o. Univ.-Prof. Dr. Dr. Bernhard Keppler

Email: bernhard.keppler@univie.ac.at
Phone: +43-1-4277-52602

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Publications


Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)] trithiocyanate (KP772; FFC24). / Heffeter, Petra; Jakupec, Michael; Körner, Wilfried et al.
In: Biochemical Pharmacology, Vol. 71, No. 4, 2006, p. 426-440.

Publications: Contribution to journalArticlePeer Reviewed


Anticancer activity of the lanthanum drug KP772 (FFC24): impact of the p53 status. / Heffeter, Petra; Jakupec, Michael; Dornetshuber, Rita et al.
Proceedings of the 9th International Symposium on Metal Ions in Biology and Medicine: held in Lisboa, Portugal, Europe on May 21 - 24, 2006. Vol. 9 Paris: John Libbey Eurotext, 2006. p. 260-266 (Metal ions in biology and medicine).

Publications: Contribution to bookContribution to proceedings


Crystal structure of trans-dichloro(dimethylsulfoxide)(diphenylsulfimide)- platinum(II) toluene hemisolvate, PtCl2(C2H 6SO)(C12H10SNH) ž 1/2C7H 8. / Scaffidi-Domianello, Yulia; Haukka, M; Kelly, Paul F et al.
In: Zeitschrift für Kristallographie - New Crystal Structures, Vol. 221, No. 2, 2006, p. 226-228.

Publications: Contribution to journalArticlePeer Reviewed


Determination of cisplatin and its hydrolytic metabolite in human serum by capillary electrophoresis techniques. / Huang, Zhuo; Timerbaev, Andrei; Keppler, Bernhard et al.
In: Journal of Chromatography A, Vol. 1106, No. 1-2, 2006, p. 75-79.

Publications: Contribution to journalArticlePeer Reviewed


Divergent effects of complexation with gallium(III) or iron(III) on the antitumor potency of 2-acetylpyridine-4N-dimethylthiosemicarbazone. / Eichinger, Rene; Kowol, Christian; Arion, Vladimir et al.
Proceedings of the 9th International Symposium on Metal Ions in Biology and Medicine: held in Lisboa, Portugal, Europe on May 21 - 24, 2006. ed. / Maria Carmen Alpiom. Vol. 9 Paris: John Libbey Eurotext, 2006. p. 30-34 (Metal ions in biology and medicine).

Publications: Contribution to bookContribution to proceedings


DNA interactions of pH-sensitive, antitumor bis(aminoalcohol) dichloroplatinum(II) complexes. / Zorbas-Seifried, Stefanie; Hartinger, Christian; Meelich, Kristof et al.
In: Biochemistry, Vol. 45, No. 49, 2006, p. 14817-14825.

Publications: Contribution to journalArticlePeer Reviewed


Electrospray ionization mass spectrometric study on the coordination behavior of dacarbazine towards transition metal ions. / Hartinger, Christian; Mendoza Parra Ferri, Maria Grazia; Nazarov, Alexey et al.
In: Polyhedron, Vol. 25, No. 9, 2006, p. 1971-1978.

Publications: Contribution to journalArticlePeer Reviewed


From bench to bedside - preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A). / Hartinger, Christian; Zorbas-Seifried, Stefanie; Jakupec, Michael et al.
In: Journal of Inorganic Biochemistry, Vol. 100, No. 5-6, 2006, p. 894-904.

Publications: Contribution to journalArticlePeer Reviewed


Impact of biological reductants on GMP binding of trans-[RuIIICl4(Hind)2]- and preparation of a model nucleobase adduct. / Egger, Alexander; Hartinger, Christian; Arion, Vladimir et al.
Proceedings of the 9th International Symposium on Metal Ions in Biology and Medicine: held in Lisboa, Portugal, Europe on May 21 - 24, 2006: Metal ions in biology and medicine 9. ed. / Maria Carmen Alpoim. Paris: John Libbey Eurotext, 2006. p. 24-29.

Publications: Contribution to bookContribution to proceedings


Interactions of antitumor metallodrugs with serum proteins: Advances in characterization using modern analytical methodology. / Timerbaev, Andrei; Hartinger, Christian (Corresponding author); Aleksenko, Svetlana S. et al.
In: Chemical Reviews, Vol. 106, No. 6, 2006, p. 2224-2248.

Publications: Contribution to journalReviewPeer Reviewed


Metallodrug research and analysis using capillary electrophoresis. / Timerbaev, Andrei; Hartinger, Christian; Keppler, Bernhard.
In: Trends in Analytical Chemistry, Vol. 25, No. 9, 2006, p. 868-875.

Publications: Contribution to journalArticlePeer Reviewed


NCA nucleophilic radiofluorination on substituted benzaldehydes for the preparation of [18F]fluorinated aromatic amino acids. / Wadsak, Wolfgang; Wirl-Sagadin, Barbara; Mitterhauser, Markus et al.
In: Applied Radiation and Isotopes, Vol. 64, No. 3, 2006, p. 355-359.

Publications: Contribution to journalArticlePeer Reviewed


Platinum group metallodrug-protein binding studies by capillary electrophoresis-inductively coupled plasma-mass spectrometry: a further insight into the reactivity of a novel antitumor ruthenium(III) complex toward human serum proteins. / Polec-Pawlak, Katarzyna; Abramski, Jan K.; Semenova, Olga et al.
In: Electrophoresis, Vol. 27, No. 5-6, 2006, p. 1128-1135.

Publications: Contribution to journalArticlePeer Reviewed


Preclinical and early clinical development of the antitumor gallium complex KP46 (FFC11). / Collery, Philippe; Jakupec, Michael; Kynast, Bernd et al.
Proceedings of the 9th International Symposium on Metal Ions in Biology and Medicine: held in Lisboa, Portugal, Europe on May 21 - 24, 2006. ed. / Maria Carmen Alpiom. Vol. 9 Paris: John Libbey Eurotext, 2006. p. 521-524 (Metal ions in biology and medicine).

Publications: Contribution to bookContribution to proceedings


Preclinical characterization of anticancer gallium(III) complexes: solubility, stability, lipophilicity and binding to serum proteins. / Timerbaev, Andrei (Corresponding author); Rudnev, Alexander V.; Foteeva, Lidia S. et al.
In: Journal of Inorganic Biochemistry, Vol. 100, No. 11, 2006, p. 1819-1826.

Publications: Contribution to journalArticlePeer Reviewed


Redox behavior of tumor-inhibiting ruthenium(III) complexes and effects of physiological reductants on their binding to GMP. / Schluga, Petra; Hartinger, Christian (Corresponding author); Egger, Alexander et al.
In: Dalton Transactions, Vol. 14, 2006, p. 1796-1802.

Publications: Contribution to journalArticlePeer Reviewed


Ruthenium(III)-arene complex with heterocyclic ligands as prospective antitumor agent. / John, Roland; Arion, Vladimir; Jakupec, Michael et al.
Proceedings of the 9th International Symposium on Metal Ions in Biology and Medicine: held in Lisboa, Portugal, Europe on May 21 - 24, 2006. ed. / Maria Carmen Alpiom. Vol. 9 Paris: John Libbey Eurotext, 2006. p. 40-46 (Metal ions in biology and medicine).

Publications: Contribution to bookContribution to proceedings


Synthesis and characterization of [(1R,2R)-trans-diaminocyclohexane]- platinum(II) coordinated to sulfur and selenium amino acids. / Rothenburger, Claudia; Galanski, Mathea Sophia (Corresponding author); Arion, Vladimir et al.
In: European Journal of Inorganic Chemistry, No. 18, 2006, p. 3746-3752.

Publications: Contribution to journalArticlePeer Reviewed


Synthesis and In Vitro Antitumor Activity of 2,3-Diaminoglucose-Based Platinum(II) Coordination Compounds. / Berger, Isabella; Nazarov, Alexey; Hartinger, Christian et al.
Proceedings of the 9th International Symposium on Metal Ions in Biology and Medicine: held in Lisboa, Portugal, Europe on May 21 - 24, 2006. ed. / Carmen Alpoim. Vol. 9 Paris [u.a.]: John Libbey Eurotext, 2006. p. 9-12 (Metal ions in biology and medicine).

Publications: Contribution to bookContribution to proceedings