Mass spectrometry-based analysis of eccrine sweat supports predictive, preventive and personalised medicine in a cohort of breast cancer patients in Austria
- Author(s)
- Michael Bolliger, Daniel Wasinger, Julia Brunmair, Gerhard Hagn, Michael Wolf, Karin Preindl, Birgit Reiter, Andrea Bileck, Christopher Gerner, Florian Fitzal, Samuel M. Meier-Menches
- Abstract
Metabolomics measurements of eccrine sweat may provide novel and relevant biomedical information to support predictive, preventive and personalised medicine (3PM). However, only limited data is available regarding metabolic alterations accompanying chemotherapy of breast cancer patients related to residual cancer burden (RCB) or therapy response. Here, we have applied Metabo-Tip, a non-invasive metabolomics assay based on the analysis of eccrine sweat from the fingertips, to investigate the feasibility of such an approach, especially with respect to drug monitoring, assessing lifestyle parameters and stratification of breast cancer patients.
- Organisation(s)
- Department of Analytical Chemistry, Joint Metabolome Facility, Department of Inorganic Chemistry
- External organisation(s)
- Medizinische Universität Wien, Vienna Doctoral School in Chemistry (DoSChem), Karolinska Institute, University of Vienna, Hanusch Krankenhaus Wien
- Journal
- The EPMA journal
- ISSN
- 1878-5085
- DOI
- https://doi.org/10.1007/s13167-025-00396-6
- Publication date
- 2025
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 104002 Analytical chemistry, 301904 Cancer research
- Sustainable Development Goals
- SDG 3 - Good Health and Well-being
- Portal url
- https://ucrisportal.univie.ac.at/en/publications/7f0a64f9-d8d8-463e-9808-f1d602ac5adb