Dipl.-Ing. Dr. Wolfgang Kandioller, Senior Scientist
Phone: +43-1-4277-52609
Email: wolfgang.kandioller@univie.ac.at
Währinger Straße 42, Room 2H15
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Research Focus
The research of my group focuses on the following topics for the development of organometallic anticancer agents to overcome the drawbacks of clinically approved platinum-based drugs:
- Influence of different coordination motifs and organometallic moieties on the anticancer potential
- Exploiting bioactive ligand scaffolds to design novel metallodrugs with improved anticancer activities
- Determining the impact of leaving group variation on the physicochemical and biological properties
Team
Alexander Rosner, BSc MSc
Improving the anticancer potency of tridentate naphthoquinone-derived organometallics
Phone: +43-1-4277-52616
Email: alexander.rosner@univie.ac.at
Währinger Straße 42, Room: 2H16
Dipl.-Ing. Paul Getreuer, BSc
Impact of different coordination motifs on the anticancer potential of organometallic complexes
Phone: +43-1-4277-52616
Email: paul.getreuer@univie.ac.at
Währinger Straße 42, Room: 2H16
Paul Thrakl, BSc
Phone: +43-1-4277-52616
Email: paul.thrakl@univie.ac.at
Währinger Straße 42, Room: 2H16
Andreas Diridl, BSc
Währinger Straße 42, Room: 2H16
Julia Stöllinger, BSc
Währinger Straße 42, Room: 2H16
Former Team Members
- Heiko Geisler (Master's and PhD student)
Development of phthiocol-based organometallics with anticancer properties
Ligand and metal center variation of 2-hydroxy-3-methyl-[1,4]-naphthoquinone-based organometallics - Sophia Harringer (PhD student)
Lead structure optimization for the development of organometallic anticancer drugs - Christoph Riedl (Master's and PhD student)
Investigations on different coordination motifs for the development of novel organometallic anticancer agents
1,4-disubstituted 1,2,3-triazoles as novel ligand scaffold for the development of organometallic anticancer agents - Stephan Mokesch (Master's and PhD student)
The development of novel anticancer agents with bioactive molecules attached to organometallic fragments
1,3-Dioxoindan-2-carboxamides as selective O,O-chelating ligands for the development of novel organometallic anticancer drugs - Carmen Hackl (Master's and PhD student)
Leaving-group variation of "piano-stool" complexes for the development of novel organometallic anticancer drugs with targeting properties
The impact of metal variation of the anticancer activity of thiopyrone-derived complexes - Barbara Happl (Master's student)
Thiopyridone-based organorhodium and -iridium complexes: synthesis, characterization and behavior in aqueous solution - Manuel Matzinger (Master's student)
Establishing selenopyrones as novel ligand scaffold for organometallic anticancer agents - Marius Ozenil (Master's student)
Ru and Os thiopyridone complexes and their instant hydrolysis to thiolato-bridged dimers in aqueous solution - Melanie Schmidlehner (PhD student)
Synthesis, characterization and anticancer activity of metal complexes with (thio)pyrone-derived ligands - Marlene Reikersdorfer (Master's student)
The impact of leaving group variation on the anticancer activity of molybdenocene-based complexes