o. Univ.-Prof. Dr. Dr. Bernhard Keppler

Email: bernhard.keppler@univie.ac.at
Phone: +43-1-4277-52602

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Publications


Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexes. / Hanif, Muhammad; Meier, Samuel Matthias; Nazarov, Alexey A. et al.
In: Frontiers in Chemistry, Vol. 1, 27, 31.10.2013.

Publications: Contribution to journalArticlePeer Reviewed


Solution equilibria of anticancer ruthenium(II)-(eta(6)-p-cymene)-hydroxy(thio)pyr(id) one complexes: Impact of sulfur vs. oxygen donor systems on the speciation and bioactivity. / Enyedy, Eva A.; Sija, Eva; Jakusch, Tamas (Corresponding author) et al.
In: Journal of Inorganic Biochemistry, Vol. 127, 10.2013, p. 161-168.

Publications: Contribution to journalArticlePeer Reviewed


The ruthenium compound KP1339 potentiates the anticancer activity of sorafenib in vitro and in vivo. / Heffeter, Petra; Atil, Bihter; Kryeziu, Kushtrim et al.
In: European Journal of Cancer, Vol. 49, No. 15, 10.2013, p. 3366-3375.

Publications: Contribution to journalArticlePeer Reviewed


New ruthenium(II)-arene complexes bearing hydrazides and the corresponding (thio)semicarbazones of 3-and 4-acetylpyridine: Synthesis, characterization, crystal structure determination and antiproliferative activity. / Ivanovic, Ivanka; Gligorijevic, Nevenka; Arandelovic, Sandra et al.
In: Polyhedron, Vol. 61, 18.09.2013, p. 112-118.

Publications: Contribution to journalArticlePeer Reviewed


Differences and similarities between symmetrically and unsymmetrically substituted PtIV complexes with N,(N)-(di)alkylethane-1,2-diamine ligands. / Pichler, Verena; Galanski, Mathea Sophia; Keppler, Bernhard.
2013. Paper presented at 1st International Symposium on Functional Metal Complexes that Bind to Biomolecules (second Whole Action Meeting of the COST Action CM1105) , Barcelona, Spain.

Publications: Contribution to conferencePaper


p53 Increases Intra-Cellular Calcium Release by Transcriptional Regulation of Calcium Channel TRPC6 in GaQ(3)-Treated Cancer Cells. / Madan, Esha; Gogna, Rajan (Corresponding author); Keppler, Bernhard et al.
In: PLoS ONE, Vol. 8, No. 8, 71016, 16.08.2013.

Publications: Contribution to journalArticlePeer Reviewed


A systematic capillary electrophoresis study on the effect of the buffer composition on the reactivity of the anticancer drug cisplatin to the DNA model 2 '-deoxyguanosine 5'-monophosphate (dGMP). / Grabmann, Gerlinde; Keppler, Bernhard K.; Hartinger, Christian G. (Corresponding author).
In: Analytical and Bioanalytical Chemistry, Vol. 405, No. 20, 08.2013, p. 6417-6424.

Publications: Contribution to journalArticlePeer Reviewed


Bulky N(,N)-(Di)alkylethane-1,2-diamineplatinum(II) Compounds as Precursors for Generating Unsymmetrically Substituted Platinum(IV) Complexes. / Pichler, Verena; Goeschl, Simone; Meier, Samuel M. et al.
In: Inorganic Chemistry, Vol. 52, No. 14, 15.07.2013, p. 8151-8162.

Publications: Contribution to journalArticlePeer Reviewed


Identification of the Structural Determinants for Anticancer Activity of a Ruthenium Arene Peptide Conjugate. / Meier, Samuel M.; Novak, Maria; Kandioller, Wolfgang et al.
In: Chemistry: A European Journal, Vol. 19, No. 28, 08.07.2013, p. 9297-9307.

Publications: Contribution to journalArticlePeer Reviewed


Rhodium(Cp*) Compounds with Flavone-derived Ligand Systems: Synthesis and Characterization. / Schwarz, Martina B.; Kurzwernhart, Andrea; Roller, Alexander et al.
In: Zeitschrift für Anorganische und Allgemeine Chemie, Vol. 639, No. 8-9, 07.2013, p. 1648-1654.

Publications: Contribution to journalArticlePeer Reviewed


The Aqueous Chemistry of Pt(II) Complexes under Physiologically Relevant Conditions Studied by Means of CZE–UV and CZE–ESI-MS. / Grabmann, Gerlinde; Meier, Samuel Matthias; Scaffidi-Domianello, Yulia et al.
Konferenzband. 2013.

Publications: Contribution to bookContribution to proceedings


The Influence of Buffer Components on the Binding of Cisplatin Toward 5’-dGMP Studied by Means of CZE–UV and CZE–ESI-MS. / Grabmann, Gerlinde; Keppler, Bernhard; Hartinger, Christian G.
Konferenzband. 2013.

Publications: Contribution to bookContribution to proceedings


Natural organic matter and iron export from the Tanner Moor, Austria. / Jirsa, Franz (Corresponding author); Neubauer, Elisabeth; Kittinger, Richard et al.
In: Limnologica, Vol. 43, No. 4, 01.06.2013, p. 239-244.

Publications: Contribution to journalArticlePeer Reviewed


Am(m)ines Make the Difference: Organoruthenium Am(m)ine Complexes and Their Chemistry in Anticancer Drug Development. / Babak, Maria; Meier, Samuel Matthias; Legin, Anton et al.
In: Chemistry: A European Journal, Vol. 19, No. 13, 2013, p. 4308-4318.

Publications: Contribution to journalArticlePeer Reviewed


Characterization of the binding sites of the anticancer ruthenium(III) complexes KP1019 and KP1339 on human serum albumin via competition studies. / Domotor, Orsolya; Hartinger, Christian G.; Bytzek, Anna et al.
In: Journal of Biological Inorganic Chemistry, Vol. 18, No. 1, 2013, p. 9-17.

Publications: Contribution to journalArticlePeer Reviewed


Copper(II) complexes with derivatives of pyrazole as potential antioxidant enzyme mimics. / Kupcewicz, Bogumila (Corresponding author); Sobiesiak, Krzysztof; Malinowska, Katarzyna et al.
In: Medicinal Chemistry Research: an international journal for rapid communications on design and mechanisms of action of biologically active agents, Vol. 22, No. 5, 2013, p. 2395-2402.

Publications: Contribution to journalArticlePeer Reviewed


Influence of extracellular pH on the cytotoxicity, cellular accumulation, and DNA interaction of novel pH-sensitive 2-aminoalcoholatoplatinum(II) complexes. / Valiahdi, Seied Mojtaba; Egger, Alexander; Miklos, Walter et al.
In: Journal of Biological Inorganic Chemistry, Vol. 18, No. 2, 2013, p. 249-260.

Publications: Contribution to journalArticlePeer Reviewed


Maleimide-functionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery. / Pichler, Verena; Mayr, Josef; Heffeter, Petra (Corresponding author) et al.
In: Chemical Communications, Vol. 49, No. 22, 2013, p. 2249-2251.

Publications: Contribution to journalArticlePeer Reviewed


Metal-Arene Complexes with Indolo[3,2-c]-quinolines: Effects of Ruthenium vs Osmium and Modifications of the Lactam Unit on Intermolecular Interactions, Anticancer Activity, Cell Cycle, and Cellular Accumulation. / Filak, Lukas; Göschl, Simone; Heffeter, Petra et al.
In: Organometallics, Vol. 32, No. 3, 2013, p. 903-914.

Publications: Contribution to journalArticlePeer Reviewed