Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules
- Author(s)
- Alexey A. Nazarov, Anton Legin, Michael Größl, Vladimir Arion, Michael Jakupec, Yury O. Tsybin, Paul J. Dyson, Bernhard Keppler, Christian Hartinger
- Abstract
Ru(II)(arene) anticancer compounds with maleimide functionality were prepared to allow selective interaction with thiol-containing biomolecules and thereby enforcing the selective delivery of the compounds to the tumour.
- Organisation(s)
- Department of Inorganic Chemistry
- External organisation(s)
- École polytechnique fédérale de Lausanne
- Journal
- Chemical Communications
- Volume
- 48
- Pages
- 1475-1477
- No. of pages
- 3
- ISSN
- 1359-7345
- DOI
- https://doi.org/10.1039/c1cc14713g
- Publication date
- 2012
- Peer reviewed
- Yes
- Austrian Fields of Science 2012
- 301206 Pharmacology, 104003 Inorganic chemistry
- Portal url
- https://ucrisportal.univie.ac.at/en/publications/778f21b5-c1a4-435a-ab04-0189ed533a80