Synthesis and characterization of [(1R,2R)-trans-diaminocyclohexane]- platinum(II) coordinated to sulfur and selenium amino acids

Author(s)
Claudia Rothenburger, Mathea Sophia Galanski, Vladimir Arion, Helmar Görls, Wolfgang Weigand, Bernhard Keppler
Abstract

Dichloro[(1R,2R)-trans-diaminocyclohexane]platinum(II) was activated with Ag2CO3 and then treated with (S)-methionine, S-methyl-(S)-cysteine, (S)-selenomethionine and Se-methyl-seleno-(S)-cysteine. The N,S- and N,Se-chelated platinum(II) species were isolated as hexafluorophosphate salts and characterized by multinuclear NMR spectroscopy, ESI-MS, IR, elemental analyses and, in the case of the (S)-methionine and (S)-selenomethionine complexes, by X-ray crystallography. Œ Wiley-VCH Verlag GmbH & Co. KGaA, 2006.

Organisation(s)
Department of Inorganic Chemistry, Department of Organic Chemistry
External organisation(s)
Friedrich-Schiller-Universität Jena
Journal
European Journal of Inorganic Chemistry
Pages
3746-3752
No. of pages
7
ISSN
1434-1948
Publication date
2006
Peer reviewed
Yes
Austrian Fields of Science 2012
1040 Chemistry
Portal url
https://ucrisportal.univie.ac.at/en/publications/78a8fce3-2248-44e3-a264-19405ef55301