Publications Institute of Inorganic Chemistry


2015


Tetracarboxylatoplatinum(IV) complexes featuring monodentate leaving groups - A rational approach toward exploiting the platinum(IV) prodrug strategy. / Hoefer, Doris; Varbanov, Hristo P. (Corresponding author); Legin, Anton et al.
In: Journal of Inorganic Biochemistry, Vol. 153, 12.2015, p. 259-271.

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The rearrangement of tosylated flavones to 1 '-(alkylamino)aurones with primary amines. / Kandioller, Wolfgang; Kubanik, Mario; Bytzek, Anna K. et al.
In: Tetrahedron, Vol. 71, No. 47, 25.11.2015, p. 8953-8959.

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Comparative solution equilibrium studies on pentamethylcyclopentadienyl rhodium complexes of 2,2 '-bipyridine and ethylenediamine and their interaction with human serum albumin. / Enyedy, Eva A. (Corresponding author); Meszaros, Janos P.; Doemoetoer, Orsolya et al.
In: Journal of Inorganic Biochemistry, Vol. 152, 11.2015, p. 93-103.

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Vanadium(IV/V) complexes of Triapine and related thiosemicarbazones: Synthesis, solution equilibrium and bioactivity. / Kowol, Christian R. (Corresponding author); Nagy, Nora V.; Jakusch, Tamas et al.
In: Journal of Inorganic Biochemistry, Vol. 152, 11.2015, p. 62-73.

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Proteomic and Metabolomic Analyses Reveal Contrasting Anti-Inflammatory Effects of an Extract of Mucor Racemosus Secondary Metabolites Compared to Dexamethasone. / Meier, Samuel M.; Muqaku, Besnik; Ullmann, Ronald et al.
In: PLoS ONE, Vol. 10, No. 10, e0140367, 23.10.2015.

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Heteropentanuclear Oxalato-Bridged nd-4f (n=4, 5) Metal Complexes with NO Ligand: Synthesis, Crystal Structures, Aqueous Stability and Antiproliferative Activity. / Kuhn, Paul-Steffen; Cremer, Laura; Gavriluta, Anatolie et al.
In: Chemistry: A European Journal, Vol. 21, No. 39, 21.09.2015, p. 13703-13713.

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Speciation of metal-based nanomaterials in human serum characterized by capillary electrophoresis coupled to ICP-MS: a case study of gold nanoparticles. / Matczuk, Magdalena; Anecka, Karolina; Scaletti, Federica et al.
In: Metallomics: integrated biometal science, Vol. 7, No. 9, 01.09.2015, p. 1364-1370.

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River-derived humic substances as iron chelators in seawater. / Krachler, Regina (Corresponding author); Krachler, Rudolf F.; Wallner, Gabriele et al.
In: Marine Chemistry, Vol. 174, 20.08.2015, p. 85-93.

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Tumor microenvironment in focus: LA-ICP-MS bioimaging of a preclinical tumor model upon treatment with platinum(IV)-based anticancer agents. / Theiner, Sarah; Kornauth, Christoph; Varbanov, Hristo P. et al.
In: Metallomics: integrated biometal science, Vol. 7, No. 8, 01.08.2015, p. 1256-1264.

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Three-dimensional and co-culture models for preclinical evaluation of metal-based anticancer drugs. / Schreiber-Brynzak, Ekaterina; Klapproth, Erik; Unger, Christine et al.
In: Investigational New Drugs: the journal of new anti-cancer agents, Vol. 33, No. 4, 08.2015, p. 835-847.

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Synthesis and bioactivity of a conjugate composed of green tea catechins and hyaluronic acid. / Lee, Fan; Lim, Jaehong; Reithofer, Michael R. et al.
In: Polymer chemistry, Vol. 6, No. 24, 28.06.2015, p. 4462-4472.

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Non-Close-Packed Breath Figures via Ion-Partitioning-Mediated Self-Assembly. / Aw, Jia En; Goh, Glen Tai Wei; Huang, Shengnan et al.
In: Langmuir, Vol. 31, No. 24, 23.06.2015, p. 6688-6694.

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Combination of Cadmium and High Cholesterol Levels as a Risk Factor for Heart Fibrosis. / Tuerkcan, Adrian; Scharinger, Bernhard; Grabmann, Gerlinde et al.
In: Toxicological Sciences, Vol. 145, No. 2, 06.2015, p. 360-371.

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Complexes of N-hydroxyethyl-N-benzimidazolylmethylethylenediaminediacetic acid with group 12 metals and vanadium-Synthesis, structure and bioactivity of the vanadium complex. / Habala, Ladislav; Bartel, Caroline; Giester, Gerald et al.
In: Journal of Inorganic Biochemistry, Vol. 147, 06.2015, p. 147-152.

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Triapine-mediated ABCB1 induction via PKC induces widespread therapy unresponsiveness but is not underlying acquired triapine resistance. / Miklos, W.; Pelivan, K.; Kowol, C. R. et al.
In: Cancer Letters, Vol. 361, No. 1, 28.05.2015, p. 112-120.

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Organometallic complexes of (thio)allomaltol-based Mannich-products: Synthesis, stability and preliminary biological investigations. / Schmidlehner, Melanie; Pichler, Verena; Roller, Alexander et al.
In: Journal of Organometallic Chemistry, Vol. 782, 15.04.2015, p. 69-76.

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Bis- and Tetrakis(carboxylato)platinum(IV) Complexes with Mixed Axial Ligands - Synthesis, Characterization, and Cytotoxicity. / Hoffmeister, Bjoern R.; Hejl, Michaela; Adib-Razavi, Mahsa S. et al.
In: Chemistry & Biodiversity, Vol. 12, No. 4, 04.2015, p. 559-574.

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Bis- and Tris(carboxylato)platinum(IV) Complexes with Mixed Am(m)ine Ligands in the trans Position Exhibiting Exceptionally High Cytotoxicity. / Hoffmeister, Bjoern R.; Hejl, Michaela; Jakupec, Michael A. et al.
In: European Journal of Inorganic Chemistry, Vol. 2015, No. 10, 04.2015, p. 1700-1708.

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Half-Sandwich Ruthenium(II) Biotin Conjugates as Biological Vectors to Cancer Cells. / Babak, Maria V.; Plazuk, Damian; Meier, Samuel M. et al.
In: Chemistry: A European Journal, Vol. 21, No. 13, 23.03.2015, p. 5110-5117.

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1,3-Dioxoindan-2-carboxamides as Bioactive Ligand Scaffolds for the Development of Novel Organometallic Anticancer Drugs. / Mokesch, Stephan; Novak, Maria S.; Roller, Alexander et al.
In: Organometallics, Vol. 34, No. 5, 09.03.2015, p. 848-857.

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Extravasation of Pt-based chemotherapeutics - bioimaging of their distribution in resectates using laser ablation-inductively coupled plasma-mass spectrometry ( LA-ICP-MS). / Egger, Alexander E.; Kornauth, Christoph; Haslik, Werner et al.
In: Metallomics: integrated biometal science, Vol. 7, No. 3, 01.03.2015, p. 508-515.

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Extraction of natural radionuclides from aqueous solutions by novel maltolate-based task-specific ionic liquids. / Platzer, Sonja; Sap, Orhan; Leyma, Raphlin et al.
In: Journal of Radioanalytical and Nuclear Chemistry, Vol. 303, No. 3, 03.2015, p. 2483-2488.

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Comparative in vitro and in vivo pharmacological investigation of platinum(IV) complexes as novel anticancer drug candidates for oral application. / Theiner, Sarah; Varbanov, Hristo P.; Galanski, Mathea Sophia et al.
In: Journal of Biological Inorganic Chemistry, Vol. 20, No. 1, 01.2015, p. 89-99.

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Interaction of the anticancer gallium(III) complexes of 8-hydroxyquinoline and maltol with human serum proteins. / Enyedy, Eva A. (Corresponding author); Doemoetoer, Orsolya; Bali, Krisztina et al.
In: Journal of Biological Inorganic Chemistry, Vol. 20, No. 1, 01.2015, p. 77-88.

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DNA Methylation Analysis of Genes Playing a Role in Multidrug Resistance. / Kaltenbrunner, Maria; Spitzwieser, Melanie; Heffeter, Petra et al.
In: Acta Medica Marisiensis, Vol. 61, No. Suppl. 5, 2015, p. 30.

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Expanding on the Structural Diversity of Flavone- Derived Ruthenium II ( ƞ 6 -arene) Anticancer Agents. / Kubanik, Mario; Tu, Jason K. Y. ; Söhnel, Tilo et al.
In: Metallodrugs, Vol. 1, 2015, p. 24-35.

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Improved reaction conditions for the synthesis of new NKP-1339 derivatives and preliminary investigations on their anticancer potential. / Kuhn, P. -S.; Pichler, V.; Roller, A. et al.
In: Dalton Transactions, Vol. 44, No. 2, 2015, p. 659-668.

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Influence of reducing agents on the cytotoxic activity of platinum(IV) complexes: induction of G(2)/M arrest, apoptosis and oxidative stress in A2780 and cisplatin resistant A2780cis cell lines. / Pichler, Verena; Goeschl, Simone; Schreiber-Brynzak, Ekaterina et al.
In: Metallomics: integrated biometal science, Vol. 7, No. 7, 2015, p. 1078-1090.

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Protein ruthenation and DNA alkylation: chlorambucil-functionalized RAPTA complexes and their anticancer activity. / Nazarov, Alexey A. (Corresponding author); Meier, Samuel M.; Zava, Olivier et al.
In: Dalton Transactions, Vol. 44, No. 8, 2015, p. 3614-3623.

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Solution equilibria and antitumor activities of pentamethylcyclopentadienyl rhodium complexes of picolinic acid and deferiprone. / Enyedy, Eva A. (Corresponding author); Doemoetoer, Orsolya; Hackl, Carmen M. et al.
In: Journal of Coordination Chemistry, Vol. 68, No. 9, 2015, p. 1583-1601.

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Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action. / Babak, Maria V.; Meier, Samuel M.; Huber, Kilian V. M. et al.
In: Chemical Science, Vol. 6, No. 4, 2015, p. 2449-2456.

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2014


New method for the speciation of ruthenium-based chemotherapeutics in human serum by conjoint liquid chromatography on affinity and anion-exchange monolithic disks. / Martincic, Anze; Milacic, Radmila; Vidmar, Janja et al.
In: Journal of Chromatography A, Vol. 1371, 05.12.2014, p. 168-176.

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Microwave-assisted synthesis of N-heterocycle-based organometallics. / Schmidlehner, Melanie; Kuhn, Paul-Steffen; Hackl, Carmen M. et al.
In: Journal of Organometallic Chemistry, Vol. 772, 01.12.2014, p. 93-99.

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Modulation of Activity of Known Cytotoxic Ruthenium(III) Compound (KP418) with Hampered Transmembrane Transport in Electrochemotherapy In Vitro and In Vivo. / Hudej, Rosana; Miklavcic, Damijan; Cemazar, Maja et al.
In: Journal of Membrane Biology, Vol. 247, No. 12, 12.2014, p. 1239-1251.

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Tumor-Targeting of EGFR Inhibitors by Hypoxia-Mediated Activation. / Karnthaler-Benbakka, Claudia; Groza, Diana; Kryeziu, Kushtrim et al.
In: Angewandte Chemie (International Edition), Vol. 53, No. 47, 17.11.2014, p. 12930-12935.

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Motorized Janus metal organic framework crystals. / Tan, Tristan T.Y.; Cham, Jerald T.M.; Reithofer, Michael R. et al.
In: Chemical Communications, Vol. 50, No. 96, 06.11.2014, p. 15175-15178.

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{Ru(CO)(x)}-core complexes with selected azoles: Synthesis, X-ray structure, spectroscopy, DFT analysis and evaluation of cytotoxic activity against human cancer cells. / Tamasi, Gabriella (Corresponding author); Carpini, Alice; Valensin, Daniela et al.
In: Polyhedron, Vol. 81, 15.10.2014, p. 227-237.

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Calpain-mediated integrin deregulation as a novel mode of action for the anticancer gallium compound KP46. / Jungwirth, Ute; Gojo, Johannes; Tuder, Theresa et al.
In: Molecular Cancer Therapeutics, Vol. 13, No. 10, 10.2014, p. 2436-2449.

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Quantitative bioimaging by LA-ICP-MS: a methodological study on the distribution of Pt and Ru in viscera originating from cisplatin- and KP1339-treated mice. / Egger, Alexander E. (Corresponding author); Theiner, Sarah; Kornauth, Christoph et al.
In: Metallomics: integrated biometal science, Vol. 6, No. 9, 09.2014, p. 1616-1625.

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A Novel Class of Bis- and Tris-Chelate Diam(m)inebis(dicarboxylato)platinum(IV) Complexes as Potential Anticancer Prodrugs. / Varbanov, Hristo P. (Corresponding author); Goeschl, Simone; Heffeter, Petra et al.
In: Journal of Medicinal Chemistry, Vol. 57, No. 15, 14.08.2014, p. 6751-6764.

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Inductively coupled plasma mass spectrometry for metallodrug development: Albumin binding and serum distribution of cytotoxic cis- and trans-isomeric platinum(II) complexes. / Ossipov, Konstantin; Scaffidi-Domianello, Yulia Y.; Seregina, Irina F. et al.
In: Journal of Inorganic Biochemistry, Vol. 137, 08.2014, p. 40-45.

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In situ synthesis of size-controlled, stable silver nanoparticles within ultrashort peptide hydrogels and their anti-bacterial properties. / Reithofer, Michael R.; Lakshmanan, Anupama; Ping, Andy T.K. et al.
In: Biomaterials, Vol. 35, No. 26, 08.2014, p. 7535-7542.

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Total Mercury in Sediments, Macrophytes, and Fish from a Shallow Steppe Lake in Eastern Austria. / Jirsa, Franz (Corresponding author); Pirker, Daniel; Krachler, Regina et al.
In: Chemistry & Biodiversity, Vol. 11, No. 8, 08.2014, p. 1263-1275.

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Efficiently Detecting Metallodrug-Protein Adducts: Ion Trap versus Time-of-Flight Mass Analyzers. / Meier, Samuel M.; Babak, Maria V.; Keppler, Bernhard K. et al.
In: ChemMedChem: chemistry enabling drug discovery, Vol. 9, No. 7, 07.2014, p. 1351-1355.

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Enhanced Anticancer Activity and Circumvention of Resistance Mechanisms by Novel Polymeric/Phospholipidic Nanocarriers of Doxorubicin. / Senkiv, Y.; Riabtseva, A.; Heffeter, P. et al.
In: Journal of Biomedical Nanotechnology, Vol. 10, No. 7, 07.2014, p. 1369-1381.

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NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application. / Trondl, Robert; Heffeter, Petra; Kowol, Christian R. et al.
In: Chemical Science, Vol. 5, No. 8, 30.06.2014, p. 2925-2932.

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Can neutral analytes be concentrated by transient isotachophoresis in micellar electrokinetic chromatography and how much? / Matczuk, Magdalena; Foteeva, Lidia S.; Jarosz, Maciej et al.
In: Journal of Chromatography A, Vol. 1345, 06.06.2014, p. 212-218.

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Ruthenium II6-arene) complexes of thiourea derivatives: Synthesis, Characterization and Urease Inhibition. / Hanif, Muhammad (Corresponding author); Nawaz, Muhammad Azhar Hayat; Babak, Maria V. et al.
In: Molecules, Vol. 19, No. 6, 06.2014, p. 8080-8092.

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Antitumor pentamethylcyclopentadienyl rhodium complexes of maltol and allomaltol: Synthesis, solution speciation and bioactivity. / Doemoetoer, Orsolya; Aicher, Sabine; Schmidlehner, Melanie et al.
In: Journal of Inorganic Biochemistry, Vol. 134, 05.2014, p. 57-65.

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Nanoformulation Improves Activity of the (pre)Clinical Anticancer Ruthenium Complex KP1019. / Heffeter, P.; Riabtseva, A.; Senkiv, Y. et al.
In: Journal of Biomedical Nanotechnology, Vol. 10, No. 5, 05.2014, p. 877-884.

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