Radiosynthesis of [C-11]SNAP-7941-the first PET-tracer for the melanin concentrating hormone receptor 1 (MCHR1)

Author(s)
Cecile Philippe, Eva Schirmer, Markus Mitterhauser, Karem Shanab, Rupert Lanzenberger, Georgios Karanikas, Helmut Spreitzer, Helmut Viernstein, Wolfgang Wadsak
Abstract

The melanin concentrating hormone (MCH) system is a new target to treat human disorders. Our aim was the preparation of the first PET-tracer for the MCHR1. [C-11]SNAP-7941 is a carbon-11 labeled analog of the published MCHR1 antagonist SNAP-7941. The optimum reaction conditions were 2 min reaction time,

Organisation(s)
Department of Inorganic Chemistry
External organisation(s)
Medizinische Universität Wien
Journal
Applied Radiation and Isotopes
Volume
70
Pages
2287-2294
No. of pages
8
ISSN
0969-8043
DOI
https://doi.org/10.1016/j.apradiso.2012.07.010
Publication date
2012
Peer reviewed
Yes
Austrian Fields of Science 2012
302054 Nuclear medicine, 104003 Inorganic chemistry
Portal url
https://ucrisportal.univie.ac.at/en/publications/06d6d2bd-a0cf-4e77-b5ef-5e27703a876e