o. Univ.-Prof. Dr. Dr. Bernhard Keppler

Email: bernhard.keppler@univie.ac.at
Phone: +43-1-4277-52602

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Publications


Novel (thio)pyrone-derived organometallics with anticancer properties. / Schmidlehner, Melanie; Flocke, Lea Sophia Elise; Hejl, Michaela et al.
Book of Abstracts. 2015. p. MS-34.

Publications: Contribution to bookContribution to proceedings


Speciation of metal-based nanomaterials in human serum characterized by capillary electrophoresis coupled to ICP-MS: a case study of gold nanoparticles. / Matczuk, Magdalena; Anecka, Karolina; Scaletti, Federica et al.
In: Metallomics: integrated biometal science, Vol. 7, No. 9, 01.09.2015, p. 1364-1370.

Publications: Contribution to journalArticlePeer Reviewed


Molecular mode of action of NKP-1339-a clinically investigated ruthenium-based drug - involves Nrf2 translocation and ER-associated protein degradation in colon carcinoma cell lines. / Flocke, L. S.; Trondl, R.; Bamonti, L. et al.
In: European Journal of Cancer, Vol. 51, 09.2015, p. S59-S59.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Multiscale distribution of anticancer platinum(IV) complexes in murine samples revealed by combination of NanoSIMS, LA-ICP-MS and TEM imaging. / Legin, A.; Theiner, S.; Schintlmeister, A. et al.
In: European Journal of Cancer, Vol. 51, 09.2015, p. S128-S128.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Targeting DNA topoisomerase II alpha activity with thiomaltol-based organometallic complexes. / Novak, M.; Hackl, C.; Kandioller, W. et al.
In: European Journal of Cancer, Vol. 51, 09.2015, p. S73-S73.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


River-derived humic substances as iron chelators in seawater. / Krachler, Regina (Corresponding author); Krachler, Rudolf F.; Wallner, Gabriele et al.
In: Marine Chemistry, Vol. 174, 20.08.2015, p. 85-93.

Publications: Contribution to journalArticlePeer Reviewed


Investigation of factors involved in the hypersensitivity to KP1339-treatment. / Alte, Beatrix; Pirker, Christine; Mohr, Thomas et al.
In: Cancer Research, Vol. 75, 01.08.2015.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Preclinical development of a novel hypoxia-activated EGFR inhibitor using a cobalt(III)-based prodrug design. / Heffeter, Petra; Karnthaler-Benbakka, Claudia; Groza, Diana et al.
In: Cancer Research, Vol. 75, 01.08.2015.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Tumor microenvironment in focus: LA-ICP-MS bioimaging of a preclinical tumor model upon treatment with platinum(IV)-based anticancer agents. / Theiner, Sarah; Kornauth, Christoph; Varbanov, Hristo P. et al.
In: Metallomics: integrated biometal science, Vol. 7, No. 8, 01.08.2015, p. 1256-1264.

Publications: Contribution to journalArticlePeer Reviewed


Three-dimensional and co-culture models for preclinical evaluation of metal-based anticancer drugs. / Schreiber-Brynzak, Ekaterina; Klapproth, Erik; Unger, Christine et al.
In: Investigational New Drugs: the journal of new anti-cancer agents, Vol. 33, No. 4, 08.2015, p. 835-847.

Publications: Contribution to journalArticlePeer Reviewed


From the selective delivery of organometallic anticancer drugs to targeted therapy and target identification. / Hanif, Muhammad; Moon, Sally; Babak, Maria et al.
Book of Abstracts. 2015. p. 166.

Publications: Contribution to bookContribution to proceedings


Combination of Cadmium and High Cholesterol Levels as a Risk Factor for Heart Fibrosis. / Tuerkcan, Adrian; Scharinger, Bernhard; Grabmann, Gerlinde et al.
In: Toxicological Sciences, Vol. 145, No. 2, 06.2015, p. 360-371.

Publications: Contribution to journalArticlePeer Reviewed



Triapine-mediated ABCB1 induction via PKC induces widespread therapy unresponsiveness but is not underlying acquired triapine resistance. / Miklos, W.; Pelivan, K.; Kowol, C. R. et al.
In: Cancer Letters, Vol. 361, No. 1, 28.05.2015, p. 112-120.

Publications: Contribution to journalArticlePeer Reviewed


Organometallic complexes of (thio)allomaltol-based Mannich-products: Synthesis, stability and preliminary biological investigations. / Schmidlehner, Melanie; Pichler, Verena; Roller, Alexander et al.
In: Journal of Organometallic Chemistry, Vol. 782, 15.04.2015, p. 69-76.

Publications: Contribution to journalArticlePeer Reviewed


Bis- and Tetrakis(carboxylato)platinum(IV) Complexes with Mixed Axial Ligands - Synthesis, Characterization, and Cytotoxicity. / Hoffmeister, Bjoern R.; Hejl, Michaela; Adib-Razavi, Mahsa S. et al.
In: Chemistry & Biodiversity, Vol. 12, No. 4, 04.2015, p. 559-574.

Publications: Contribution to journalArticlePeer Reviewed


Bis- and Tris(carboxylato)platinum(IV) Complexes with Mixed Am(m)ine Ligands in the trans Position Exhibiting Exceptionally High Cytotoxicity. / Hoffmeister, Bjoern R.; Hejl, Michaela; Jakupec, Michael A. et al.
In: European Journal of Inorganic Chemistry, Vol. 2015, No. 10, 04.2015, p. 1700-1708.

Publications: Contribution to journalArticlePeer Reviewed


Half-Sandwich Ruthenium(II) Biotin Conjugates as Biological Vectors to Cancer Cells. / Babak, Maria V.; Plazuk, Damian; Meier, Samuel M. et al.
In: Chemistry: A European Journal, Vol. 21, No. 13, 23.03.2015, p. 5110-5117.

Publications: Contribution to journalArticlePeer Reviewed