o. Univ.-Prof. Dr. Dr. Bernhard Keppler

Email: bernhard.keppler@univie.ac.at
Phone: +43-1-4277-52602

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Publications



A Novel Class of Bis- and Tris-Chelate Diam(m)inebis(dicarboxylato)platinum(IV) Complexes as Potential Anticancer Prodrugs. / Varbanov, Hristo P. (Corresponding author); Goeschl, Simone; Heffeter, Petra et al.
In: Journal of Medicinal Chemistry, Vol. 57, No. 15, 14.08.2014, p. 6751-6764.

Publications: Contribution to journalArticlePeer Reviewed


A cobalt-based strategy for tumor targeting of EGFR-inhibitors. / Karnthaler-Benbakka, Claudia; Groza, Diana; Kryeziu, Kushtrim et al.
In: Journal of Biological Inorganic Chemistry, Vol. 19, 08.2014, p. S803-S803.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Condensation properties of antitumor dinuclear Ru(II) arene complexes with aliphatic linkers: relation to DNA binding and cytotoxicity. / Novakova, Olga; Stankova, Martina; Malina, Jaroslav et al.
In: Journal of Biological Inorganic Chemistry, Vol. 19, 08.2014, p. S816-S816.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Development of potential anticancer agents by coordination of bioactive molecules to organometallic fragments. / Kandioller, Wolfgang; Mokesch, Stephan; Hackl, Carmen et al.
In: Journal of Biological Inorganic Chemistry, Vol. 19, 08.2014, p. S749-S749.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Improved reaction conditions for the synthesis of novel KP1339 derivatives and preliminary investigations on their anticancer potential. / Kuhn, Paul-Steffen; Pichler, Verena; Roller, Alexander et al.
In: Journal of Biological Inorganic Chemistry, Vol. 19, 08.2014, p. S801-S801.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Inductively coupled plasma mass spectrometry for metallodrug development: Albumin binding and serum distribution of cytotoxic cis- and trans-isomeric platinum(II) complexes. / Ossipov, Konstantin; Scaffidi-Domianello, Yulia Y.; Seregina, Irina F. et al.
In: Journal of Inorganic Biochemistry, Vol. 137, 08.2014, p. 40-45.

Publications: Contribution to journalArticlePeer Reviewed


Mixed monodentate tetracarboxylato platinum(IV) complexes featuring a symmetric or unsymmetric coordination sphere. / Hoefer, Doris; Varbanov, Hristo P.; Galanski, Mathea Sophia et al.
In: Journal of Biological Inorganic Chemistry, Vol. 19, 08.2014, p. S784-S784.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Naphthoquinone derivatives as a bioactive ligand scaffold for the development of organometallic metallodrugs. / Hackl, Carmen M.; Jakupec, Michael; Kandioller, Wolfgang et al.
In: Journal of Biological Inorganic Chemistry, Vol. 19, 08.2014, p. S872-S873.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Organometallic anticancer agents. / Moon, Sally; Wiezorek, Stefan; Tong, Kelvin et al.
In: Journal of Biological Inorganic Chemistry, Vol. 19, 08.2014, p. S730-S730.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Recent advances in bioinorganic anticancer drug development. / Keppler, Bernhard K.
In: Journal of Biological Inorganic Chemistry, Vol. 19, 08.2014, p. S713-S713.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Surfactant-mediated activation of the lead anticancer ruthenium compound KP1019 by encapsulation into polymeric nanoparticles. / Fischer, Britta; Heffeter, Petra; Kryeziu, Kushtrim et al.
In: Journal of Biological Inorganic Chemistry, Vol. 19, 08.2014, p. S802-S802.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Synthesis and characterization of bis-maleimide-functionalized platinum(IV) complexes for tumor-targeted drug delivery. / Mayr, Josef; Pichler, Verena; Heffeter, Petra et al.
In: Journal of Biological Inorganic Chemistry, Vol. 19, 08.2014, p. S782-S782.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Synthesis, characterization and anticancer activity of (thio)pyrone-derived organometallic complexes. / Schmidlehner, Melanie; Pichler, Verena; Roller, Alexander et al.
In: Journal of Biological Inorganic Chemistry, Vol. 19, 08.2014, p. S802-S803.

Publications: Contribution to journalMeeting abstract/Conference paperPeer Reviewed


Total Mercury in Sediments, Macrophytes, and Fish from a Shallow Steppe Lake in Eastern Austria. / Jirsa, Franz (Corresponding author); Pirker, Daniel; Krachler, Regina et al.
In: Chemistry & Biodiversity, Vol. 11, No. 8, 08.2014, p. 1263-1275.

Publications: Contribution to journalArticlePeer Reviewed


Alternative cell culture models for preclinical drug screening. / Schreiber-Brynzak, Ekaterina; Klapproth, Erik; Lichtscheidl-Schultz, Irene et al.
Book of Abstracts. 2014. p. 54.

Publications: Contribution to bookContribution to proceedings


Cellular accumulation and redox behavior of novel platinum(IV) compounds. / Göschl, Simone; Varbanov, Hristo; Theiner, Sarah et al.
Book of Abstracts. 2014. p. 62.

Publications: Contribution to bookContribution to proceedings


Efficiently Detecting Metallodrug-Protein Adducts: Ion Trap versus Time-of-Flight Mass Analyzers. / Meier, Samuel M.; Babak, Maria V.; Keppler, Bernhard K. et al.
In: ChemMedChem: chemistry enabling drug discovery, Vol. 9, No. 7, 07.2014, p. 1351-1355.

Publications: Contribution to journalArticlePeer Reviewed


The impact of leaving group variation on the chemical properties and anticancer activity of molybdenocenes. / Reikersdorfer, Marlene; Jakupec, Michael; Malarek, Michael et al.
Book of Abstracts. 2014. p. 73.

Publications: Contribution to bookContribution to proceedingsPeer Reviewed


Topoisomerase IIα targeting activity of half-sandwich ruthenium(II) and rhodium(III) complexes with indan-1,3-dione-derived ligands. / Novak, Maria; Mokesch, Stephan; Kandioller, Wolfgang et al.
Book of Abstracts. 2014. p. 78.

Publications: Contribution to bookContribution to proceedings