, cytotoxicity, and interaction with ribonucleotide reductase. / Kowol, Christian; Berger, Roland; Eichinger, Rene et al.
In: Journal of Medicinal Chemistry, Vol. 50, No. 6, 2007, p. 1254-1265.

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Highly Antiproliferative Ruthenium(II) and Osmium(II) Arene Complexes with Paullone-Derived Ligands. / Keppler, Bernhard (Corresponding author); Arion, Vladimir (Corresponding author); Schmid, Wolfgang et al.
In: Organometallics, Vol. 26, No. 26, 2007, p. 6643-6652.

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Mass spectrometric analysis of ubiquitin-platinum interactions of leading anticancer drugs: MALDI versus ESI. / Hartinger, Christian; Ang, Wee Han; Casini, Angela et al.
In: Journal of Analytical Atomic Spectrometry, Vol. 22, No. 8, 2007, p. 960-967.

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Metal-based Paullones as putative CDK inhibitors for antitumor chemotherapy. / Schmid, Wolfgang; John, Roland; Mühlgassner, Gerhard et al.
In: Journal of Medicinal Chemistry, Vol. 50, No. 25, 2007, p. 6343-6355.

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Multidrug-resistant cancer cells are preferential targets of the new antineoplastic lanthanum compound KP772 (FFC24). / Heffeter, Petra; Jakupec, Michael; Körner, Wilfried et al.
In: Biochemical Pharmacology, Vol. 73, No. 12, 2007, p. 1873-1886.

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Nanoparticle for the diagnosis of vascular disease [Nanopartikel zur Diagnose von Blutgefäßerkrankungen]. / Kundu, Amitava; Keppler, Bernhard.
In: Nachrichten aus der Chemie, Vol. 55, No. 9, 2007, p. 842-846.

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Novel di- and tetracarboxylatoplatinum(IV) complexes. Synthesis, characterization, cytotoxic activity, and DNA platination. / Reithofer, Michael; Valiahdi, Seied Mojtaba; Jakupec, Michael et al.
In: Journal of Medicinal Chemistry, Vol. 50, No. 26, 2007, p. 6692-6699.

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Osmium NAMI-a analogues: Synthesis, structural and spectroscopic characterization, and antiproliferative properties. / Keppler, Bernhard (Corresponding author); Cebrian, Berta; Krokhin, Artem et al.
In: Inorganic Chemistry, Vol. 46, No. 12, 2007, p. 5023-5033.

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Probing the stability of serum protein-ruthenium(III) drug adducts in the presence of extracellular reductants using CE. / Timerbaev, Andrei; Foteeva, Lidia S.; Rudnev, Alexander V. et al.
In: Electrophoresis, Vol. 28, No. 13, 2007, p. 2235-2240.

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Reversion of structure-activity relationships of antitumor platinum complexes by acetoxime but not hydroxylamine ligands. / Zorbas-Seifried, Stefanie; Jakupec, Michael; Kukushkin, Nikolay et al.
In: Molecular Pharmacology, Vol. 71, No. 1, 2007, p. 357-365.

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Ruthenium(II) complexes of thiosemicarbazones: The first water-soluble complex with pH-dependent antiproliferative activity. / Arion, Vladimir (Corresponding author); Keppler, Bernhard (Corresponding author); Grguric-Sipka, Sanja et al.
In: European Journal of Inorganic Chemistry, Vol. 2007, No. 18, 2007, p. 2870-2878.

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Searching for the magic bullet: Anticancer platinum drugs which can be accumulated or activated in the tumor tissue. / Galanski, Mathea Sophia; Keppler, Bernhard.
In: Anti-Cancer Agents in Medicinal Chemistry, Vol. 7, No. 1, 2007, p. 55-73.

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Species specific IDMS for accurate quantification of carboplatin in urine by LC-ESI-TOFMS and LC-ICP-QMS. / Köllensperger, Gunda; Stefánka, Zsolt; Meelich, Kristof et al.
In: Journal of Analytical Atomic Spectrometry, 2007.

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Synthesis, structure, protolytic properties, alkylating and cytotoxic activity of novel platinum(II) and palladium(II) complexes with pyrazole-derived ligands. / Budzisz, Elzbieta; Malecka, Magdalena; Keppler, Bernhard et al.
In: European Journal of Inorganic Chemistry, No. 23, 2007, p. 3728-3735.

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The complexes [OsCl2(azole)2(dmso)2] and [OsCl2(azole)(dmso)3]: Synthesis, structure, spectroscopic properties and catalytic hydration of chloronitriles. / Stepanenko, Iryna; Cebrian, Berta; Arion, Vladimir et al.
In: European Journal of Inorganic Chemistry, No. 3, 2007, p. 400-411.

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The First Ruthenium-Based Paullones: Syntheses, X-ray Diffraction Structures, and Spectroscopic and Antiproliferative Properties in Vitro. / Schmid, Wolfgang; Zorbas-Seifried, Stefanie; John, Roland et al.
In: Inorganic Chemistry, Vol. 46, No. 9, 2007, p. 3645-3656.

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Two new "onium" fluorosilicates, the products of interaction of fluorosilicic acid with 12-membered macrocycles: Structures and spectroscopic properties. / Gelmboldt, Vladimir O.; Fonari, Marina S.; Simonov, Yurii A. et al.
In: Dalton Transactions, Vol. 27, 2007, p. 2915-2924.

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2006


An Entry to Novel Platinum Complexes. Carboxylation of Dihydroxoplatinum(IV) Complexes with Succinic Anhydride and Subsequent Derivatization. / Reithofer, Michael; Galanski, Mathea Sophia (Corresponding author); Roller, Alexander et al.
In: European Journal of Inorganic Chemistry, No. 13, 2006, p. 2612-2617.

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Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)] trithiocyanate (KP772; FFC24). / Heffeter, Petra; Jakupec, Michael; Körner, Wilfried et al.
In: Biochemical Pharmacology, Vol. 71, No. 4, 2006, p. 426-440.

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Bis(2-amino alcohol-κN)dicarboxylatoplatinum(II) complexes - Elegant synthesis via ring-opening of bis(2-amino alcoholato-κ2N,O) platinum(II) species with dicarboxylic acids. / Meelich, Kristof; Galanski, Mathea Sophia (Corresponding author); Arion, Vladimir et al.
In: European Journal of Inorganic Chemistry, No. 12, 2006, p. 2476-2483.

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Crystal structure of trans-dichloro(dimethylsulfoxide)(diphenylsulfimide)- platinum(II) toluene hemisolvate, PtCl2(C2H 6SO)(C12H10SNH) ž 1/2C7H 8. / Scaffidi-Domianello, Yulia; Haukka, M; Kelly, Paul F et al.
In: Zeitschrift für Kristallographie - New Crystal Structures, Vol. 221, No. 2, 2006, p. 226-228.

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Determination of cisplatin and its hydrolytic metabolite in human serum by capillary electrophoresis techniques. / Huang, Zhuo; Timerbaev, Andrei; Keppler, Bernhard et al.
In: Journal of Chromatography A, Vol. 1106, No. 1-2, 2006, p. 75-79.

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DNA interactions of pH-sensitive, antitumor bis(aminoalcohol) dichloroplatinum(II) complexes. / Zorbas-Seifried, Stefanie; Hartinger, Christian; Meelich, Kristof et al.
In: Biochemistry, Vol. 45, No. 49, 2006, p. 14817-14825.

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Electrospray ionization mass spectrometric study on the coordination behavior of dacarbazine towards transition metal ions. / Hartinger, Christian; Mendoza Parra Ferri, Maria Grazia; Nazarov, Alexey et al.
In: Polyhedron, Vol. 25, No. 9, 2006, p. 1971-1978.

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From bench to bedside - preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A). / Hartinger, Christian; Zorbas-Seifried, Stefanie; Jakupec, Michael et al.
In: Journal of Inorganic Biochemistry, Vol. 100, No. 5-6, 2006, p. 894-904.

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Interactions of antitumor metallodrugs with serum proteins: Advances in characterization using modern analytical methodology. / Timerbaev, Andrei; Hartinger, Christian (Corresponding author); Aleksenko, Svetlana S. et al.
In: Chemical Reviews, Vol. 106, No. 6, 2006, p. 2224-2248.

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Kinetic and Thermodynamic Aspects of the Regioselective Addition of Bifunctional Hydroxylaminooxime-type HO-Nucleophiles to Pt-Complexed Nitriles. / Luzyanin, Konstantin V.; Kukushkin, Vadim Yu; Kuznetsov, Maxim L. et al.
In: Inorganic Chemistry, Vol. 45, No. 5, 2006, p. 2296-2306.

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Metallodrug research and analysis using capillary electrophoresis. / Timerbaev, Andrei; Hartinger, Christian; Keppler, Bernhard.
In: Trends in Analytical Chemistry, Vol. 25, No. 9, 2006, p. 868-875.

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NCA nucleophilic radiofluorination on substituted benzaldehydes for the preparation of [18F]fluorinated aromatic amino acids. / Wadsak, Wolfgang; Wirl-Sagadin, Barbara; Mitterhauser, Markus et al.
In: Applied Radiation and Isotopes, Vol. 64, No. 3, 2006, p. 355-359.

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Platinum group metallodrug-protein binding studies by capillary electrophoresis-inductively coupled plasma-mass spectrometry: a further insight into the reactivity of a novel antitumor ruthenium(III) complex toward human serum proteins. / Polec-Pawlak, Katarzyna; Abramski, Jan K.; Semenova, Olga et al.
In: Electrophoresis, Vol. 27, No. 5-6, 2006, p. 1128-1135.

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Preclinical characterization of anticancer gallium(III) complexes: solubility, stability, lipophilicity and binding to serum proteins. / Timerbaev, Andrei (Corresponding author); Rudnev, Alexander V.; Foteeva, Lidia S. et al.
In: Journal of Inorganic Biochemistry, Vol. 100, No. 11, 2006, p. 1819-1826.

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Recent developments in the field of anticancer platinum complexes. / Galanski, Mathea Sophia (Corresponding author).
In: Recent Patents on Anti-Cancer Drug Discovery, Vol. 1, No. 2, 2006, p. 285-295.

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Redox behavior of tumor-inhibiting ruthenium(III) complexes and effects of physiological reductants on their binding to GMP. / Schluga, Petra; Hartinger, Christian (Corresponding author); Egger, Alexander et al.
In: Dalton Transactions, Vol. 14, 2006, p. 1796-1802.

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Signal separation and determination of the enantiomeric purity of primary amines with (-)-myrtenal - a 13C NMR study. / Dufrasne, Francois; Gelbcke, Michael; Galanski, Mathea Sophia.
In: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Vol. 65, No. 3-4, 2006, p. 869-873.

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Synthesis and characterization of [(1R,2R)-trans-diaminocyclohexane]- platinum(II) coordinated to sulfur and selenium amino acids. / Rothenburger, Claudia; Galanski, Mathea Sophia (Corresponding author); Arion, Vladimir et al.
In: European Journal of Inorganic Chemistry, No. 18, 2006, p. 3746-3752.

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The First Metal-Based Paullone Derivative with High Antiproliferative Activity in Vitro. / Dobrov, Anatolie; Arion, Vladimir (Corresponding author); Kandler, Norbert et al.
In: Inorganic Chemistry, Vol. 45, No. 5, 2006, p. 1945-1950.

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Tris(8-quinolinolato)gallium(III) exerts strong antiproliferative effects in melanoma cells. / Valiahdi, Seied Mojtaba; Jakupec, Michael; Marculescu, Rodrig et al.
Metal Ions in Biology and Medicin. Unknown publisher, 2006. p. 282-286.

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Tumorhemmende Metallverbindungen. / Galanski, Mathea Sophia; Keppler, Bernhard.
In: Pharmazie in Unserer Zeit, Vol. 35, No. 2, 2006, p. 118-123.

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