o. Univ.-Prof. Dr. Dr. Bernhard Keppler

Email: bernhard.keppler@univie.ac.at
Phone: +43-1-4277-52602

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Publications


Pharmacokinetics of a novel anticancer ruthenium complex (KP1019, FFC14A) in a phase i dose-escalation study. / Lentz, Frederike; Drescher, Anne; Lindauer, Andreas et al.
In: ANTI-CANCER DRUGS, Vol. 20, No. 2, 2009, p. 97-103.

Publications: Contribution to journalArticlePeer Reviewed


Ribonucleotide reductase as one important target of [Tris(1,10- phenanthroline)lanthanum(III)] trithiocyanate (KP772). / Heffeter, Petra; Popovic-Bijelic, Ana; Saiko, Philipp et al.
In: Current Cancer Drug Targets, Vol. 9, No. 5, 2009, p. 595-607.

Publications: Contribution to journalArticlePeer Reviewed


Synthesis and biological studies of some gold(I) complexes containing functionalised alkynes. / Schuh, Esther; Valiahdi, Seied Mojtaba; Jakupec, Michael et al.
In: Dalton Transactions, Vol. 2009, 2009, p. 10841-10845.

Publications: Contribution to journalArticlePeer Reviewed


Synthesis and structures of palladium(II) and platinum(II) complexes containing heterocyclic thiolate ligands formed by cycloaddition reactions of coordinated azides. / Fleischer, Angela; Roller, Alexander; Arion, Vladimir et al.
In: Canadian Journal of Chemistry, Vol. 87, No. 1, 2009, p. 146-150.

Publications: Contribution to journalArticlePeer Reviewed


Synthesis, X-ray diffraction structure, spectroscopic properties and antiproliferative activity of a novel ruthenium complex with constitutional similarity to cisplatin. / Grguric-Sipka, Sanja; Stepanenko, Iryna; Lazic, Jelena M. et al.
In: Dalton Transactions, Vol. 17, 2009, p. 3334-3339.

Publications: Contribution to journalArticlePeer Reviewed


The gallium complex KP46 exerts strong activity against primary explanted melanoma cells and induces apoptosis in melanoma cell lines. / Valiahdi, Seied Mojtaba; Heffeter, Petra; Jakupec, Michael et al.
In: MELANOMA RESEARCH, Vol. 19, No. 5, 2009, p. 283-293.

Publications: Contribution to journalArticlePeer Reviewed


Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity. / Hartinger, Christian; Mendoza Parra, Marco-Antonio; Größl, Michael et al.
In: Journal of Medicinal Chemistry, Vol. 52, No. 4, 2009, p. 916-925.

Publications: Contribution to journalArticlePeer Reviewed


Tuning the anticancer activity of maltol-derived ruthenium complexes by derivatization of the 3-hydroxy-4-pyrone moiety. / Kandioller, Wolfgang; Hartinger, Christian; Nazarov, Alexey et al.
In: Journal of Organometallic Chemistry, Vol. 694, No. 6, 2009, p. 922-929.

Publications: Contribution to journalArticlePeer Reviewed


5-Hydroxy-2-methyl-4H-pyran-4-one. / Shaheen, Muhammad Ashraf; Hartinger, Christian; Tahir, M. Nawaz et al.
In: Acta Crystallographica. Section E: Structure Reports Online, Vol. 65, No. 2, 2009.

Publications: Contribution to journalArticlePeer Reviewed


Application of capillary electrophoresis-inductively coupled plasma mass spectrometry to comparative studying of the reactivity of antitumor ruthenium(III) complexes differing in the nature of counter-ion toward human serum proteins. / Polec-Pawlak, Kasia; Abramski, Jan K.; Ferenc, Julia et al.
In: Journal of Chromatography A, Vol. 1192, No. 2, 30.05.2008, p. 323-326.

Publications: Contribution to journalArticlePeer Reviewed


Preparation and first evaluation of [F-18]FE@SUPPY: a new PET tracer for the adenosine A(3) receptor. / Wadsak, Wolfgang; Mien, Leonhard-Key; Shanab, Karem et al.
In: Nuclear Medicine and Biology, Vol. 35, No. 1, 01.2008, p. 61-66.

Publications: Contribution to journalArticlePeer Reviewed


An electrochemical study of antineoplastic gallium, iron and ruthenium complexes with redox non-innocent alpha-N-heterocyclic chalcogensemicarbazones. / Kowol, Christian; Reisner, Erwin (Corresponding author); Chiorescu, Ion et al.
In: Inorganic Chemistry, Vol. 47, No. 23, 2008, p. 11032-11047.

Publications: Contribution to journalArticlePeer Reviewed


Analysis of quaternary ammonium and phosphonium ionic liquids by reversed-phase high-performance liquid chromatography with charged aerosol detection and unified calibration. / Stojanovic, Anja; Lämmerhofer, Michael (Corresponding author); Kogelnig, Daniel (Corresponding author) et al.
In: Journal of Chromatography A, Vol. 1209, No. 1-2, 2008, p. 179-187.

Publications: Contribution to journalArticlePeer Reviewed


Antitumour metal compounds: more than theme and variations. / Jakupec, Michael (Corresponding author); Galanski, Mathea Sophia; Arion, Vladimir et al.
In: Dalton Transactions, Vol. 2008, No. 2, 2008, p. 183-194.

Publications: Contribution to journalArticlePeer Reviewed


Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: a Novel Approach for the Analysis of Anticancer Metallodrugs in Human Serum and Plasma. / Größl, Michael; Hartinger, Christian (Corresponding author); Polec-Pawlak, Katarzyna et al.
In: Electrophoresis, Vol. 29, No. 10, 2008, p. 2224-2232.

Publications: Contribution to journalArticlePeer Reviewed


Capillary electrophoretic assay for the stability of tris(8-quinolinolato)gallium(III) in tablet formulations. / Keppler, Bernhard; Timerbaev, Andrei (Corresponding author); Stolyarova, Natalya et al.
In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 48, 2008, p. 218-222.

Publications: Contribution to journalArticlePeer Reviewed


Carbohydrate–Metal Complexes and their Potential as Anticancer Agents. / Hartinger, Christian; Nazarov, Alexey; Dyson, Paul J. et al.
In: Current Medicinal Chemistry, Vol. 15, No. 25, 2008, p. 2574-2591.

Publications: Contribution to journalArticlePeer Reviewed


Computational electrochemistry of ruthenium anticancer agents. Unprecedented benchmarking of implicit solvation methods. / Deubel, Dirk (Corresponding author); Chiorescu, Ion; Arion, Vladimir et al.
In: Journal of Chemical Theory and Computation, Vol. 4, 2008, p. 499-506.

Publications: Contribution to journalArticlePeer Reviewed


CZE-ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP. / Größl, Michael; Hartinger, Christian; Dyson, Paul J. et al.
In: Journal of Inorganic Biochemistry, Vol. 102, 2008, p. 1060-1065.

Publications: Contribution to journalArticlePeer Reviewed


Development of new antitumor compounds – new aspects. / Keppler, Bernhard; Jakupec, Michael.
2nd European Conference on Chemistry for Life Sciences. Bologna: Medimond, 2008.

Publications: Contribution to bookContribution to proceedings