o. Univ.-Prof. Dr. Dr. Bernhard Keppler

Email: bernhard.keppler@univie.ac.at
Phone: +43-1-4277-52602

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Publications


Preclinical characterization of anticancer gallium(III) complexes: solubility, stability, lipophilicity and binding to serum proteins. / Timerbaev, Andrei (Corresponding author); Rudnev, Alexander V.; Foteeva, Lidia S. et al.
In: Journal of Inorganic Biochemistry, Vol. 100, No. 11, 2006, p. 1819-1826.

Publications: Contribution to journalArticlePeer Reviewed


Redox behavior of tumor-inhibiting ruthenium(III) complexes and effects of physiological reductants on their binding to GMP. / Schluga, Petra; Hartinger, Christian (Corresponding author); Egger, Alexander et al.
In: Dalton Transactions, Vol. 14, 2006, p. 1796-1802.

Publications: Contribution to journalArticlePeer Reviewed


Ruthenium(III)-arene complex with heterocyclic ligands as prospective antitumor agent. / John, Roland; Arion, Vladimir; Jakupec, Michael et al.
Proceedings of the 9th International Symposium on Metal Ions in Biology and Medicine: held in Lisboa, Portugal, Europe on May 21 - 24, 2006. ed. / Maria Carmen Alpiom. Vol. 9 Paris: John Libbey Eurotext, 2006. p. 40-46 (Metal ions in biology and medicine).

Publications: Contribution to bookContribution to proceedings


Synthesis and characterization of [(1R,2R)-trans-diaminocyclohexane]- platinum(II) coordinated to sulfur and selenium amino acids. / Rothenburger, Claudia; Galanski, Mathea Sophia (Corresponding author); Arion, Vladimir et al.
In: European Journal of Inorganic Chemistry, No. 18, 2006, p. 3746-3752.

Publications: Contribution to journalArticlePeer Reviewed


Synthesis and In Vitro Antitumor Activity of 2,3-Diaminoglucose-Based Platinum(II) Coordination Compounds. / Berger, Isabella; Nazarov, Alexey; Hartinger, Christian et al.
Proceedings of the 9th International Symposium on Metal Ions in Biology and Medicine: held in Lisboa, Portugal, Europe on May 21 - 24, 2006. ed. / Carmen Alpoim. Vol. 9 Paris [u.a.]: John Libbey Eurotext, 2006. p. 9-12 (Metal ions in biology and medicine).

Publications: Contribution to bookContribution to proceedings


The Binding of Ruthenium(III) Anticancer Complexes to Serum Proteins: an ESI-MS Study. / Größl, Michael; Hartinger, Christian; Egger, Alexander et al.
Proceedings of the 9th International Symposium on Metal Ions in Biology and Medicine: held in Lisboa, Portugal, Europe on May 21 - 24, 2006. ed. / M. C Alpoim; P. V. Morais; M. A. Santos; A. J. Cristovao; Centeno. J.; P. Collery. Vol. 9 Paris: John Libbey Eurotext, 2006. p. 111-116 (Metal ions in biology and medicine).

Publications: Contribution to bookContribution to proceedings


The First Metal-Based Paullone Derivative with High Antiproliferative Activity in Vitro. / Dobrov, Anatolie; Arion, Vladimir (Corresponding author); Kandler, Norbert et al.
In: Inorganic Chemistry, Vol. 45, No. 5, 2006, p. 1945-1950.

Publications: Contribution to journalArticlePeer Reviewed


Tris(8-quinolinolato)gallium(III) exerts strong antiproliferative effects in melanoma cells. / Valiahdi, Seied Mojtaba; Jakupec, Michael; Marculescu, Rodrig et al.
Metal Ions in Biology and Medicin. Unknown publisher, 2006. p. 282-286.

Publications: Contribution to bookChapter


Tumorhemmende Metallverbindungen. / Galanski, Mathea Sophia; Keppler, Bernhard.
In: Pharmazie in Unserer Zeit, Vol. 35, No. 2, 2006, p. 118-123.

Publications: Contribution to journalArticlePeer Reviewed


Analysis of anticancer platinum(II)-complexes by microemulsion electrokinetic chromatography: Separation of diastereomers and estimation of octanol-water partition coefficients. / Rappel, Christina; Galanski, Mathea Sophia; Yasemi, Afshin et al.
In: Electrophoresis, Vol. 26, No. 4-5, 2005, p. 878-884.

Publications: Contribution to journalArticlePeer Reviewed


Bis- and tris-bicyclophosphites of d-glucofuranoside. Unexpected catalysis of P(III/V)-oxidation by triethylamine. / Nazarov, Alexey (Corresponding author); Koroteev, Mikhail P.; Hartinger, Christian et al.
In: Tetrahedron, Vol. 61, No. 46, 2005, p. 10943-10950.

Publications: Contribution to journalArticlePeer Reviewed


Comparative binding of antitumor indazolium [trans-tetrachlorobis(1H- indazole)ruthenate(III)] to serum transport proteins assayed by capillary zone electrophoresis. / Timerbaev, Andrei (Corresponding author); Rudnev, Alexander V.; Semenova, Olga et al.
In: Analytical Biochemistry, Vol. 341, No. 2, 2005, p. 326-333.

Publications: Contribution to journalArticlePeer Reviewed


Design, synthesis, physical and chemical characterisation, and biological interactions of lectin-targeted latex nanoparticles bearing Gd-DTPA chelates: An exploration of magnetic resonance molecular imaging (MRMI). / Pashkunova-Martic, Irena; Mistlberger, Klaudia; Shcherbakova, Nadezhda et al.
In: Histochemistry and Cell Biology, Vol. 123, No. 3, 2005, p. 283-301.

Publications: Contribution to journalArticlePeer Reviewed


Determination of binding constants and stoichiometries for platinum anticancer drugs and serum transport proteins by capillary electrophoresis using the Hummel-Dreyer method. / Rudnev, Alexander V.; Aleksenko, Svetlana S.; Semenova, Olga et al.
In: Journal of Separation Science, Vol. 28, No. 2, 2005, p. 121-127.

Publications: Contribution to journalArticlePeer Reviewed


Glucose ferrocenyl-oxazolines: Coordination behavior toward [Pd(?3-allyl)Cl]2 studied by ESI-MS. / Hartinger, Christian; Nazarov, Alexey; Galanski, Mathea Sophia et al.
In: Journal of Organometallic Chemistry, Vol. 690, No. 14, 2005, p. 3301-3308.

Publications: Contribution to journalArticlePeer Reviewed


Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells. / Kapitza, S; Pongratz, Martina; Jakupec, Michael et al.
In: Journal of Cancer Research and Clinical Oncology, Vol. 131, No. 2, 2005, p. 101-110.

Publications: Contribution to journalArticlePeer Reviewed


Interactions of a novel ruthenium-based anticancer drug (KP1019 or FFC14a) with serum proteins - Significance for the patient. / Hartinger, Christian; Hann, Stephan; Köllensperger, Gunda et al.
In: International Journal of Clinical Pharmacology and Therapeutics, Vol. 43, No. 12, 2005, p. 583-585.

Publications: Contribution to journalArticlePeer Reviewed


Intrinsic and acquired forms of resistance against the anticancer ruthenium compound KP1019 [indazolium trans-[tetrachlorobis(1H-indazole)ruthenate (III)] (FFC14A). / Heffeter, Petra; Pongratz, Martina; Steiner, Elisabeth et al.
In: Journal of Pharmacology and Experimental Therapeutics, Vol. 312, No. 1, 2005, p. 281-289.

Publications: Contribution to journalArticlePeer Reviewed