New aspects on the preparation of [11C]acetate - A simple and fast approach via distillation
- Author(s)
- Markus Mitterhauser, Wolfgang Wadsak, Harald Eidherr, Helmut Viernstein, Kurt Kletter
- Abstract
[11C]Acetate, initially developed for nuclear cardiology has gained increased interest also for oncological problems. A conjoint problem of all preparation methods is the high sensitivity of the Grignard-precursor to moisture, demanding long cleaning and drying procedures of apparatus and reaction vials. Our rationale was to simplify and accelerate the preparation of [11C]acetate by the development of an inert, sterile and disposable system. The present publication deals with the remote-controlled preparation of [11C]acetate via distillation into a buffer ready to use. Π2004 Elsevier Ltd. All rights reserved.
- Organisation(s)
- Department of Inorganic Chemistry
- Journal
- Applied Radiation and Isotopes
- Volume
- 61
- Pages
- 1147-1150
- No. of pages
- 4
- ISSN
- 0969-8043
- Publication date
- 2004
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 3012 Pharmacy, Pharmacology, Toxicology
- Portal url
- https://ucrisportal.univie.ac.at/en/publications/99de612a-72ff-47c7-95b0-2abc1943c63c