Ruthenium- and osmium-arene-based paullones bearing a TEMPO free-radical unit as potential anticancer drugs
- Author(s)
- Vladimir Arion, Anatolie Dobrov, Simone Göschl, Michael Jakupec, Bernhard Keppler, Peter Rapta
- Abstract
A modified paullone ligand bearing a TEMPO free-radical unit (HL) and its ruthenium(II) and osmium(II)-arene complexes [M(p-cymene)(HL) Cl]Cl center dot nH(2)O (M = Ru, Os) exhibit high antiproliferative activity in human cancer cell lines.
- Organisation(s)
- Department of Inorganic Chemistry
- External organisation(s)
- Slovak University of Technology in Bratislava
- Journal
- Chemical Communications
- Volume
- 48
- Pages
- 8559-8561
- No. of pages
- 3
- ISSN
- 1359-7345
- DOI
- https://doi.org/10.1039/c2cc33786j
- Publication date
- 2012
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 104003 Inorganic chemistry
- Sustainable Development Goals
- SDG 3 - Good Health and Well-being
- Portal url
- https://ucrisportal.univie.ac.at/en/publications/62991fdf-8b37-4fa7-9728-f71739275e6f