From pyrone to thiopyrone ligands-rendering maltol-derived ruthenium(II)-arene complexes that are anticancer active in vitro
- Author(s)
- Wolfgang Kandioller, Christian Hartinger, Alexey Nazarov, Maxim L. Kuznetsov, Roland John, Caroline Bartel, Michael Jakupec, Vladimir Arion, Bernhard Keppler
- Abstract
Ru(II)-arene complexes with pyrone-derived Iigands are rendered active against cancer cells by replacement of the coordinated 0,0 donor with an S,0 donor. The different stabilities of these systems may explain the observed influence of the donor atoms on the anticancer activity in vitro.
- Organisation(s)
- Department of Inorganic Chemistry
- External organisation(s)
- Universidade Técnica de Lisboa
- Journal
- Organometallics
- Volume
- 28
- Pages
- 4249-4251
- No. of pages
- 3
- ISSN
- 0276-7333
- DOI
- https://doi.org/10.1021/om900483t
- Publication date
- 2009
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 104003 Inorganic chemistry, 301305 Medical chemistry
- Sustainable Development Goals
- SDG 3 - Good Health and Well-being
- Portal url
- https://ucrisportal.univie.ac.at/en/publications/48cc07b8-ef46-4ea4-bace-b047310a80ac