Publications 2014
u:cris
New method for the speciation of ruthenium-based chemotherapeutics in human serum by conjoint liquid chromatography on affinity and anion-exchange monolithic disks
Martincic, A., Milacic, R., Vidmar, J., Turel, I., Keppler, B. K. & Scancar, J.
Journal of Chromatography A (2014) 1371, 168-176
Effects of Terminal Dimethylation and Metal Coordination of Proline-2-formylpyridine Thiosemicarbazone Hybrids on Lipophilicity, Antiproliferative Activity, and hR2 RNR Inhibition
Bacher, F., Doemoetoer, O., Kaltenbrunner, M., Mojovic, M., Popovic-Bijelic, A., Graslund, A., Ozarowski, A., Filipovic, L., Radulovic, S., Enyedy, E. A. & Arion, V. B.
Inorganic Chemistry (2014) 53, 23, 12595-12609
Microwave-assisted synthesis of N-heterocycle-based organometallics
Schmidlehner, M., Kuhn, P-S., Hackl, C. M., Roller, A., Kandioller, W. & Keppler, B. K.
Journal of Organometallic Chemistry (2014) 772, 93-99
Modulation of Activity of Known Cytotoxic Ruthenium(III) Compound (KP418) with Hampered Transmembrane Transport in Electrochemotherapy In Vitro and In Vivo
Hudej, R., Miklavcic, D., Cemazar, M., Todorovic, V., Sersa, G., Bergamo, A., Sava, G., Martincic, A., Scancar, J., Keppler, B. K. & Turel, I.
Journal of Membrane Biology (2014) 247, 12, 1239-1251
Two-dimensional coordination polymers based on pyridine-containing cations of cu(II) and Ni(II) and 1,3,5-benzenetricarboxylate anion and their supramolecular structure
Tsymbal, L. V., Andriichuk, I. L., Lampeka, Y. D. & Arion, V.
Journal of Structural Chemistry (2014) 55, 8, 1466-1473
Tumor-Targeting of EGFR Inhibitors by Hypoxia-Mediated Activation
Karnthaler-Benbakka, C., Groza, D., Kryeziu, K., Pichler, V., Roller, A., Berger, W., Heffeter, P. & Kowol, C. R.
Angewandte Chemie (International Edition) (2014) 53, 47, 12930-12935
Design, synthesis and comparative cytotoxic investigation of platinum(II) complexes with some derivatives of 5-methyl-5-(4-pyridyl)hydantoin
Bakalova, A., Buyukliev, R., Varbanov, H. & Momekov, G.
Inorganica Chimica Acta (2014) 423, 46-51
Osmium(III) Analogues of KP1019: Electrochemical and Chemical Synthesis, Spectroscopic Characterization, X-ray Crystallography, Hydrolytic Stability, and Antiproliferative Activity
Kuhn, P-S., Büchel, G., Jovanovic, K. K., Filipovic, L., Radulovic, S., Rapta, P. & Arion, V. B.
Inorganic Chemistry (2014) 53, 20, 11130-11139
{Ru(CO)(x)}-core complexes with selected azoles: Synthesis, X-ray structure, spectroscopy, DFT analysis and evaluation of cytotoxic activity against human cancer cells
Tamasi, G., Carpini, A., Valensin, D., Messori, L., Pratesi, A., Scaletti, F., Jakupec, M., Keppler, B. & Cini, R.
Polyhedron (2014) 81, 227-237
Calpain-mediated integrin deregulation as novel mode of action for the anticancer gallium compound KP46. Molecular Cancer Therapeutics
Jungwirth, U., Gojo, J., Tuder, T., Walko, G., Holcmann, M., Schoefl, T., Nowikovsky, K., Wilfinger, N., Schoonhoven, S., Kowol, C. R., Lemmens, R., Heffeter, P., Keppler, B. K. & Berger, W.
Molecular Cancer Therapeutics (2014) 13, 10, 2436-2449
Diarylheptanoids, flavonoids and other constituents from two neotropical Renealmia species (Zingiberaceae)
Gilli, C., Orlowska, E., Kaiser, D., Steyrer, J., Rathgeb, A., Lorbeer, E., Brecker, L. & Schinnerl, J.
Biochemical Systematics and Ecology (2014) 56, 178-184
Tetranuclear Copper(H) Complexes with Macrocyclic and Open-Chain Disiloxane Ligands as Catalyst Precursors for Hydrocarboxylation and Oxidation of Alkanes and 1-Pheny lethanol
Zaltariov, M-F., Alexandru, M., Cazacu, M., Shova, S., Novitchi, G., Train, C., Dobrov, A., Kirillova, M. V., Alegria, E. C. B. A., Pombeiro, A. J. L. & Arion, V. B.
European Journal of Inorganic Chemistry (2014) 29, 4946-4956
Copper(II) complexes with 1,5-bis(2-hydroxybenzaldehyde) carbohydrazone
Dragancea, D., Shova, S., Enyedy, E. A., Breza, M., Rapta, P., Carrella, L. M., Rentschler, E., Dobrov, A. & Arion, V.
Polyhedron (2014) 80, 180-192
Development of potential selective and reversible pyrazoline based MAO-B inhibitors as MAO-B PET tracer precursors and reference substances for the early detection of Alzheimer's disease
Neudorfer, C., Shanab, K., Jurik, A., Schreiber, V., Neudorfer, C., Vraka, C., Schirmer, E., Holzer, W., Ecker, G., Mitterhauser, M., Wadsak, W. & Spreitzer, H.
Bioorganic & Medicinal Chemistry Letters (2014) 24, 18, 4490-4495
Complexes of N-hydroxyethyl-N-benzimidazolylmethylethylenediaminediacetic acid with copper(II) and cobalt(II): Preparation, crystal structure and urease inhibitory activity
Habala, L., Roller, A., Matuška, M., Valentová, J., Rompel, A. & Devínsky, F.
Inorganica Chimica Acta (2014) 421, 423-426
A Novel Class of Bis- and Tris-Chelate Diam(m)inebis(dicarboxylato)platinum(IV) Complexes as Potential Anticancer Prodrugs
Varbanov, H. P., Goeschl, S., Heffeter, P., Theiner, S., Roller, A., Jensen, F., Jakupec, M. A., Berger, W., Galanski, M. & Keppler, B. K.
Journal of Medicinal Chemistry (2014) 57, 15, 6751-6764
Inductively coupled plasma mass spectrometry for metallodrug development: Albumin binding and serum distribution of cytotoxic cis- and trans-isomeric platinum(II) complexes
Ossipov, K., Scaffidi-Domianello, Y. Y., Seregina, I. F., Galanski, M., Keppler, B. K., Timerbaev, A. R. & Bolshov, M. A.
Journal of Inorganic Biochemistry (2014) 137, 40-45
Total Mercury in Sediments, Macrophytes, and Fish from a Shallow Steppe Lake in Eastern Austria
Jirsa, F., Pirker, D., Krachler, R. & Keppler, B. K. Aug
Chemistry & Biodiversity (2014) 11, 8, 1263-1275
Vitamin A Is Rapidly Degraded in Retinyl Palmitate-Fortified Soybean Oil Stored under Household Conditions
Pignitter, M., Dumhart, B., Gartner, S., Jirsa, F., Steiger, G., Kraemer, K. & Somoza, V.
Journal of Agricultural and Food Chemistry (2014) 62, 30, 7559-7566
Strategy to Optimize the Biological Activity of Arene Ruthenium Metalla-Assemblies
Garci, A., Dobrov, A., Riedel, T., Orhan, E., Dyson, P. J., Arion, V. B. & Therrien, B.
Organometallics (2014) 33, 14, 3813-3822
Effect of the Piperazine Unit and Metal-Binding Site Position on the Solubility and Anti-Proliferative Activity of Ruthenium(II)- and Osmium(II)- Arene Complexes of Isomeric Indolo[3,2-c]quinoline-Piperazine Hybrids
Filak, L. K., Kalinowski, D. S., Bauer, T. J., Richardson, D. R. & Arion, V. B.
Inorganic Chemistry (2014) 53, 13, 6934-6943
Efficiently Detecting Metallodrug-Protein Adducts: Ion Trap versus Time-of-Flight Mass Analyzers
Meier, S. M., Babak, M. V., Keppler, B. K. & Hartinger, C. G.
ChemMedChem (2014) 9, 7, 1351-1355
Enhanced Anticancer Activity and Circumvention of Resistance Mechanisms by Novel Polymeric/Phospholipidic Nanocarriers of Doxorubicin
Senkiv, Y., Riabtseva, A., Heffeter, P., Boiko, N., Kowol, C. R., Jungwith, U., Shlyakhtina, Y., Garasevych, S. G., Mitina, N., Berger, W., Zaichenko, A. & Stoika, R.
Journal of Biomedical Nanotechnology (2014) 10, 7, 1369-1381
Picture change error in quasirelativistic electron/spin density, Laplacian and bond critical points
Bucinsky, L., Kuckova, L., Malcek, M., Kozisek, J., Biskupic, S., Jayatilaka, D., Büchel, G. & Arion, V. B.
Chemical Physics (2014) 438, 37-47
Can neutral analytes be concentrated by transient isotachophoresis in micellar electrokinetic chromatography and how much?
Matczuk, M., Foteeva, L. S., Jarosz, M., Galanski, M., Keppler, B. K., Hirokawa, T. & Timerbaev, A. R.
Journal of Chromatography A (2014) 1345, 212-218
Ruthenium(II)(eta(6)-arene) Complexes of Thiourea Derivatives: Synthesis, Characterization and Urease Inhibition
Hanif, M., Nawaz, M. A. H., Babak, M. V., Iqbal, J., Roller, A., Keppler, B. K. & Hartinger, C. G.
Molecules (2014) 19, 6, 8080-8092
Trace elements in sediments, blue spotted tilapia Oreochromis leucostictus (Trewavas, 1933) and its parasite Contracaecum multipapillatum from Lake Naivasha, Kenya, including a comprehensive health risk analysis
Otachi, E. O., Koerner, W., Avenant-Oldewage, A., Fellner, C. & Jirsa, F.
Environmental Science and Pollution Research (2014) 21, 12, 7339-7349
Antitumor pentamethylcyclopentadienyl rhodium complexes of maltol and allomaltol: Synthesis, solution speciation and bioactivity
Doemoetoer, O., Aicher, S., Schmidlehner, M., Novak, M. S., Roller, A., Jakupec, M. A., Kandioller, W., Hartinger, C. G., Keppler, B. K. & Enyedy, E. A.
Journal of Inorganic Biochemistry (2014) 134, 57-65
Nanoformulation Improves Activity of the (pre)Clinical Anticancer Ruthenium Complex KP1019
Heffeter, P., Riabtseva, A., Senkiv, Y., Kowol, C. R., Koerner, W., Jungwith, U., Mitina, N., Keppler, B. K., Konstantinova, T., Yanchuk, I., Stoika, R., Zaichenko, A. & Berger, W.
Journal of Biomedical Nanotechnology (2014) 10, 5, 877-884
A One-Step Microwave-Assisted Synthetic Method for an O/S-Chemoselective Route to Derivatives of the First Adenosine A3 PET Radiotracer
Shanab, K., Neudorfer, C., Holzer, W., Mitterhauser, M., Wadsak, W. & Spreitzer, H.
Molecules (2014) 19, 4, 4076-4082
Guanidine platinum(II) complexes: synthesis, in vitro antitumor activity, and DNA interactions*
Legin, A. A., Jakupec, M. A., Bokach, N. A., Tyan, M. R., Kukushkin, V. Y. & Keppler, B. K.
Journal of Inorganic Biochemistry (2014) 133, 33-39
Radioactivity in drinking water supplies in Western Australia
Walsh, M., Wallner, G. & Jennings, P.
Journal of Environmental Radioactivity (2014) 130, 56-62
Photoluminescence in Ga/Bi co-doped silica glass
Razdobreev, I., El Hamzaoui, H., Arion, V. B. & Bouazaoui, M.
Optics Express (2014) 22, 5, 5659-5674
Ruthenium-Nitrosyl Complexes with Glycine, L-Alanine, L-Valine, L-Proline, D-Proline, L-Serine, L-Threonine, and L-Tyrosine: Synthesis, X-ray Diffraction Structures, Spectroscopic and Electrochemical Properties, and Antiproliferative Activity
Rathgeb, A., Boehm, A., Novak, M. S., Gavriluta, A., Doemoetoer, O., Tornmasino, J. B., Enyedy, E. A., Shova, S., Meier, S., Jakupec, M. A., Luneau, D. & Arion, V. B.
Inorganic Chemistry (2014) 53, 5, 2718-2729
Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity
Adhireksan, Z., Davey, G. E., Campomanes, P., Groessl, M., Clavel, C. M., Yu, H., Nazarov, A. A., Yeo, C. H. F., Ang, W. H., Droege, P., Rothlisberger, U., Dyson, P. J. & Davey, C. A.
Nature Communications (2014) 5, 3462
Parasites of commercially important fish from Lake Naivasha, Rift Valley, Kenya
Otachi, E. O., Magana, A. E. M., Jirsa, F. & Fellner, C.
Parasitology Research (2014) 113, 3, 1057-1067
Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
Trondl, R., Flocke, L. S., Kowol, C. R., Heffeter, P., Jungwirth, U., Mair, G. E., Steinborn, R., Enyedy, E. A., Jakupec, M. A., Berger, W. & Keppler, B. K.
Molecular Pharmacology (2014) 85, 3, 451-459
Comparison of the Sequence-Dependent Fluorescence of the Cyanine Dyes Cy3, Cy5, DyLight DY547 and DyLight DY647 on Single-Stranded DNA
Kretschy, N. & Somoza, M. M.
PLoS ONE (2014) 9, 1, e85605
Solution equilibrium studies of anticancer ruthenium(II)-eta(6)-p-cymene complexes of pyridinecarboxylic acids
Sija, E., Hartinger, C. G., Keppler, B. K., Kiss, T. & Enyedy, E. A.
Polyhedron (2014) 67, 51-58
Ruthenium(II)-arene complexes with substituted picolinato ligands: Synthesis, structure, spectroscopic properties and antiproliferative activity
Ivanovic, I., Jovanovic, K. K., Gligorijevic, N., Radulovic, S., Arion, V. B., Sheweshein, K. S. A. M., Tesic, Z. L. & Grguric-Sipka, S.
Journal of Organometallic Chemistry (2014) 749, 343-349
Synthesis, X-ray structure and strong in vitro cytotoxicity of novel organoruthenium complexes
Mojic, M., Savic, A., Arion, V. B., Bulatovic, M., Poljarevic, J. M., Miljkovic, D., Sabo, T. J., Mijatovic, S., Maksimovic-Ivanic, D. & Grguric-Sipka, S.
Journal of Organometallic Chemistry (2014) 749, 142-149
µ-Chlorido-Bridged Dimanganese(II) Complexes of the Schiff Base Derived from [2+2] Condensation of 2,6-Diformyl-4-methylphenol and 1,3-Bis(3-aminopropyl)tetramethyldisiloxane: Structure, Magnetism, Electrochemical Behaviour, and Catalytic Oxidation of Secondary Alcohols
Alexandru, M., Cazacu, M., Arvinte, A., Shova, S., Turta, C., Simionescu, B. C., Dobrov, A., Alegria, E. C. B. A., Martins, L. M. D. R. S., Pombeiro, A. J. L. & Arion, V. B.
European Journal of Inorganic Chemistry (2014) 1, 120-131
Platinum(IV) Complexes Featuring One or Two Axial Ferrocene Bearing Ligands - Synthesis, Characterization, and Cytotoxicity
Banfic, J., Legin, A. A., Jakupec, M. A., Galanski, M. & Keppler, B. K.
European Journal of Inorganic Chemistry (2014) 3, 484-492
Aqueous chemistry and antiproliferative activity of a pyrone-based phosphoramidate Ru(arene) anticancer agent
Meier, S. M., Novak, M. S., Kandioller, W., Jakupec, M. A., Roller, A., Keppler, B. K. & Hartinger, C. G.
Dalton Transactions (Print Edition) (2014) 43, 26, 9851-9855
Base-cleavable microarrays for the characterization of DNA and RNA oligonucleotides synthesized in situ by photolithography
Lietard, J., Kretschy, N., Sack, M., Wahba, A. S., Somoza, M. M. & Damha, M. J.
Chemical Communications (2014) 50, 85, 12903-12906
First limnological records of highly threatened tropical high-mountain crater lakes in Ethiopia
Degefu, F., Herzig, A., Jirsa, F. & Schagerl, M.
Tropical Conservation Science (2014) 7, 3, 365-381
NanoSIMS combined with fluorescence microscopy as a tool for subcellular imaging of isotopically labeled platinum-based anticancer drugs
Legin, A. A., Schintlmeister, A., Jakupec, M. A., Galanski, M., Lichtscheidl-Schultz, I., Wagner, M. & Keppler, B. K.
Chemical Science (2014) 5, 8, 3135-3143
NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application
Trondl, R., Heffeter, P., Kowol, C. R., Jakupec, M. A., Berger, W. & Keppler, B. K.
Chemical Science (2014) 5, 8, 2925-2932
Poly(lactic acid) nanoparticles of the lead anticancer ruthenium compound KP1019 and its surfactant-mediated activation
Fischer, B., Heffeter, P., Kryeziu, K., Gille, L., Meier, S. M., Berger, W., Kowol, C. R. & Keppler, B. K.
Dalton Transactions (Print Edition) (2014) 43, 3, 1096-1104
Quantitative bioimaging by LA-ICP-MS: a methodological study on the distribution of Pt and Ru in viscera originating from cisplatin- and KP1339-treated mice
Egger, A. E., Theiner, S., Kornauth, C., Heffeter, P., Berger, W., Keppler, B. K. & Hartinger, C.
Metallomics (2014) 6, 9, 1616-1625