Publications Institute of Inorganic Chemistry


2006


Metallodrug research and analysis using capillary electrophoresis. / Timerbaev, Andrei; Hartinger, Christian; Keppler, Bernhard.
In: Trends in Analytical Chemistry, Vol. 25, No. 9, 2006, p. 868-875.

Publications: Contribution to journalArticlePeer Reviewed


NCA nucleophilic radiofluorination on substituted benzaldehydes for the preparation of [18F]fluorinated aromatic amino acids. / Wadsak, Wolfgang; Wirl-Sagadin, Barbara; Mitterhauser, Markus et al.
In: Applied Radiation and Isotopes, Vol. 64, No. 3, 2006, p. 355-359.

Publications: Contribution to journalArticlePeer Reviewed


Platinum group metallodrug-protein binding studies by capillary electrophoresis-inductively coupled plasma-mass spectrometry: a further insight into the reactivity of a novel antitumor ruthenium(III) complex toward human serum proteins. / Polec-Pawlak, Katarzyna; Abramski, Jan K.; Semenova, Olga et al.
In: Electrophoresis, Vol. 27, No. 5-6, 2006, p. 1128-1135.

Publications: Contribution to journalArticlePeer Reviewed


Preclinical characterization of anticancer gallium(III) complexes: solubility, stability, lipophilicity and binding to serum proteins. / Timerbaev, Andrei (Corresponding author); Rudnev, Alexander V.; Foteeva, Lidia S. et al.
In: Journal of Inorganic Biochemistry, Vol. 100, No. 11, 2006, p. 1819-1826.

Publications: Contribution to journalArticlePeer Reviewed


Recent developments in the field of anticancer platinum complexes. / Galanski, Mathea Sophia (Corresponding author).
In: Recent Patents on Anti-Cancer Drug Discovery, Vol. 1, No. 2, 2006, p. 285-295.

Publications: Contribution to journalArticlePeer Reviewed


Redox behavior of tumor-inhibiting ruthenium(III) complexes and effects of physiological reductants on their binding to GMP. / Schluga, Petra; Hartinger, Christian (Corresponding author); Egger, Alexander et al.
In: Dalton Transactions, Vol. 14, 2006, p. 1796-1802.

Publications: Contribution to journalArticlePeer Reviewed


Signal separation and determination of the enantiomeric purity of primary amines with (-)-myrtenal - a 13C NMR study. / Dufrasne, Francois; Gelbcke, Michael; Galanski, Mathea Sophia.
In: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Vol. 65, No. 3-4, 2006, p. 869-873.

Publications: Contribution to journalArticlePeer Reviewed


The First Metal-Based Paullone Derivative with High Antiproliferative Activity in Vitro. / Dobrov, Anatolie; Arion, Vladimir (Corresponding author); Kandler, Norbert et al.
In: Inorganic Chemistry, Vol. 45, No. 5, 2006, p. 1945-1950.

Publications: Contribution to journalArticlePeer Reviewed


Tris(8-quinolinolato)gallium(III) exerts strong antiproliferative effects in melanoma cells. / Valiahdi, Seied Mojtaba; Jakupec, Michael; Marculescu, Rodrig et al.
Metal Ions in Biology and Medicin. Unknown publisher, 2006. p. 282-286.

Publications: Contribution to bookChapter


Tumorhemmende Metallverbindungen. / Galanski, Mathea Sophia; Keppler, Bernhard.
In: Pharmazie in Unserer Zeit, Vol. 35, No. 2, 2006, p. 118-123.

Publications: Contribution to journalArticlePeer Reviewed


2005


Analysis of anticancer platinum(II)-complexes by microemulsion electrokinetic chromatography: Separation of diastereomers and estimation of octanol-water partition coefficients. / Rappel, Christina; Galanski, Mathea Sophia; Yasemi, Afshin et al.
In: Electrophoresis, Vol. 26, No. 4-5, 2005, p. 878-884.

Publications: Contribution to journalArticlePeer Reviewed


Bis- and tris-bicyclophosphites of d-glucofuranoside. Unexpected catalysis of P(III/V)-oxidation by triethylamine. / Nazarov, Alexey (Corresponding author); Koroteev, Mikhail P.; Hartinger, Christian et al.
In: Tetrahedron, Vol. 61, No. 46, 2005, p. 10943-10950.

Publications: Contribution to journalArticlePeer Reviewed


Comparative binding of antitumor indazolium [trans-tetrachlorobis(1H- indazole)ruthenate(III)] to serum transport proteins assayed by capillary zone electrophoresis. / Timerbaev, Andrei (Corresponding author); Rudnev, Alexander V.; Semenova, Olga et al.
In: Analytical Biochemistry, Vol. 341, No. 2, 2005, p. 326-333.

Publications: Contribution to journalArticlePeer Reviewed


Determination of binding constants and stoichiometries for platinum anticancer drugs and serum transport proteins by capillary electrophoresis using the Hummel-Dreyer method. / Rudnev, Alexander V.; Aleksenko, Svetlana S.; Semenova, Olga et al.
In: Journal of Separation Science, Vol. 28, No. 2, 2005, p. 121-127.

Publications: Contribution to journalArticlePeer Reviewed


Glucose ferrocenyl-oxazolines: Coordination behavior toward [Pd(?3-allyl)Cl]2 studied by ESI-MS. / Hartinger, Christian; Nazarov, Alexey; Galanski, Mathea Sophia et al.
In: Journal of Organometallic Chemistry, Vol. 690, No. 14, 2005, p. 3301-3308.

Publications: Contribution to journalArticlePeer Reviewed


Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells. / Kapitza, S; Pongratz, Martina; Jakupec, Michael et al.
In: Journal of Cancer Research and Clinical Oncology, Vol. 131, No. 2, 2005, p. 101-110.

Publications: Contribution to journalArticlePeer Reviewed


Interactions of a novel ruthenium-based anticancer drug (KP1019 or FFC14a) with serum proteins - Significance for the patient. / Hartinger, Christian; Hann, Stephan; Köllensperger, Gunda et al.
In: International Journal of Clinical Pharmacology and Therapeutics, Vol. 43, No. 12, 2005, p. 583-585.

Publications: Contribution to journalArticlePeer Reviewed


Intrinsic and acquired forms of resistance against the anticancer ruthenium compound KP1019 [indazolium trans-[tetrachlorobis(1H-indazole)ruthenate (III)] (FFC14A). / Heffeter, Petra; Pongratz, Martina; Steiner, Elisabeth et al.
In: Journal of Pharmacology and Experimental Therapeutics, Vol. 312, No. 1, 2005, p. 281-289.

Publications: Contribution to journalArticlePeer Reviewed


Isomeric [RuCl2(dmso)2(indazole)2] complexes: Ruthenium(II)-mediated coupling reaction of acetonitrile with 1H-indazole. / Reisner, Erwin; Arion, Vladimir (Corresponding author); Rufinska, Anna et al.
In: Dalton Transactions, No. 14, 2005, p. 2355-2364.

Publications: Contribution to journalArticlePeer Reviewed


KP1019 (FFC14A) from bench to bedside: Preclinical and early clinical development - An overview. / Jakupec, Michael; Arion, Vladimir; Kapitza, S et al.
In: International Journal of Clinical Pharmacology and Therapeutics, Vol. 43, No. 12, 2005, p. 595-596.

Publications: Contribution to journalReviewPeer Reviewed


On the coordination properties of new bicyclophosphite-carbohydrates. / Nazarov, Alexey; Koroteev, Mikhail P.; Hartinger, Christian et al.
In: Monatshefte für Chemie, Vol. 136, No. 2, 2005, p. 137-146.

Publications: Contribution to journalArticlePeer Reviewed


Oxaliplatin and derivatives as anticancer drugs - novel design strategies. / Galanski, Mathea Sophia; Jakupec, Michael; Keppler, Bernhard.
Metal compounds in cancer chemotherapy. ed. / J. M. Pérez; M. A. Fuertes; C. Alonso. Trivandrum, Kerala, India: Research Signpost, 2005. p. 155-185.

Publications: Contribution to bookChapter


Pharmacological properties of cerium compounds. / Jakupec, Michael; Unfried, Peter; Keppler, Bernhard.
In: Reviews of Physiology, Biochemistry and Pharmacology, Vol. 153, No. 1, 2005, p. 101-111.

Publications: Contribution to journalReviewPeer Reviewed


Rational development of oxaliplatin analogues - Synthesis and preliminary structure-activity relationships. / Galanski, Mathea Sophia; Habala, Ladislav; Nazarov, Alexey et al.
In: International Journal of Clinical Pharmacology and Therapeutics, Vol. 43, No. 12, 2005, p. 575-576.

Publications: Contribution to journalArticlePeer Reviewed


Reactions of potent antitumor complex trans-[RuIIICl 4(indazole)2]- with a DNA-relevant nucleobase and thioethers: Insight into biological action. / Egger, Alexander; Arion, Vladimir (Corresponding author); Reisner, Erwin et al.
In: Inorganic Chemistry, Vol. 44, No. 1, 2005, p. 122-132.

Publications: Contribution to journalArticlePeer Reviewed


Redox-active antineoplastic ruthenium complexes with indazole: Correlation of in vitro potency and reduction potential. / Jakupec, Michael; Reisner, Erwin; Eichinger, Anna et al.
In: Journal of Medicinal Chemistry, Vol. 48, No. 8, 2005, p. 2831-2837.

Publications: Contribution to journalArticlePeer Reviewed


Synthesis and structure-activity relationships of mono- and dialkyl-substituted oxaliplatin derivatives. / Habala, Ladislav; Galanski, Mathea Sophia; Yasemi, Afshin et al.
In: European Journal of Medicinal Chemistry, Vol. 40, No. 11, 2005, p. 1149-1155.

Publications: Contribution to journalArticlePeer Reviewed


Synthesis, cytotoxicity, and structure-activity relationships of new oxaliplatin derivatives. / Galanski, Mathea Sophia (Corresponding author); Yasemi, Afshin; Jakupec, Michael et al.
In: Monatshefte für Chemie, Vol. 136, No. 5, 2005, p. 693-700.

Publications: Contribution to journalArticlePeer Reviewed


The heterocyclic ruthenium(III) complex KP1019 (FFC14A) causes DNA damage and oxidative stress in colorectal tumor cells. / Kapitza, S; Jakupec, Michael; Uhl, Maria et al.
In: Cancer Letters, Vol. 226, No. 2, 2005, p. 115-121.

Publications: Contribution to journalArticlePeer Reviewed


Tuning of Redox Properties for the Design of Ruthenium Anticancer Drugs:  Part 2. Syntheses, Crystal Structures, and Electrochemistry of Potentially Antitumor [RuIII/IICl6-n(Azole)n]z (n = 3, 4, 6) Complexes. / Reisner, Erwin; Arion, Vladimir; Eichinger, Anna et al.
In: Inorganic Chemistry, Vol. 44, No. 19, 2005, p. 6704-6716.

Publications: Contribution to journalArticlePeer Reviewed


Two dimensional separation schemes for investigation of the interaction of an anticancer ruthenium(III) compound with plasma proteins. / Sulyok, Michael; Hann, Stephan; Hartinger, Christian et al.
In: Journal of Analytical Atomic Spectrometry, Vol. 20, No. 9, 2005, p. 856-863.

Publications: Contribution to journalArticlePeer Reviewed


1,1'-Bis(oxazolin-2-yl)ferrocenes: An investigation of their complexation behavior toward [Pd(?3-allyl)Cl]2. / Hartinger, Christian; Nazarov, Alexey; Arion, Vladimir et al.
In: European Journal of Inorganic Chemistry, No. 8, 2005, p. 1589-1600.

Publications: Contribution to journalArticlePeer Reviewed


2004


A comparative study of adduct formation between the anticancer ruthenium(III) compound HInd trans-[RuCl4(Ind)2] and serum proteins. / Piccioli, F; Sabatini, S; Messori, Luigi (Corresponding author) et al.
In: Journal of Inorganic Biochemistry, Vol. 98, No. 6, 2004, p. 1135-1142.

Publications: Contribution to journalArticlePeer Reviewed


Analysis of platinum adducts with DNA nucleotides and nucleosides by capillary electrophoresis coupled to ESI-MS: Indications of guanosine 5'-monophosphate O6-N7 chelation. / Warnke, Ulrich; Rappel, Christina; Meier, Heiko et al.
In: ChemBioChem: a european journal of chemical biology, Vol. 5, No. 11, 2004, p. 1543-1549.

Publications: Contribution to journalArticlePeer Reviewed


First data on structure-activity relations for the antitumor complexes [RuCl4(azole)2]. / Reisner, Erwin; Arion, Vladimir; Keppler, Bernhard et al.
In: Russian Chemical Journal, Vol. 48, No. 4, 2004, p. 137-139.

Publications: Contribution to journalArticlePeer Reviewed


Gallium in cancer treatment. / Jakupec, Michael; Keppler, Bernhard (Corresponding author).
In: Current Topics in Medicinal Chemistry, Vol. 4, No. 15, 2004, p. 1575-1583.

Publications: Contribution to journalReviewPeer Reviewed


Platinum metallodrug-protein binding studies by capillary electrophoresis-inductively coupled plasma-mass spectrometry: Characterization of interactions between Pt(II) complexes and human serum albumin. / Timerbaev, Andrei; Aleksenko, Svetlana S.; Polec-Pawlak, Katarzyna et al.
In: Electrophoresis, Vol. 25, No. 13, 2004, p. 1988-1995.

Publications: Contribution to journalArticlePeer Reviewed


Synthesis, crystal structure and cytotoxicity of new oxaliplatin analogues indicating that improvement of anticancer activity is still possible. / Galanski, Mathea Sophia; Yasemi, Afshin; Slaby, Susanna et al.
In: European Journal of Medicinal Chemistry, Vol. 39, No. 8, 2004, p. 707-714.

Publications: Contribution to journalArticlePeer Reviewed


Synthesis, crystal structure and pH dependent cytotoxicity of (SP-4-2)-bis(2-aminoethanolato-kappa2N,O)platinum(II) - A representative of novel pH sensitive anticancer platinum complexes. / Galanski, Mathea Sophia; Baumgartner, Christian; Meelich, Kristof et al.
In: Inorganica Chimica Acta, Vol. 357, No. 11, 2004, p. 3237-3244.

Publications: Contribution to journalArticlePeer Reviewed


Tuning of Redox Potentials for the Design of Ruthenium Anticancer Drugs − an Electrochemical Study of [trans-RuCl4L(DMSO)]- and [trans-RuCl4L2]- Complexes, where L = Imidazole, 1,2,4-Triazole, Indazole. / Reisner, Erwin; Arion, Vladimir; Guedes Da Silva, M F C et al.
In: Inorganic Chemistry, Vol. 43, No. 22, 2004, p. 7083-7093.

Publications: Contribution to journalArticlePeer Reviewed