Maleimide-functionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery

Author(s)
Verena Pichler, Josef Mayr, Petra Heffeter, Orsolya Domotor, Eva Anna Enyedy, Gerrit Hermann, Diana Groza, Gunda Köllensperger, Mathea Sophia Galanski, Walter Berger, Bernhard Keppler, Christian Kowol
Abstract

Maleimide-functionalised Pt(IV) complexes with highly selective binding properties to thiol groups were synthesised as precursors for binding of thiol-containing tumour-targeting molecules like human serum albumin.

Organisation(s)
Department of Inorganic Chemistry
External organisation(s)
Medizinische Universität Wien, University of Szeged, University of Natural Resources and Life Sciences
Journal
Chemical Communications
Volume
49
Pages
2249-2251
No. of pages
3
ISSN
1359-7345
DOI
https://doi.org/10.1039/c3cc39258a
Publication date
2013
Peer reviewed
Yes
Austrian Fields of Science 2012
104003 Inorganic chemistry, 301207 Pharmaceutical chemistry
Portal url
https://ucrisportal.univie.ac.at/en/publications/415b56f9-ba43-46ce-87f2-f2d30ab379c7