Dipl.-Ing. Dr. Wolfgang Kandioller, Senior Scientist­

 

Phone: +43-1-4277-52609
Email: wolfgang.kandioller@univie.ac.at
Währinger Straße 42, Room 2H15

» CV
» Publications
» Teaching 


Research Focus

The research of my group focuses on the following topics for the development of organometallic anticancer agents to overcome the drawbacks of clinically approved platinum-based drugs:

  • Influence of different coordination motifs and organometallic moieties on the anticancer potential
  • Exploiting bioactive ligand scaffolds to design novel metallodrugs with improved anticancer activities
  • Determining the impact of leaving group variation on the physicochemical and biological properties

Team


Alexander Rosner, BSc MSc
Improving the anticancer potency of tridentate naphthoquinone-derived organometallics

Phone: +43-1-4277-52616
Email: alexander.rosner@univie.ac.at
Währinger Straße 42, Room: 2H16

Dipl.-Ing. Paul Getreuer, BSc
Impact of different coordination motifs on the anticancer potential of organometallic complexes

Phone: +43-1-4277-52616
Email: paul.getreuer@univie.ac.at
Währinger Straße 42, Room: 2H16

Former Team Members

  • Heiko Geisler (Master's and PhD student)
    Development of phthiocol-based organometallics with anticancer properties
    Ligand and metal center variation of 2-hydroxy-3-methyl-[1,4]-naphthoquinone-based organometallics
  • Sophia Harringer (PhD student)
    Lead structure optimization for the development of organometallic anticancer drugs
  • Christoph Riedl (Master's and PhD student)
    Investigations on different coordination motifs for the development of novel organometallic anticancer agents
    1,4-disubstituted 1,2,3-triazoles as novel ligand scaffold for the development of organometallic anticancer agents
  • Stephan Mokesch (Master's and PhD student)
    The development of novel anticancer agents with bioactive molecules attached to organometallic fragments
    1,3-Dioxoindan-2-carboxamides as selective O,O-chelating ligands for the development of novel organometallic anticancer drugs
  • Carmen Hackl (Master's and PhD student)
    Leaving-group variation of "piano-stool" complexes for the development of novel organometallic anticancer drugs with targeting properties
    The impact of metal variation of the anticancer activity of thiopyrone-derived complexes
  • Barbara Happl (Master's student)
    Thiopyridone-based organorhodium and -iridium complexes: synthesis, characterization and behavior in aqueous solution
  • Manuel Matzinger (Master's student)
    Establishing selenopyrones as novel ligand scaffold for organometallic anticancer agents
  • Marius Ozenil (Master's student)
    Ru and Os thiopyridone complexes and their instant hydrolysis to thiolato-bridged dimers in aqueous solution
  • Melanie Schmidlehner (PhD student)
    Synthesis, characterization and anticancer activity of metal complexes with (thio)pyrone-derived ligands
  • Marlene Reikersdorfer (Master's student)
    The impact of leaving group variation on the anticancer activity of molybdenocene-based complexes