Complex-Formation Ability of Salicylaldehyde Thiosemicarbazone towards ZnII, CuII, FeII, FeIII and GaIII Ions
- Author(s)
- Eva Anna Enyedy, Eva Zsigo, Nóra Veronika Nagy, Christian Kowol, Alexander Roller, Bernhard Keppler, Tamas Kiss
- Abstract
The stoichiometry and stability of copper(II), zinc(II), iron(II)/(III) and gallium(III) complexes of salicylaldehyde thiosemicarbazone (STSC, H2L) have been determined by pH potentiometry, UV/Vis spectrophotometry, and 1H NMR and EPR spectroscopy in aqueous solution (with 30?% DMSO), together with the characterization of the proton dissociation processes. Mono- and bis-ligand complexes in different protonation states were identified for FeII, FeIII and GaIII, whereas CuII and ZnII ions only form complexes with a 1:1 metal/ligand ratio. The coordination mode in the complex [Zn2(HL)(L)(OAc)EtOH] was confirmed by X-ray diffraction. The metal-binding ability of STSC at physiological pH is in the following order: GaIII <ZnII <FeII <FeIII <CuII. GaIIISTSC complexes show unambiguously higher stability, whereas FeIISTSC species show significantly lower stability relative to the corresponding a(N)-pyridyl thiosemicarbazones like 2-formylpyridine thiosemicarbazone or Triapine. Furthermore, the fluorescence properties of the ligand were investigated in aqueous solution, and their changes caused by complexation with GaIII and ZnII were studied.
- Organisation(s)
- Department of Inorganic Chemistry
- External organisation(s)
- University of Szeged, Hungarian Academy of Sciences
- Journal
- European Journal of Inorganic Chemistry
- Volume
- 25
- Pages
- 4036-4047
- No. of pages
- 12
- ISSN
- 1434-1948
- DOI
- https://doi.org/10.1002/ejic.201200360
- Publication date
- 2012
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 104003 Inorganic chemistry
- Portal url
- https://ucrisportal.univie.ac.at/en/publications/5a9d23d1-6176-4d86-828d-e48a989f7334