The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition
- Author(s)
- Sonja Hager, Katharina Korbula, Bjoern Bielec, Michael Grusch, Christine Pirker, Markus Schosserer, Lisa Liendl, Magdalena Lang, Johannes Grillari, Karin Nowikoysky, Veronika F. S. Pape, Thomas Mohr, Gergely Szakacs, Bernhard K. Keppler, Walter Berger, Christian R. Kowol, Petra Heffeter
- Organisation(s)
- Department of Inorganic Chemistry
- External organisation(s)
- Medizinische Universität Wien, Research Cluster Translational Cancer Therapy Research, University of Natural Resources and Life Sciences, Evercyte GmbH, Semmelweis University , Hungarian Academy of Sciences, Sci Consult DI Thomas Mohr KG
- Journal
- Cell Death & Disease
- Volume
- 9
- No. of pages
- 17
- ISSN
- 2041-4889
- DOI
- https://doi.org/10.1038/s41419-018-1102-z
- Publication date
- 10-2018
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 301114 Cell biology
- Keywords
- ASJC Scopus subject areas
- Cellular and Molecular Neuroscience, Cancer Research, Cell Biology, Immunology
- Sustainable Development Goals
- SDG 3 - Good Health and Well-being
- Portal url
- https://ucrisportal.univie.ac.at/en/publications/880e0026-5e80-4ea3-9c3e-0f72c0373fa1