Basics and principles of radiopharmaceuticals for PET/CT
- Author(s)
- Wolfgang Wadsak, Markus Mitterhauser
- Abstract
The presented review provides general background on PET radiopharmaceuticals for oncological applications. Special emphasis is put on radiopharmacological, radiochemical and regulatory aspects. This review is not meant to give details on all different PET tracers in depth but to provide insights into the general principles coming along with their preparation and use. The PET tracer plays a pivotal role because it provides the basis both for image quality and clinical interpretation. It is composed of the radionuclide (signaller) and the molecular vehicle which determines the (bio-)chemical properties (e.g. binding characteristics, metabolism, elimination rate).
- Organisation(s)
- External organisation(s)
- Medizinische Universität Wien
- Journal
- European Journal of Radiology
- Volume
- 73
- Pages
- 461-469
- No. of pages
- 9
- ISSN
- 0720-048X
- DOI
- https://doi.org/10.1016/j.ejrad.2009.12.022
- Publication date
- 2010
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 302071 Radiology, 3012 Pharmacy, Pharmacology, Toxicology
- Portal url
- https://ucrisportal.univie.ac.at/en/publications/f1e286f4-3237-4478-b2d0-fa7ffcd97a7e