o. Univ.-Prof. Dr. Dr. Bernhard Keppler

Email: bernhard.keppler@univie.ac.at
Phone: +43-1-4277-52602

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Publications


Loss of CUL4A expression is underlying cisplatin hypersensitivity in colorectal carcinoma cells with acquired trabectedin resistance. / Englinger, B.; Mair, M.; Miklos, W. et al.
In: British Journal of Cancer, Vol. 116, No. 4, 14.02.2017, p. 489-500.

Publications: Contribution to journalArticlePeer Reviewed


Metal NHC Complexes with Naphthalimide Ligands as DNA-Interacting Antiproliferative Agents. / Streciwilk, Wojciech; Terenzi, Alessio; Misgeld, Rainer et al.
In: ChemMedChem: chemistry enabling drug discovery, Vol. 12, No. 3, 03.02.2017, p. 214-225.

Publications: Contribution to journalArticlePeer Reviewed


Response Profiling Using Shotgun Proteomics Enables Global Metallodrug Mechanisms of Action To Be Established. / Kreutz, Dominique; Bileck, Andrea; Plessl, Kerstin et al.
In: Chemistry: A European Journal, Vol. 23, No. 8, 03.02.2017, p. 1881-1890.

Publications: Contribution to journalArticlePeer Reviewed


Electronic State of Sodium trans-[Tetrachloridobis(1H-indazole)ruthenate(III)] (NKP-1339) in Tumor, Liver and Kidney Tissue of a SW480-bearing Mouse. / Blazevic, Amir; Hummer, Alfred A.; Heffeter, Petra et al.
In: Scientific Reports, Vol. 7, 40966, 23.01.2017.

Publications: Contribution to journalArticlePeer Reviewed


Synthetic iron complexes as models for natural iron-humic compounds: Synthesis, characterization and algal growth experiments. / Orlowska, Ewelina; Roller, Alexander; Pignitter, Marc et al.
In: Science of the Total Environment, Vol. 577, 15.01.2017, p. 94-104.

Publications: Contribution to journalArticlePeer Reviewed


HPLC-MS Untersuchungen zur elektrochemischen Freisetzung von Pt(II) Zytostatika aus Pt(IV)-Prodrugs. / Frensemeier, Lisa ; Köllensperger, Gunda; Kowol, Christian et al.
2017. Paper presented at 27. Doktorandenseminar des AK Separation Science, Hohenroda, Germany.

Publications: Contribution to conferencePaper


Introducing the 4-Phenyl-1,2,3-Triazole Moiety as a Versatile Scaffold for the Development of Cytotoxic Ruthenium(II) and Osmium(II) Arene Cyclometalates. / Riedl, Christoph A.; Flocke, Lea S.; Hejl, Michaela et al.
In: Inorganic Chemistry, Vol. 56, No. 1, 03.01.2017, p. 528-541.

Publications: Contribution to journalArticlePeer Reviewed


Association between improved liver function and selenium depends on C718T polymorphism in 3 '-untranslated region of glutathione peroxidase 4 and in humans. / Rohr-Udilova, Nataliya; Theiner, S.; Beinhardt, S. et al.
In: Journal of Hepatology, Vol. 66, No. S 1, 2017, p. S496-S497.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Influence of the Number of Axial Bexarotene Ligands on the Cytotoxicity of Pt(IV) Analogs of Oxaliplatin. / Nosova, Yulia N.; Zenin, Ilia V.; Maximova, Varvara P. et al.
In: Bioinorganic Chemistry and Applications, Vol. 2017, 4736321, 2017.

Publications: Contribution to journalArticlePeer Reviewed


Self-assembled Pt2L2 boxes strongly bind G-quadruplex DNA and influence gene expression in cancer cells. / Domarco, O.; Loetsch, D.; Schreiber, J. et al.
In: Dalton Transactions, Vol. 46, No. 2, 2017, p. 329-332.

Publications: Contribution to journalArticlePeer Reviewed


Loss of phosphodiesterase 4D mediates acquired triapine resistance via Epac-Rap1-Integrin signaling. / Miklos, Walter; Heffeter, Petra; Pirker, Christine et al.
In: Onco Target, Vol. 7, No. 51, 20.12.2016, p. 84556-84574.

Publications: Contribution to journalArticlePeer Reviewed


DNA-Binding and Anticancer Activity of Pyrene-Imidazolium Derivatives. / Bonsignore, Riccardo; Notaro, Antonietta; Salvo, Anna Maria Pia et al.
In: Chemistry SELECT, Vol. 1, No. 21, 16.12.2016, p. 6755–6761 .

Publications: Contribution to journalArticlePeer Reviewed


Anticancer metal drugs and immunogenic cell death. / Terenzi, Alessio; Pirker, Christine; Keppler, Bernhard K. et al.
In: Journal of Inorganic Biochemistry, Vol. 165, 12.2016, p. 71-79.

Publications: Contribution to journalArticlePeer Reviewed


Thiomaltol-Based Organometallic Complexes with 1-Methylimidazole as Leaving Group: Synthesis, Stability, and Biological Behavior. / Hackl, Carmen M.; Legina, Maria S.; Pichler, Verena et al.
In: Chemistry: A European Journal, Vol. 22, No. 48, 21.11.2016, p. 17269-17281.

Publications: Contribution to journalArticlePeer Reviewed


Targeting a Targeted Drug: An Approach Toward Hypoxia-Activatable Tyrosine Kinase Inhibitor Prodrugs. / Karnthaler-Benbakka, Claudia; Groza, Diana; Koblmueller, Bettina et al.
In: ChemMedChem: chemistry enabling drug discovery, Vol. 11, No. 21, 07.11.2016, p. 2410-2421.

Publications: Contribution to journalArticlePeer Reviewed


Chapter 13: Biomedical and Pharmaceutical Applications. / Sonet, Jordan ; Bulteau, Anne-Laure ; Chavatte, Laurent et al.
Metallomics: Analytical Techniques and Speciation Methods. ed. / Bernhard Michalke. Wiley Online Library, 2016. p. 359-462.

Publications: Contribution to bookChapterPeer Reviewed


Ruthenium-based drug distribution in colon cancer 2D and 3D cell cultures revealed by correlative NanoSIMS and TEM imaging. / Legin, Anton; Schintlmeister, Arno; Reipert, Siegfried et al.
Book of Abstracts: SIMS Europe 2016, 18 - 20.09.16, Münster, Deutschland. 2016.

Publications: Contribution to bookContribution to proceedings


HEAVY METALS IN THE MALLARD ANAS PLATYRHYNCHOS FROM EASTERN AUSTRIA. / Plessl, Christof; Jandrisits, P.; Krachler, Regina et al.
Abstract Book of the 18th International Conference on Heavy Metals in the Environment. 2016. p. 599 - 600.

Publications: Contribution to bookContribution to proceedingsPeer Reviewed


Towards targeting anticancer drugs: ruthenium(II)-arene complexes with biologically active naphthoquinone-derived ligand systems. / Kubanik, Mario; Kandioller, Wolfgang; Kim, Kunwoo et al.
In: Dalton Transactions, Vol. 45, No. 33, 07.09.2016, p. 13091-13103.

Publications: Contribution to journalArticlePeer Reviewed


Investigation of Triapine metabolism by application of electrochemistry and liquid chromatography coupled to mass spectrometry (EC/LC/ESI-MS). / Pelivan, Karla; Frensemeier, Lisa ; Karst, Uwe et al.
Book of Abstracts. 2016.

Publications: Contribution to bookContribution to proceedingsPeer Reviewed