Publications 2018


Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA
Kiakos, K., Englinger, B., Yanow, S. K., Wernitznig, D., Jakupec, M. A., Berger, W., Keppler, B. K., Hartley, J. A., Lee, M. & Patil, P. C.
Bioorganic & Medicinal Chemistry Letters (2018) 28, 8, 1342-1347

The impact of whole human blood on the kinetic inertness of platinum(IV) prodrugs - an HPLC-ICP-MS study
Theiner, S., Grabarics, M., Galvez, L., Varbanov, H. P., Sommerfeld, N. S., Galanski, M., Keppler, B. K. & Koellensperger
Dalton Transactions (Print Edition) (2018) 47, 15, 5252-5258

N- and S-donor leaving groups in triazole-based ruthena(II) cycles: potent anticancer activity, selective activation, and mode of action studies
Riedl, C. A., Hejl, M., Klose, M. H. M., Roller, A., Jakupec, M. A., Kandioller, W. & Keppler, B. K.
Dalton Transactions (Print Edition) (2018) 47, 13, 4625-4638

α-Arylamino Diazoketones: Diazomethane-Loading Controlled Synthesis, Spectroscopic Investigations and Structural X-ray Analysis
Castoldi, L., Ielo, L., Holzer, W., Giester, G., Roller, A. & Pace, V.
The Journal of Organic Chemistry (2018) 83, 8, 4336-4347

Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action
Babak, M. V., Pfaffeneder-Kmen, M., Meier-Menches, S. M., Legina, M. S., Theiner, S., Licona, C., Orvain, C., Hejl, M., Hanif, M., Jakupec, M. A., Keppler, B. K., Gaiddon, C. & Hartinger, C. G.
Inorganic Chemistry (2018) 57, 5, 2851-2864

A comparative study of alpha-N-pyridyl thiosemicarbazones: Spectroscopic properties, solution stability and copper(II) complexation
Domotor, O., May, N. V., Pelivan, K., Kiss, T., Keppler, B. K., Kowol, C. R. & Enyedy, E. A.
Inorganica Chimica Acta (2018) 472, 264-275

Bioimaging of isosteric osmium and ruthenium anticancer agents by LA-ICP-MS
Klose, M. H. M., Theiner, S., Kornauth, C., Meier-Menches, S. M., Heffeter, P., Berger, W., Koellensperger, G. & Keppler, B. K.
Metallomics (2018) 10, 3, 388-396

Complexes of pyridoxal thiosemicarbazones formed with vanadium(IV/V) and copper(II): Solution equilibrium and structure
Jakusch, T., Kozma, K., Enyedy, E. A., May, N. V., Roller, A., Kowol, C. R., Keppler, B. K. & Kiss, T.
Inorganica Chimica Acta (2018) 472, 243-253

Comparison of metabolic pathways of different alpha-N-heterocyclic thiosemicarbazones
Pelivan, K., Frensemeier, L. M., Karst, U., Koellensperger, G., Heffeter, P., Keppler, B. K. & Kowol, C. R.
Analytical and Bioanalytical Chemistry (2018) 410, 9, 2343-2361

[F-18]FEPPA: Improved Automated Radiosynthesis, Binding Affinity, and Preliminary in Vitro Evaluation in Colorectal Cancer
Berroteran-Infante, N., Balher, T., Fuerlinger, P., Bergmann, M., Lanzenberger, R., Hacker, M., Mitterhauser, M. & Wadsak, W.
Bioorganic & Medicinal Chemistry Letters (2018) 9, 3, 177-181

The advanced glycation end product N-epsilon-carboxymethyllysine and its precursor glyoxal increase serotonin release from Caco-2 cells
Holik, A-K., Lieder, B., Kretschy, N., Somoza, M. M., Ley, J. P., Hans, J. & Somoza, V.
Journal of Cellular Biochemistry (2018) 119, 3, 2731-2741

Anticancer Thiosemicarbazones: Chemical Properties, Interaction with Iron Metabolism, and Resistance Development
Heffeter, P., Pape, V. F. S., Enyedy, E. A., Keppler, B. K., Szakacs, G. & Kowol, C. R.
Antioxidants and Redox Signaling (2018)

Structure-activity relationships for ruthenium and osmium anticancer agents - towards clinical development
Meier-Menches, S. M., Gerner, C., Berger, W., Hartinger, C. G. & Keppler, B. K.
Chemical Society Reviews (2018) 47, 3, 909-928

Palladium Complexes of N,N '-Bis(2-aminoethyl)oxamide (H2L): Structural ((PL)-L-II, (Pd2L2)-L-II, and (PdLCl2)-L-IV), Electrochemical, Dynamic H-1 NMR, and Cytotoxicity Studies
Gavrish, S. P., Lampeka, Y. D., Babak, M. V. & Arion, V. B.
Inorganic Chemistry (2018) 57, 3, 1288-1297

Speed matters to raise molar radioactivity: Fast HPLC shortens the quality control of C-11 PET-tracers
Nics, L., Steiner, B., Klebermass, E-M., Philippe, C., Mitterhauser, M., Hacker, M. & Wadsak, W.
Nuclear Medicine and Biology (2018) 57, 28-33

Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis
Groza, D., Gehrig, S., Kudela, P., Holcmann, M., Pirker, C., Dinhof, C., Schueffl, H. H., Sramko, M., Hoebart, J., Alioglu, F., Grusch, M., Ogris, M., Lubitz, W., Keppler, B. K., Pashkunova-Martic, I., Kowol, C. R., Sibilia, M., Berger, W. & Heffeter, P.
OncoImmunology (2018) 7, 5, 1424676

Expanding LogP: Present possibilities
Vraka, C., Mijailovic, S., Fröhlich, V., Zeilinger, M., Klebermass, E-M., Wadsak, W., Wagner, K-H., Hacker, M. & Mitterhauser, M.
Nuclear Medicine and Biology (2018) 58, 20-32

Studies of KP46 and KP1019 and the Hydrolysis Product of KP1019 in Lipiodol Emulsions: Preparation and Initial Characterizations as Potential Theragnostic Agents

Pashkunova-Martic, I., Cebrian Losantos, B., Kandler, N. & Keppler, B.
Current Drug Delivery (2018) 15, 1, 134 - 142

On the Tautomerism of N-Substituted Pyrazolones: 1,2-Dihydro-3H-pyrazol-3-ones versus 1H-Pyrazol-3-ols
Arbaciauskiene, E., Krikstolaityte, S., Mitruleviciene, A., Bieliauskas, A., Martynaitis, V., Bechmann, M., Roller, A., Sackus, A. & Holzer, W.
Molecules (2018) 23, 1, 129