Publications Institute of Inorganic Chemistry


2007


The complexes [OsCl2(azole)2(dmso)2] and [OsCl2(azole)(dmso)3]: Synthesis, structure, spectroscopic properties and catalytic hydration of chloronitriles. / Stepanenko, Iryna; Cebrian, Berta; Arion, Vladimir et al.
In: European Journal of Inorganic Chemistry, No. 3, 2007, p. 400-411.

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The First Ruthenium-Based Paullones: Syntheses, X-ray Diffraction Structures, and Spectroscopic and Antiproliferative Properties in Vitro. / Schmid, Wolfgang; Zorbas-Seifried, Stefanie; John, Roland et al.
In: Inorganic Chemistry, Vol. 46, No. 9, 2007, p. 3645-3656.

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Two new "onium" fluorosilicates, the products of interaction of fluorosilicic acid with 12-membered macrocycles: Structures and spectroscopic properties. / Gelmboldt, Vladimir O.; Fonari, Marina S.; Simonov, Yurii A. et al.
In: Dalton Transactions, Vol. 27, 2007, p. 2915-2924.

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18F fluoroethylations: different strategies for the rapid translation of 11C-methylated radiotracers. / Wadsak, Wolfgang; Mien, Leonhard-Key; Ettlinger, Dagmar E. et al.
In: Nuclear Medicine and Biology, Vol. 34, No. 8, 2007, p. 1019-1028.

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2006


Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)] trithiocyanate (KP772; FFC24). / Heffeter, Petra; Jakupec, Michael; Körner, Wilfried et al.
In: Biochemical Pharmacology, Vol. 71, No. 4, 2006, p. 426-440.

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Crystal structure of trans-dichloro(dimethylsulfoxide)(diphenylsulfimide)- platinum(II) toluene hemisolvate, PtCl2(C2H 6SO)(C12H10SNH) ž 1/2C7H 8. / Scaffidi-Domianello, Yulia; Haukka, M; Kelly, Paul F et al.
In: Zeitschrift für Kristallographie - New Crystal Structures, Vol. 221, No. 2, 2006, p. 226-228.

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Determination of cisplatin and its hydrolytic metabolite in human serum by capillary electrophoresis techniques. / Huang, Zhuo; Timerbaev, Andrei; Keppler, Bernhard et al.
In: Journal of Chromatography A, Vol. 1106, No. 1-2, 2006, p. 75-79.

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DNA interactions of pH-sensitive, antitumor bis(aminoalcohol) dichloroplatinum(II) complexes. / Zorbas-Seifried, Stefanie; Hartinger, Christian; Meelich, Kristof et al.
In: Biochemistry, Vol. 45, No. 49, 2006, p. 14817-14825.

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Electrospray ionization mass spectrometric study on the coordination behavior of dacarbazine towards transition metal ions. / Hartinger, Christian; Mendoza Parra Ferri, Maria Grazia; Nazarov, Alexey et al.
In: Polyhedron, Vol. 25, No. 9, 2006, p. 1971-1978.

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From bench to bedside - preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A). / Hartinger, Christian; Zorbas-Seifried, Stefanie; Jakupec, Michael et al.
In: Journal of Inorganic Biochemistry, Vol. 100, No. 5-6, 2006, p. 894-904.

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Interactions of antitumor metallodrugs with serum proteins: Advances in characterization using modern analytical methodology. / Timerbaev, Andrei; Hartinger, Christian (Corresponding author); Aleksenko, Svetlana S. et al.
In: Chemical Reviews, Vol. 106, No. 6, 2006, p. 2224-2248.

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Kinetic and Thermodynamic Aspects of the Regioselective Addition of Bifunctional Hydroxylaminooxime-type HO-Nucleophiles to Pt-Complexed Nitriles. / Luzyanin, Konstantin V.; Kukushkin, Vadim Yu; Kuznetsov, Maxim L. et al.
In: Inorganic Chemistry, Vol. 45, No. 5, 2006, p. 2296-2306.

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Metallodrug research and analysis using capillary electrophoresis. / Timerbaev, Andrei; Hartinger, Christian; Keppler, Bernhard.
In: Trends in Analytical Chemistry, Vol. 25, No. 9, 2006, p. 868-875.

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NCA nucleophilic radiofluorination on substituted benzaldehydes for the preparation of [18F]fluorinated aromatic amino acids. / Wadsak, Wolfgang; Wirl-Sagadin, Barbara; Mitterhauser, Markus et al.
In: Applied Radiation and Isotopes, Vol. 64, No. 3, 2006, p. 355-359.

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Platinum group metallodrug-protein binding studies by capillary electrophoresis-inductively coupled plasma-mass spectrometry: a further insight into the reactivity of a novel antitumor ruthenium(III) complex toward human serum proteins. / Polec-Pawlak, Katarzyna; Abramski, Jan K.; Semenova, Olga et al.
In: Electrophoresis, Vol. 27, No. 5-6, 2006, p. 1128-1135.

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Preclinical characterization of anticancer gallium(III) complexes: solubility, stability, lipophilicity and binding to serum proteins. / Timerbaev, Andrei (Corresponding author); Rudnev, Alexander V.; Foteeva, Lidia S. et al.
In: Journal of Inorganic Biochemistry, Vol. 100, No. 11, 2006, p. 1819-1826.

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Recent developments in the field of anticancer platinum complexes. / Galanski, Mathea Sophia (Corresponding author).
In: Recent Patents on Anti-Cancer Drug Discovery, Vol. 1, No. 2, 2006, p. 285-295.

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Redox behavior of tumor-inhibiting ruthenium(III) complexes and effects of physiological reductants on their binding to GMP. / Schluga, Petra; Hartinger, Christian (Corresponding author); Egger, Alexander et al.
In: Dalton Transactions, Vol. 14, 2006, p. 1796-1802.

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Signal separation and determination of the enantiomeric purity of primary amines with (-)-myrtenal - a 13C NMR study. / Dufrasne, Francois; Gelbcke, Michael; Galanski, Mathea Sophia.
In: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Vol. 65, No. 3-4, 2006, p. 869-873.

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The First Metal-Based Paullone Derivative with High Antiproliferative Activity in Vitro. / Dobrov, Anatolie; Arion, Vladimir (Corresponding author); Kandler, Norbert et al.
In: Inorganic Chemistry, Vol. 45, No. 5, 2006, p. 1945-1950.

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Tris(8-quinolinolato)gallium(III) exerts strong antiproliferative effects in melanoma cells. / Valiahdi, Seied Mojtaba; Jakupec, Michael; Marculescu, Rodrig et al.
Metal Ions in Biology and Medicin. Unknown publisher, 2006. p. 282-286.

Publications: Contribution to bookChapter


Tumorhemmende Metallverbindungen. / Galanski, Mathea Sophia; Keppler, Bernhard.
In: Pharmazie in Unserer Zeit, Vol. 35, No. 2, 2006, p. 118-123.

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2005


Analysis of anticancer platinum(II)-complexes by microemulsion electrokinetic chromatography: Separation of diastereomers and estimation of octanol-water partition coefficients. / Rappel, Christina; Galanski, Mathea Sophia; Yasemi, Afshin et al.
In: Electrophoresis, Vol. 26, No. 4-5, 2005, p. 878-884.

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Bis- and tris-bicyclophosphites of d-glucofuranoside. Unexpected catalysis of P(III/V)-oxidation by triethylamine. / Nazarov, Alexey (Corresponding author); Koroteev, Mikhail P.; Hartinger, Christian et al.
In: Tetrahedron, Vol. 61, No. 46, 2005, p. 10943-10950.

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Comparative binding of antitumor indazolium [trans-tetrachlorobis(1H- indazole)ruthenate(III)] to serum transport proteins assayed by capillary zone electrophoresis. / Timerbaev, Andrei (Corresponding author); Rudnev, Alexander V.; Semenova, Olga et al.
In: Analytical Biochemistry, Vol. 341, No. 2, 2005, p. 326-333.

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Determination of binding constants and stoichiometries for platinum anticancer drugs and serum transport proteins by capillary electrophoresis using the Hummel-Dreyer method. / Rudnev, Alexander V.; Aleksenko, Svetlana S.; Semenova, Olga et al.
In: Journal of Separation Science, Vol. 28, No. 2, 2005, p. 121-127.

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Glucose ferrocenyl-oxazolines: Coordination behavior toward [Pd(?3-allyl)Cl]2 studied by ESI-MS. / Hartinger, Christian; Nazarov, Alexey; Galanski, Mathea Sophia et al.
In: Journal of Organometallic Chemistry, Vol. 690, No. 14, 2005, p. 3301-3308.

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Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells. / Kapitza, S; Pongratz, Martina; Jakupec, Michael et al.
In: Journal of Cancer Research and Clinical Oncology, Vol. 131, No. 2, 2005, p. 101-110.

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Interactions of a novel ruthenium-based anticancer drug (KP1019 or FFC14a) with serum proteins - Significance for the patient. / Hartinger, Christian; Hann, Stephan; Köllensperger, Gunda et al.
In: International Journal of Clinical Pharmacology and Therapeutics, Vol. 43, No. 12, 2005, p. 583-585.

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Intrinsic and acquired forms of resistance against the anticancer ruthenium compound KP1019 [indazolium trans-[tetrachlorobis(1H-indazole)ruthenate (III)] (FFC14A). / Heffeter, Petra; Pongratz, Martina; Steiner, Elisabeth et al.
In: Journal of Pharmacology and Experimental Therapeutics, Vol. 312, No. 1, 2005, p. 281-289.

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Isomeric [RuCl2(dmso)2(indazole)2] complexes: Ruthenium(II)-mediated coupling reaction of acetonitrile with 1H-indazole. / Reisner, Erwin; Arion, Vladimir (Corresponding author); Rufinska, Anna et al.
In: Dalton Transactions, No. 14, 2005, p. 2355-2364.

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KP1019 (FFC14A) from bench to bedside: Preclinical and early clinical development - An overview. / Jakupec, Michael; Arion, Vladimir; Kapitza, S et al.
In: International Journal of Clinical Pharmacology and Therapeutics, Vol. 43, No. 12, 2005, p. 595-596.

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On the coordination properties of new bicyclophosphite-carbohydrates. / Nazarov, Alexey; Koroteev, Mikhail P.; Hartinger, Christian et al.
In: Monatshefte für Chemie, Vol. 136, No. 2, 2005, p. 137-146.

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Oxaliplatin and derivatives as anticancer drugs - novel design strategies. / Galanski, Mathea Sophia; Jakupec, Michael; Keppler, Bernhard.
Metal compounds in cancer chemotherapy. ed. / J. M. Pérez; M. A. Fuertes; C. Alonso. Trivandrum, Kerala, India: Research Signpost, 2005. p. 155-185.

Publications: Contribution to bookChapter


Pharmacological properties of cerium compounds. / Jakupec, Michael; Unfried, Peter; Keppler, Bernhard.
In: Reviews of Physiology, Biochemistry and Pharmacology, Vol. 153, No. 1, 2005, p. 101-111.

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Rational development of oxaliplatin analogues - Synthesis and preliminary structure-activity relationships. / Galanski, Mathea Sophia; Habala, Ladislav; Nazarov, Alexey et al.
In: International Journal of Clinical Pharmacology and Therapeutics, Vol. 43, No. 12, 2005, p. 575-576.

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Reactions of potent antitumor complex trans-[RuIIICl 4(indazole)2]- with a DNA-relevant nucleobase and thioethers: Insight into biological action. / Egger, Alexander; Arion, Vladimir (Corresponding author); Reisner, Erwin et al.
In: Inorganic Chemistry, Vol. 44, No. 1, 2005, p. 122-132.

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Redox-active antineoplastic ruthenium complexes with indazole: Correlation of in vitro potency and reduction potential. / Jakupec, Michael; Reisner, Erwin; Eichinger, Anna et al.
In: Journal of Medicinal Chemistry, Vol. 48, No. 8, 2005, p. 2831-2837.

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Synthesis and structure-activity relationships of mono- and dialkyl-substituted oxaliplatin derivatives. / Habala, Ladislav; Galanski, Mathea Sophia; Yasemi, Afshin et al.
In: European Journal of Medicinal Chemistry, Vol. 40, No. 11, 2005, p. 1149-1155.

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Synthesis, cytotoxicity, and structure-activity relationships of new oxaliplatin derivatives. / Galanski, Mathea Sophia (Corresponding author); Yasemi, Afshin; Jakupec, Michael et al.
In: Monatshefte für Chemie, Vol. 136, No. 5, 2005, p. 693-700.

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The heterocyclic ruthenium(III) complex KP1019 (FFC14A) causes DNA damage and oxidative stress in colorectal tumor cells. / Kapitza, S; Jakupec, Michael; Uhl, Maria et al.
In: Cancer Letters, Vol. 226, No. 2, 2005, p. 115-121.

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