X-ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism

Author(s)
Aleksandar Bijelic, Sarah Theiner, Bernhard K. Keppler, Annette Rompel
Organisation(s)
Department of Biophysical Chemistry, Department of Inorganic Chemistry
Journal
Journal of Medicinal Chemistry
Volume
59
Pages
5894-5903
No. of pages
10
ISSN
0022-2623
DOI
https://doi.org/10.1021/acs.jmedchem.6b00600
Publication date
06-2016
Peer reviewed
Yes
Austrian Fields of Science 2012
301305 Medical chemistry, 301206 Pharmacology
Keywords
ASJC Scopus subject areas
Drug Discovery, Molecular Medicine
Portal url
https://ucrisportal.univie.ac.at/en/publications/2d69a6d5-f684-4d2c-afce-611c1109a6f2