o. Univ.-Prof. Dr. Dr. Bernhard Keppler

Email: bernhard.keppler@univie.ac.at
Phone: +43-1-4277-52602

» CV
» Publications

Publications


Structure elucidation and quantification of the reduction products of anticancer Pt(iv) prodrugs by electrochemistry/mass spectrometry (EC-MS). / Frensemeier, L. M.; Mayr, J.; Koellensperger, G. et al.
In: The Analyst, Vol. 143, No. 9, 07.05.2018, p. 1997-2001.

Publications: Contribution to journalArticlePeer Reviewed


Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA. / Kiakos, Konstantinos (Corresponding author); Englinger, Bernhard; Yanow, Stephanie K. et al.
In: Bioorganic & Medicinal Chemistry Letters, Vol. 28, No. 8, 01.05.2018, p. 1342-1347.

Publications: Contribution to journalArticlePeer Reviewed


The impact of whole human blood on the kinetic inertness of platinum(IV) prodrugs - an HPLC-ICP-MS study. / Theiner, Sarah; Grabarics, Marko; Galvez, Luis et al.
In: Dalton Transactions, Vol. 47, No. 15, 21.04.2018, p. 5252-5258.

Publications: Contribution to journalArticlePeer Reviewed


N- and S-donor leaving groups in triazole-based ruthena(II) cycles: potent anticancer activity, selective activation, and mode of action studies. / Riedl, Christoph A.; Hejl, Michaela; Klose, Matthias H. M. et al.
In: Dalton Transactions, Vol. 47, No. 13, 07.04.2018, p. 4625-4638.

Publications: Contribution to journalArticlePeer Reviewed


Rollover Cyclometalated Bipyridine Platinum Complexes as Potent Anticancer Agents: Impact of the Ancillary Ligands on the Mode of Action. / Babak, Maria V. (Corresponding author); Pfaffeneder-Kmen, Martin; Meier-Menches, Samuel M. et al.
In: Inorganic Chemistry, Vol. 57, No. 5, 05.03.2018, p. 2851-2864.

Publications: Contribution to journalArticlePeer Reviewed


A comparative study of α-N-pyridyl thiosemicarbazones: Spectroscopic properties, solution stability and copper(II) complexation. / Domotor, Orsolya; May, Nora V.; Pelivan, Karla et al.
In: Inorganica Chimica Acta, Vol. 472, 01.03.2018, p. 264-275.

Publications: Contribution to journalArticlePeer Reviewed


Bioimaging of isosteric osmium and ruthenium anticancer agents by LA-ICP-MS. / Klose, Matthias H. M.; Theiner, Sarah; Kornauth, Christoph et al.
In: Metallomics: integrated biometal science, Vol. 10, No. 3, 01.03.2018, p. 388-396.

Publications: Contribution to journalArticlePeer Reviewed


Complexes of pyridoxal thiosemicarbazones formed with vanadium(IV/V) and copper(II): Solution equilibrium and structure. / Jakusch, Tamas (Corresponding author); Kozma, Karoly; Enyedy, Eva A. et al.
In: Inorganica Chimica Acta, Vol. 472, 01.03.2018, p. 243-253.

Publications: Contribution to journalArticlePeer Reviewed


Comparison of metabolic pathways of different alpha-N-heterocyclic thiosemicarbazones. / Pelivan, Karla; Frensemeier, Lisa M.; Karst, Uwe et al.
In: Analytical and Bioanalytical Chemistry, Vol. 410, No. 9, 03.2018, p. 2343-2361.

Publications: Contribution to journalArticlePeer Reviewed


Bacterial ghosts as adjuvant to oxaliplatin chemotherapy in colorectal carcinomatosis. / Groza, Diana; Gehrig, Sebastian; Kudela, Pavol et al.
In: OncoImmunology, Vol. 7, No. 5, e1424676, 16.02.2018.

Publications: Contribution to journalArticlePeer Reviewed


Structure-activity relationships for ruthenium and osmium anticancer agents - towards clinical development. / Meier-Menches, Samuel M. (Corresponding author); Gerner, Christopher; Berger, Walter et al.
In: Chemical Society Reviews, Vol. 47, No. 3, 07.02.2018, p. 909-928.

Publications: Contribution to journalReviewPeer Reviewed


Studies of KP46 and KP1019 and the Hydrolysis Product of KP1019 in Lipiodol Emulsions: Preparation and Initial Characterizations as Potential Theragnostic Agents. / Pashkunova-Martic, Irena (Corresponding author); Losantos, Berta Cebrian; Kandler, Norbert et al.
In: Current Drug Delivery , Vol. 15, No. 1, 2018, p. 134-142.

Publications: Contribution to journalArticlePeer Reviewed


Update on NKP-1339/IT-139, a ruthenium-based GRP78 inhibitor in clinical development. / Schoenhacker-Alte, B.; Baier, D.; Mohr, T. et al.
In: Oncology Research and Treatment, Vol. 41, No. Supplement 1, 2018, p. 47-48.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Maleimide-bearing oxaliplatin(IV) complexes with outstanding antitumor activity in vivo. / Fronik, Philipp; Mayr, Josef; Heffeter, Petra et al.
Book of Abstracts. 2017.

Publications: Contribution to bookContribution to proceedings


Fast High-Resolution Laser Ablation-Inductively Coupled Plasma Mass Spectrometry Imaging of the Distribution of Platinum-Based Anticancer Compounds in Multicellular Tumor Spheroids. / Theiner, Sarah; Van Malderen, Stijn J. M.; Van Acker, Thibaut et al.
In: Analytical Chemistry, Vol. 89, No. 23, 05.12.2017, p. 12641-12645.

Publications: Contribution to journalArticlePeer Reviewed


Trends and Perspectives of Ruthenium Anticancer Compounds (Non-PDT). / Jakupec, Michael; Kandioller, Wolfgang; Schönhacker-Alte, Beatrix et al.
Ruthenium Complexes: Photochemical and Biomedical Applications. ed. / Wesley R Browne; Alvin A Holder; Mark A Lawrence; Jimmie L Bullock Jr; Lothar Lilge. Wiley Online Library, 2017. p. 271-291.

Publications: Contribution to bookChapterPeer Reviewed


beta-O-4 type dilignol compounds and their iron complexes for modeling of iron binding to humic acids: synthesis, characterization, electrochemical studies and algal growth experiments. / Orlowska, Ewelina; Enyedy, Eva A.; Pignitter, Marc et al.
In: New Journal of Chemistry, Vol. 41, No. 20, 21.10.2017, p. 11546-11555.

Publications: Contribution to journalArticlePeer Reviewed


Thioglycolate-based task-specific ionic liquids: Metal extraction abilities vs acute algal toxicity. / Platzer, Sonja; Leyma, Raphlin; Wolske, Sara et al.
In: Journal of Hazardous Materials, Vol. 340, 15.10.2017, p. 113-119.

Publications: Contribution to journalArticlePeer Reviewed


Comparative equilibrium and structural studies of new pentamethylcyclopentadienyl rhodium complexes bearing (O, N) donor bidentate ligands. / Domotor, Orsolya; Hackl, Carmen M.; Bali, Krisztina et al.
In: Journal of Organometallic Chemistry, Vol. 846, 01.10.2017, p. 287-295.

Publications: Contribution to journalArticlePeer Reviewed


Sensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasis. / Schoenhacker-Alte, Beatrix; Mohr, Thomas; Pirker, Christine et al.
In: Cancer Letters, Vol. 404, 28.09.2017, p. 79-88.

Publications: Contribution to journalArticlePeer Reviewed