Intrinsic fluorescence of the clinically approved multikinase inhibitor nintedanib reveals lysosomal sequestration as resistance mechanism in FGFR-driven lung cancer

Author(s)
Bernhard Englinger, Sebastian Kallus, Julia Senkiv, Daniela Heilos, Lisa Gabler, Sushilla Van Schoonhoven, Alessio Terenzi, Patrick Moser, Christine Pirker, Gerald Timelthaler, Walter Jaeger, Christian R. Kowol, Petra Heffeter, Michael Grusch, Walter Berger
Organisation(s)
Department of Inorganic Chemistry
External organisation(s)
Medizinische Universität Wien
Journal
Journal of Experimental and Clinical Cancer Research
Volume
36
No. of pages
13
ISSN
1756-9966
DOI
https://doi.org/10.1186/s13046-017-0592-3
Publication date
09-2017
Peer reviewed
Yes
Austrian Fields of Science 2012
301904 Cancer research
Keywords
ASJC Scopus subject areas
Oncology, Cancer Research
Sustainable Development Goals
SDG 3 - Good Health and Well-being
Portal url
https://ucrisportal.univie.ac.at/en/publications/ec76b0aa-ae0e-4a96-a47d-85a0b3960c5f