o. Univ.-Prof. Dr. Dr. Bernhard Keppler

Email: bernhard.keppler@univie.ac.at
Phone: +43-1-4277-52602

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Publications


An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For Plectin. / Meier, Samuel M. (Corresponding author); Kreutz, Dominique; Winter, Lilli et al.
In: Angewandte Chemie (International Edition), Vol. 56, No. 28, 03.07.2017, p. 8267-8271.

Publications: Contribution to journalArticlePeer Reviewed


Antiproliferative Copper(II) and Platinum(II) Complexes with Bidentate N,N-Donor Ligands. / Sommerfeld, Nadine S.; Guelzow, Jana; Roller, Alexander et al.
In: European Journal of Inorganic Chemistry, Vol. 2017, No. 24, 30.06.2017, p. 3115-3124.

Publications: Contribution to journalArticlePeer Reviewed


Electochemical activation of platinum based cytostatics investigated by means of liquid chromatography and mass spectrometry. / Frensemeier, Lisa ; Köllensperger, Gunda; Kowol, Christian et al.
Book of Abstracts. ed. / Michal Holcapec. 2017.

Publications: Contribution to bookContribution to proceedings


MONOMALEIMIDE-FUNCTIONALIZED PLATINUM COMPOUNDS FOR CANCER THERAPY. / Kowol, Christian (Inventor); Heffeter, Petra (Inventor); Berger, Walter (Inventor) et al.
Patent No.: WO2017097986 A1. Jun 15, 2017.

Publications: Patent


Understanding the metabolism of the anticancer drug Triapine using electrochemistry and liquid chromatography coupled to mass spectrometry (EC/LC/MS). / Pelivan, Karla; Frensemeier, Lisa ; Karst, Uwe et al.
Conference Proceedings . 2017.

Publications: Contribution to bookContribution to proceedings


EGFR-targeting peptide-coupled platinum(IV) complexes. / Mayr, Josef; Hager, Sonja; Koblmueller, Bettina et al.
In: Journal of Biological Inorganic Chemistry, Vol. 22, No. 4, 06.2017, p. 591-603.

Publications: Contribution to journalArticlePeer Reviewed


Functionalization of ruthenium(II)(ų 6-p-cymene)(3-hydroxy-2-pyridone) complexes with (thio)morpholine: Synthesis and Bioanalytical Studies. / Hanif, Muhammad; Meier, Samuel M.; Adhireksan, Zenita et al.
In: Chempluschem, Vol. 82, No. 6, 06.2017, p. 841-847.

Publications: Contribution to journalArticlePeer Reviewed


Distinct activity of the bone-targeted gallium compound KP46 against osteosarcoma cells - synergism with autophagy inhibition. / Kubista, Bernd; Schoefl, Thomas; Mayr, Lisa et al.
In: Journal of Experimental and Clinical Cancer Research, Vol. 36, No. 1, 52, 12.04.2017.

Publications: Contribution to journalArticlePeer Reviewed


Release of Pt(II) cytostatics from Pt(IV) prodrugs by means of electrochemistry/liquid chromatography/mass spectrometry. / Frensemeier, Lisa ; Köllensperger, Gunda; Kowol, Christian et al.
Book of Abstracts. ed. / M. Lämmerhofer; C. Huhn. 2017.

Publications: Contribution to bookContribution to proceedings


Application of imaging mass spectrometry approaches to facilitate metal-based anticancer drug research. / Lee, Ronald F. S.; Theiner, Sarah; Meibom, Anders et al.
In: Metallomics: integrated biometal science, Vol. 9, No. 4, 01.04.2017, p. 365-381.

Publications: Contribution to journalArticlePeer Reviewed


Enhancing the Cytotoxic Activity of Anticancer Pt-IV Complexes by Introduction of Lonidamine as an Axial Ligand. / Nosova, Yulia N.; Foteeva, Lidia S.; Zenin, Ilia V. et al.
In: European Journal of Inorganic Chemistry, Vol. 2017, No. 12, 27.03.2017, p. 1785-1791.

Publications: Contribution to journalArticlePeer Reviewed


Low-Generation Polyamidoamine Dendrimers as Drug Carriers for Platinum(IV) Complexes. / Sommerfeld, Nadine S.; Hejl, Michaela; Klose, Matthias H. M. et al.
In: European Journal of Inorganic Chemistry, Vol. 2017, No. 12, 27.03.2017, p. 1713-1720.

Publications: Contribution to journalArticlePeer Reviewed


Electrochemistry coupled to LC/MS for the investigation of reductive and oxidative metabolic reactions of drug substances. / Frensemeier, Lisa ; Köllensperger, Gunda; Kowol, Christian et al.
2017. Paper presented at 4th International Workshop on Electrochemistry/Mass Spectrometry, Münster, Germany.

Publications: Contribution to conferencePaper


Comparative studies of oxaliplatin-based platinum(IV) complexes in different in vitro and in vivo tumor models. / Goeschl, Simone; Schreiber-Brynzak, Ekaterina; Pichler, Verena et al.
In: Metallomics: integrated biometal science, Vol. 9, No. 3, 22.03.2017, p. 309-322.

Publications: Contribution to journalArticlePeer Reviewed


{Ru(CO)(x)}-Core complexes with benzimidazole ligands: synthesis, X-ray structure and evaluation of anticancer activity in vivo. / Tamasi, Gabriella (Corresponding author); Merlino, Antonello; Scaletti, Federica et al.
In: Dalton Transactions, Vol. 46, No. 9, 07.03.2017, p. 3025-3040.

Publications: Contribution to journalArticlePeer Reviewed


Electrochemical conversion of Pt(IV) prodrugs to Pt(II) cytostatics investigated by means of liquid chromatography and mass spectrometry. / Frensemeier, Lisa ; Köllensperger, Gunda; Kowol, Christian et al.
2017. Paper presented at Jahrestagung der Deutschen Gesellschaft für Massenspektrometrie (DGMS) 2017, Kiel, Germany.

Publications: Contribution to conferencePaper


An albumin-based tumor-targeted oxaliplatin prodrug with distinctly improved anticancer activity in vivo. / Mayr, Josef; Heffeter, Petra (Corresponding author); Groza, Diana et al.
In: Chemical Science, Vol. 8, No. 3, 01.03.2017, p. 2241-2250.

Publications: Contribution to journalArticlePeer Reviewed


Heavy metals in the mallard Anas platyrhynchos from eastern Austria. / Plessl, Christof; Jandrisits, Peter; Krachler, Regina et al.
In: Science of the Total Environment, Vol. 580, 15.02.2017, p. 670-676.

Publications: Contribution to journalArticlePeer Reviewed


Task-specific thioglycolate ionic liquids for heavy metal extraction: Synthesis, extraction efficacies and recycling properties. / Platzer, Sonja; Kar, Mega; Leyma, Raphlin et al.
In: Journal of Hazardous Materials, Vol. 324, No. Part B, 15.02.2017, p. 241-249.

Publications: Contribution to journalArticlePeer Reviewed