Publications Institute of Inorganic Chemistry


2014


Nanoformulation Improves Activity of the (pre)Clinical Anticancer Ruthenium Complex KP1019. / Heffeter, P.; Riabtseva, A.; Senkiv, Y. et al.
In: Journal of Biomedical Nanotechnology, Vol. 10, No. 5, 05.2014, p. 877-884.

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Photoresponsive liquid marbles and dry water. / Tan, Tristan Tsai Yuan; Ahsan, Aniq; Reithofer, Michael R. et al.
In: Langmuir, Vol. 30, No. 12, 01.04.2014, p. 3448-3454.

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Guanidine platinum(II) complexes: synthesis, in vitro antitumor activity, and DNA interactions*. / Legin, Anton A.; Jakupec, Michael A. (Corresponding author); Bokach, Nadezhda A. et al.
In: Journal of Inorganic Biochemistry, Vol. 133, 04.2014, p. 33-39.

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Ruthenium-Nitrosyl Complexes with Glycine, L-Alanine, L-Valine, L-Proline, D-Proline, L-Serine, L-Threonine, and L-Tyrosine: Synthesis, X-ray Diffraction Structures, Spectroscopic and Electrochemical Properties, and Antiproliferative Activity. / Rathgeb, Anna; Boehm, Andreas; Novak, Maria S. et al.
In: Inorganic Chemistry, Vol. 53, No. 5, 03.03.2014, p. 2718-2729.

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Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells. / Trondl, Robert; Flocke, Lea S.; Kowol, Christian R. et al.
In: Molecular Pharmacology, Vol. 85, No. 3, 03.2014, p. 451-459.

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Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy. / Reithofer, Michael R. (Corresponding author); Chan, Kiat Hwa; Lakshmanan, Anupama et al.
In: Chemical Science, Vol. 5, No. 2, 02.2014, p. 625-630.

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Solution equilibrium studies of anticancer ruthenium(II)-η 6- p-cymene complexes of pyridinecarboxylic acids. / Sija, Eva; Hartinger, Christian G.; Keppler, Bernhard K. et al.
In: Polyhedron, Vol. 67, 08.01.2014, p. 51-58.

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Platinum(IV) Complexes Featuring One or Two Axial Ferrocene Bearing Ligands - Synthesis, Characterization, and Cytotoxicity. / Banfic, Jelena; Legin, Anton A.; Jakupec, Michael A. et al.
In: European Journal of Inorganic Chemistry, Vol. 2014, No. 3, 01.2014, p. 484-492.

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Aqueous chemistry and antiproliferative activity of a pyrone-based phosphoramidate Ru(arene) anticancer agent. / Meier, Samuel M.; Novak, Maria S.; Kandioller, Wolfgang et al.
In: Dalton Transactions, Vol. 43, No. 26, 2014, p. 9851-9855.

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Poly(lactic acid) nanoparticles of the lead anticancer ruthenium compound KP1019 and its surfactant-mediated activation. / Fischer, Britta; Heffeter, Petra; Kryeziu, Kushtrim et al.
In: Dalton Transactions, Vol. 43, No. 3, 2014, p. 1096-1104.

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2013


Tuning omniphobicity via morphological control of metal-organic framework functionalized surfaces. / Tan, Tristan T.Y.; Reithofer, Michael R.; Chen, Eric Y. et al.
In: Journal of the American Chemical Society, Vol. 135, No. 44, 06.11.2013, p. 16272-16275.

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Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexes. / Hanif, Muhammad; Meier, Samuel Matthias; Nazarov, Alexey A. et al.
In: Frontiers in Chemistry, Vol. 1, 27, 31.10.2013.

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Solution equilibria of anticancer ruthenium(II)-(eta(6)-p-cymene)-hydroxy(thio)pyr(id) one complexes: Impact of sulfur vs. oxygen donor systems on the speciation and bioactivity. / Enyedy, Eva A.; Sija, Eva; Jakusch, Tamas (Corresponding author) et al.
In: Journal of Inorganic Biochemistry, Vol. 127, 10.2013, p. 161-168.

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The ruthenium compound KP1339 potentiates the anticancer activity of sorafenib in vitro and in vivo. / Heffeter, Petra; Atil, Bihter; Kryeziu, Kushtrim et al.
In: European Journal of Cancer, Vol. 49, No. 15, 10.2013, p. 3366-3375.

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New ruthenium(II)-arene complexes bearing hydrazides and the corresponding (thio)semicarbazones of 3-and 4-acetylpyridine: Synthesis, characterization, crystal structure determination and antiproliferative activity. / Ivanovic, Ivanka; Gligorijevic, Nevenka; Arandelovic, Sandra et al.
In: Polyhedron, Vol. 61, 18.09.2013, p. 112-118.

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Dicopper(II) and Dizinc(II) Complexes with Nonsymmetric Dinucleating Ligands Based on Indolo[3,2-c]quinolines: Synthesis, Structure, Cytotoxicity, and Intracellular Distribution. / Primik, Michael F.; Goeschl, Simone; Meier, Samuel M. et al.
In: Inorganic Chemistry, Vol. 52, No. 17, 02.09.2013, p. 10137-10146.

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p53 Increases Intra-Cellular Calcium Release by Transcriptional Regulation of Calcium Channel TRPC6 in GaQ(3)-Treated Cancer Cells. / Madan, Esha; Gogna, Rajan (Corresponding author); Keppler, Bernhard et al.
In: PLoS ONE, Vol. 8, No. 8, 71016, 16.08.2013.

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A systematic capillary electrophoresis study on the effect of the buffer composition on the reactivity of the anticancer drug cisplatin to the DNA model 2 '-deoxyguanosine 5'-monophosphate (dGMP). / Grabmann, Gerlinde; Keppler, Bernhard K.; Hartinger, Christian G. (Corresponding author).
In: Analytical and Bioanalytical Chemistry, Vol. 405, No. 20, 08.2013, p. 6417-6424.

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Synthesis of cyclic carbonates with carbon dioxide and cesium carbonate. / Reithofer, Michael R.; Sum, Yin Ngai; Zhang, Yugen (Corresponding author).
In: Green Chemistry, Vol. 15, No. 8, 08.2013, p. 2086-2090.

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Bulky N(,N)-(Di)alkylethane-1,2-diamineplatinum(II) Compounds as Precursors for Generating Unsymmetrically Substituted Platinum(IV) Complexes. / Pichler, Verena; Goeschl, Simone; Meier, Samuel M. et al.
In: Inorganic Chemistry, Vol. 52, No. 14, 15.07.2013, p. 8151-8162.

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Identification of the Structural Determinants for Anticancer Activity of a Ruthenium Arene Peptide Conjugate. / Meier, Samuel M.; Novak, Maria; Kandioller, Wolfgang et al.
In: Chemistry: A European Journal, Vol. 19, No. 28, 08.07.2013, p. 9297-9307.

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Influence of metal salts on the hydrogelation properties of ultrashort aliphatic peptides. / Mishra, Archana; Chan, Kiat Hwa; Reithofer, Michael R. et al.
In: RSC Advances , Vol. 3, No. 25, 07.07.2013, p. 9985-9993.

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Osmium-nitrosyl complexes with glycine, picolinic acid, L -proline and D -proline: Synthesis, structures and antiproliferative activity. / Gavriluta, A.; Novak, M.; Tommasino, J.B. et al.
In: Zeitschrift für Anorganische und Allgemeine Chemie, Vol. 639, No. 8-9, 01.07.2013, p. 1590-1597.

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Platinum(IV) Complexes Featuring Axial (1,4-C-13(2))Succinato Ligands - Synthesis, Characterization, and Preliminary Investigations in Cancer Cell Lysates. / Banfic, Jelena; Adib Razavi, Mahsa Sadat; Galanski, Mathea Sophia (Corresponding author) et al.
In: Zeitschrift für Anorganische und Allgemeine Chemie, Vol. 639, No. 8-9, 07.2013, p. 1613-1620.

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Rhodium(Cp*) Compounds with Flavone-derived Ligand Systems: Synthesis and Characterization. / Schwarz, Martina B.; Kurzwernhart, Andrea; Roller, Alexander et al.
In: Zeitschrift für Anorganische und Allgemeine Chemie, Vol. 639, No. 8-9, 07.2013, p. 1648-1654.

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Natural organic matter and iron export from the Tanner Moor, Austria. / Jirsa, Franz (Corresponding author); Neubauer, Elisabeth; Kittinger, Richard et al.
In: Limnologica, Vol. 43, No. 4, 01.06.2013, p. 239-244.

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Monoaryloxide Pyrrolide (MAP) Imido Alkylidene Complexes of Molybdenum and Tungsten That Contain 2,6-Bis(2,5-R-2-pyrrolyl)phenoxide (R = i-Pr, Ph) Ligands and an Unsubstituted Metallacyclobutane on Its Way to Losing Ethylene. / Reithofer, Michael R.; Dobereiner, Graham E.; Schrock, Richard R. (Corresponding author) et al.
In: Organometallics, Vol. 32, No. 9, 13.05.2013, p. 2489-2492.

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3-Hydroxyflavones vs. 3-hydroxyquinolinones: structure-activity relationships and stability studies on Ru-II(arene) anticancer complexes with biologically active ligands. / Kurzwernhart, Andrea; Kandioller, Wolfgang; Enyedy, Eva Anna et al.
In: Dalton Transactions, Vol. 42, No. 17, 2013, p. 6193-6202.

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A highly cytotoxic modified paullone ligand bearing a TEMPO free-radical unit and its copper(II) complex as potential hR2 RNR inhibitors. / Dobrov, Anatolie; Goeschl, Simone; Jakupec, Michael A. et al.
In: Chemical Communications, Vol. 49, No. 85, 2013, p. 10007-10009.

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Am(m)ines Make the Difference: Organoruthenium Am(m)ine Complexes and Their Chemistry in Anticancer Drug Development. / Babak, Maria; Meier, Samuel Matthias; Legin, Anton et al.
In: Chemistry: A European Journal, Vol. 19, No. 13, 2013, p. 4308-4318.

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Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs. / Hartinger, Christian G. (Corresponding author); Größl, Michael; Meier, Samuel Matthias et al.
In: Chemical Society Reviews, Vol. 42, No. 14, 2013, p. 6186-6199.

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Characterization of the binding sites of the anticancer ruthenium(III) complexes KP1019 and KP1339 on human serum albumin via competition studies. / Domotor, Orsolya; Hartinger, Christian G.; Bytzek, Anna et al.
In: Journal of Biological Inorganic Chemistry, Vol. 18, No. 1, 2013, p. 9-17.

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Copper(II) complexes with derivatives of pyrazole as potential antioxidant enzyme mimics. / Kupcewicz, Bogumila (Corresponding author); Sobiesiak, Krzysztof; Malinowska, Katarzyna et al.
In: Medicinal Chemistry Research: an international journal for rapid communications on design and mechanisms of action of biologically active agents, Vol. 22, No. 5, 2013, p. 2395-2402.

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Influence of extracellular pH on the cytotoxicity, cellular accumulation, and DNA interaction of novel pH-sensitive 2-aminoalcoholatoplatinum(II) complexes. / Valiahdi, Seied Mojtaba; Egger, Alexander; Miklos, Walter et al.
In: Journal of Biological Inorganic Chemistry, Vol. 18, No. 2, 2013, p. 249-260.

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Maleimide-functionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery. / Pichler, Verena; Mayr, Josef; Heffeter, Petra (Corresponding author) et al.
In: Chemical Communications, Vol. 49, No. 22, 2013, p. 2249-2251.

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Metal-Arene Complexes with Indolo[3,2-c]-quinolines: Effects of Ruthenium vs Osmium and Modifications of the Lactam Unit on Intermolecular Interactions, Anticancer Activity, Cell Cycle, and Cellular Accumulation. / Filak, Lukas; Göschl, Simone; Heffeter, Petra et al.
In: Organometallics, Vol. 32, No. 3, 2013, p. 903-914.

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Novel Metal(II)-Arene 2-Pyridinecarbothioamides: A Rationale to Orally Active Organometallic Anticancer Agents. / Meier, S. M.; Hanif, M.; Adhireksan, Z. et al.
In: Chemical Science, Vol. 4, No. 4, 2013, p. 1837-1846.

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Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity. / Kandioller, Wolfgang (Corresponding author); Balsano, Evelyn; Meier, Samuel Matthias et al.
In: Chemical Communications, Vol. 49, No. 32, 2013, p. 3348-3350.

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Osmium complexes with azole heterocycles as potential antitumor drugs in Encyclopedia of Metalloproteins. / Stepanenko, Iryna; Büchel, Gabriel; Keppler, Bernhard et al.
Encyclopedia of Metalloproteins. ed. / Robert H. Kretsinger; Vladimir N. Uversky; Eugene A. Permyakov. Springer New York LLC, 2013. p. 1696-1614.

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Striking Difference in Antiproliferative Activity of Ruthenium- and Osmium-Nitrosyl Complexes with Azole Heterocycles. / Büchel, Gabriel; Gavriluta, Anatolie; Novak, Maria et al.
In: Inorganic Chemistry, Vol. 52, No. 11, 2013, p. 6273-6285.

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Supergluing MOF liquid marbles. / Chin, Jia Min (Corresponding author); Reithofer, Michael R.; Tan, Tristan Tsai Yuan et al.
In: Chemical Communications, Vol. 49, No. 5, 2013, p. 493-495.

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Synergistic Anticancer Activity of Arsenic Trioxide with Erlotinib Is Based on Inhibition of EGFR-Mediated DNA Double-Strand Break Repair. / Kryeziu, Kushtrim; Jungwirth, Ute; Hoda, Mir Alireza et al.
In: Molecular Cancer Therapeutics, Vol. 12, No. 6, 2013, p. 1073-1084.

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Theoretical Investigations and Density Functional Theory Based Quantitative Structure-Activity Relationships Model for Novel Cytotoxic Platinum(IV) Complexes. / Varbanov, Hristo; Jakupec, Michael; Roller, Alexander et al.
In: Journal of Medicinal Chemistry, Vol. 56, No. 1, 2013, p. 330-344.

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X-ray Absorption Near Edge Structure Spectroscopy to Resolve the in Vivo Chemistry of the Redox-Active Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019). / Hummer, Alfred; Heffeter, Petra; Berger, Walter et al.
In: Journal of Medicinal Chemistry, Vol. 56, No. 3, 2013, p. 1182-1196.

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2012


Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma. / Rohr-Udilova, Nataliya; Sieghart, Wolfgang; Eferl, Robert et al.
In: Hepatology, Vol. 55, No. 4, 2012, p. 1112-1121.

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Anticancer Activity of Methyl-Substituted Oxaliplatin Analogs. / Jungwirth, Ute; Xanthos, Dimitris N.; Gojo, Johannes et al.
In: Molecular Pharmacology, Vol. 81, No. 5, 2012, p. 719-728.

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Application of ionic liquids for the removal of heavy metals from wastewater and activated sludge. / Fürhacker, Maria (Corresponding author); Haile, Tadele Measho; Kogelnig, Daniel et al.
In: Water Science and Technology, Vol. 65, No. 10, 2012, p. 1765-1773.

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A SAR Study of Novel Antiproliferative Ruthenium and Osmium Complexes with Quinoxalinone Ligands in Human Cancer Cell Lines. / Ginzinger, Werner; Mühlgassner, Gerhard; Arion, Vladimir (Corresponding author) et al.
In: Journal of Medicinal Chemistry, Vol. 55, No. 7, 2012, p. 3398-3413.

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Biological activity of ruthenium and osmium arene complexes with modified paullones in human cancer cells. / Mühlgassner, Gerhard; Bartel, Caroline; Schmid, Wolfgang et al.
In: Journal of Inorganic Biochemistry, Vol. 116, 2012, p. 180-187.

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