Publications Institute of Inorganic Chemistry


2010


Novel cis- and trans-configured bis(oxime)platinum(II) complexes: Synthesis, characterization, and cytotoxic activity. / Scaffidi-Domianello, Yulia; Meelich, Kristof; Jakupec, Michael et al.
In: Inorganic Chemistry, Vol. 49, No. 12, 2010, p. 5669-5678.

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Organometallic indolo[3,2-c]quinolines versus indolo[3,2-d]benzazepines: synthesis, structural and spectroscopic characterization, and biological efficacy. / Filak, Lukas; Mühlgassner, Gerhard; Jakupec, Michael et al.
In: Journal of Biological Inorganic Chemistry, Vol. 15, No. 6, 2010, p. 903-918.

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Osmium(II)- versus ruthenium(II)-arene carbohydrate-based anticancer compounds: similarities and differences. / Nazarov, Alexey (Corresponding author); Hartinger, Christian (Corresponding author); Kandioller, Wolfgang et al.
In: Dalton Transactions, Vol. 39, No. 31, 2010, p. 7345-7352.

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Phosphonium and ammonium ionic liquids with aromatic anions: Synthesis, properties, and platinum extraction. / Stojanovic, Anja; Kogelnig, Daniel; Fischer, Lisa et al.
In: Australian Journal of Chemistry: an international journal for chemical science, Vol. 63, No. 3, 2010, p. 511-524.

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Relevance of peat-draining rivers for the riverine input of dissolved iron into the ocean. / Krachler, Regina (Corresponding author); Krachler, Rudolf; von der Kammer, Frank et al.
In: Science of the Total Environment, Vol. 408, No. 11, 2010, p. 2402-2408.

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Ruthenium versus platinum: Interactions of anticancer metallodrugs with duplex oligonucleotides characterised by electrospray ionisation mass spectrometry. / Groessl, Michael; Tsybin, Yury O.; Hartinger, Christian et al.
In: Journal of Biological Inorganic Chemistry, Vol. 15, No. 5, 2010, p. 677-688.

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Ruthenium(II)-arene complexes with functionalized pyridines: Synthesis, characterization and cytotoxic activity. / Grguric-Sipka, Sanja; Ivanovic, Ivanka; Rakic, Gordana M. et al.
In: European Journal of Medicinal Chemistry, Vol. 45, No. 3, 2010, p. 1051-1058.

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Structure-Activity Relationships of Highly Cytotoxic Copper(II) Complexes with Modified Indolo[3,2-c]quinoline Ligands. / Primik, Michael; Göschl, Simone; Jakupec, Michael et al.
In: Inorganic Chemistry, Vol. 49, No. 23, 2010, p. 11084-11095.

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Synthesis and crystal structure of N-phenyl-N?-(pyridin-2-ylmethyl)-S-methyl-thiouronium iodide. / Stojanovic, Anja; Morgenbesser, Cornelia; Galanski, Mathea Sophia et al.
In: Journal of Molecular Structure, Vol. 965, No. 1-3, 2010, p. 50-55.

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Synthesis and structures of novel 1-methylcytosinato-bridged (ethylenediamine)platinum(II) and platinum(III) dinuclear complexes. / Djinovic, Vesna; Galanski, Mathea Sophia; Arion, Vladimir et al.
In: Dalton Transactions, Vol. 39, No. 15, 2010, p. 3633-3643.

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Synthetic and Electrochemical Studies of [2Fe2S] Complexes Containing a 4-Amino-1,2-dithiolane-4-carboxylic Acid Moiety. / Apfel, Ulf-Peter; Kowol, Christian; Morera, Enrico et al.
In: European Journal of Inorganic Chemistry, Vol. 32, 2010, p. 5079-5086.

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Tetrachloroferrate containing ionic liquids: Magnetic- and aggregation behavior. / Kogelnig, Daniel (Corresponding author); Stojanovic, Anja; von der Kammer, Frank et al.
In: Inorganic Chemistry Communications, Vol. 13, No. 12, 2010, p. 1485-1488.

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The first example of MEEKC-ICP-MS coupling and its application for the analysis of anticancer platinum complexes. / Bytzek, Anna; Reithofer, Michael; Galanski, Mathea Sophia et al.
In: Electrophoresis, Vol. 31, No. 7, 2010, p. 1144-1150.

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The influence of electroporation on cytotoxicity of anticancer ruthenium(III) complex KP1339 in vitro and in vivo. / Hudej, Rosana; Turel, Iztok; Kanduser, Masa et al.
In: Anticancer Research: International journal of cancer research and treatment, Vol. 30, No. 6, 2010, p. 2055-2063.

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{(1R,2R,4R)-4-Methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): A Novel Enantiomerically Pure Oxaliplatin Derivative Showing Improved Anticancer Activity in Vivo. / Abramkin, Sergey; Jungwirth, Ute; Valiahdi, Seied Mojtaba et al.
In: Journal of Medicinal Chemistry, Vol. 53, No. 20, 2010, p. 7356-7364.

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2009


Radiosynthesis of the adenosine a3 receptor ligand 5-(2-[18F]fluoroethyl)2,4,-diethyl-3-(ethylsulfanylcarbonyl)-6-phenylpyridine-5-carboxylate([18F]FE@SUPPY). / Wadsak, Wolfgang (Corresponding author); Mien, Leonhard-Key; Shanab, Karem et al.
In: Radiochimica Acta: international journal for chemical aspects of nuclear science and technology, Vol. 96, No. 2, 25.09.2009, p. 119-124.

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A one step/one pot synthesis of N,N-bis(phosphonomethyl)amino acids and their effects on adipogenic and osteogenic differentiation of human mesenchymal stem cells. / Hubinger-Kasser, Johanna; Nazarov, Alexey; Hartinger, Christian et al.
In: Bioorganic & Medicinal Chemistry, Vol. 17, No. 9, 2009, p. 3388-3393.

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Biodistribution of anti-diabetic Zn(II) complexes in human serum and in vitro protein-binding studies by means of CZE-ICP-MS. / Bytzek, Anna; Enyedy, Eva Anna; Kiss, Tamas et al.
In: Electrophoresis, Vol. 30, 2009, p. 4075-4082.

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Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cells. / Egger, Alexander; Rappel, Christina; Jakupec, Michael et al.
In: Journal of Analytical Atomic Spectrometry, Vol. 24, No. 1, 2009, p. 51-61.

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DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media. / Novakova, Olga; Nazarov, Alexey; Hartinger, Christian et al.
In: Biochemical Pharmacology, Vol. 77, No. 3, 2009, p. 364-374.

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From pyrone to thiopyrone ligands-rendering maltol-derived ruthenium(II)-arene complexes that are anticancer active in vitro. / Kandioller, Wolfgang; Hartinger, Christian; Nazarov, Alexey et al.
In: Organometallics, Vol. 28, No. 15, 2009, p. 4249-4251.

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Impact of metal coordination on cytotoxicity of 3-aminopyridine-2- carboxaldehyde thiosemicarbazone (Triapine) and novel insights into terminal dimethylation. / Kowol, Christian; Trondl, Robert; Heffeter, Petra et al.
In: Journal of Medicinal Chemistry, Vol. 52, No. 16, 2009, p. 5032-5043.

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Influence of Structural Variation on the Anticancer Activity of RAPTA-Type Complexes: ptn versus pta. / Renfrew, Anna K.; Phillips, Andrew; Egger, Alexander et al.
In: Organometallics, Vol. 28, No. 4, 2009, p. 1165-1172.

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Influence of the Arene Ligand, the Number and Type of Metal Centers, and the Leaving Group on the in Vitro Antitumor Activity of Polynuclear Organometallic Compounds. / Mendoza Parra Ferri, Maria Grazia; Hartinger, Christian; Nazarov, Alexey A. et al.
In: Organometallics, Vol. 28, No. 21, 2009, p. 6260-6265.

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Inhibitory effects of the ruthenium complex KP1019 in models of mammary cancer cell migration and invasion. / Bergamo, Alberta C.; Masi, Alessia; Jakupec, Michael et al.
In: Metal-Based Drugs : MBD, Vol. 2009, 2009.

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Investigation of amino acid containing [FeFe] hydrogenase models concerning pendant base effects. / Apfel, Ulf-Peter; Kowol, Christian; Halpin, Yvonne et al.
In: Journal of Inorganic Biochemistry, Vol. 103, No. 9, 2009, p. 1236-1244.

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Maltol-derived ruthenium-cymene complexes with tumor inhibiting properties: the impact of ligand-metal bond stability on anticancer activity in vitro. / Kandioller, Wolfgang; Hartinger, Christian (Corresponding author); Nazarov, Alexey (Corresponding author) et al.
In: Chemistry: A European Journal, Vol. 15, No. 45, 2009, p. 12283-12291.

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New insights into the chemistry of the antineoplastic lanthanum complex tris(1,10-phenanthroline)tris(thiocyanato-?N)lanthanum(III) (KP772) and its interaction with biomolecules. / Biba, Florian; Größl, Michael (Corresponding author); Egger, Alexander et al.
In: European Journal of Inorganic Chemistry, Vol. 28, 2009, p. 4282-4287.

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[Os(IV)Cl5(Hazole)](-) complexes: synthesis, structure, spectroscopic properties and antiproliferative activity. / Arion, Vladimir (Corresponding author); Büchel, Gabriel; Stepanenko, Iryna et al.
In: Inorganic Chemistry, Vol. 48, No. 22, 2009, p. 10737-10747.

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Patient Bologna: Zustand ernst, aber nicht hoffnungslos! / Spiel, Christiane; Keppler, Bernhard.
In: VSH-Bulletin, Vol. 35, No. 3, 2009, p. 64-65.

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Pharmacokinetics of a novel anticancer ruthenium complex (KP1019, FFC14A) in a phase i dose-escalation study. / Lentz, Frederike; Drescher, Anne; Lindauer, Andreas et al.
In: ANTI-CANCER DRUGS, Vol. 20, No. 2, 2009, p. 97-103.

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Ribonucleotide reductase as one important target of [Tris(1,10- phenanthroline)lanthanum(III)] trithiocyanate (KP772). / Heffeter, Petra; Popovic-Bijelic, Ana; Saiko, Philipp et al.
In: Current Cancer Drug Targets, Vol. 9, No. 5, 2009, p. 595-607.

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Synthesis and biological studies of some gold(I) complexes containing functionalised alkynes. / Schuh, Esther; Valiahdi, Seied Mojtaba; Jakupec, Michael et al.
In: Dalton Transactions, Vol. 2009, 2009, p. 10841-10845.

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Synthesis and structures of palladium(II) and platinum(II) complexes containing heterocyclic thiolate ligands formed by cycloaddition reactions of coordinated azides. / Fleischer, Angela; Roller, Alexander; Arion, Vladimir et al.
In: Canadian Journal of Chemistry, Vol. 87, No. 1, 2009, p. 146-150.

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Synthesis, X-ray diffraction structure, spectroscopic properties and antiproliferative activity of a novel ruthenium complex with constitutional similarity to cisplatin. / Grguric-Sipka, Sanja; Stepanenko, Iryna; Lazic, Jelena M. et al.
In: Dalton Transactions, Vol. 17, 2009, p. 3334-3339.

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The gallium complex KP46 exerts strong activity against primary explanted melanoma cells and induces apoptosis in melanoma cell lines. / Valiahdi, Seied Mojtaba; Heffeter, Petra; Jakupec, Michael et al.
In: MELANOMA RESEARCH, Vol. 19, No. 5, 2009, p. 283-293.

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Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity. / Hartinger, Christian; Mendoza Parra, Marco-Antonio; Größl, Michael et al.
In: Journal of Medicinal Chemistry, Vol. 52, No. 4, 2009, p. 916-925.

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Tuning the anticancer activity of maltol-derived ruthenium complexes by derivatization of the 3-hydroxy-4-pyrone moiety. / Kandioller, Wolfgang; Hartinger, Christian; Nazarov, Alexey et al.
In: Journal of Organometallic Chemistry, Vol. 694, No. 6, 2009, p. 922-929.

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5-Hydroxy-2-methyl-4H-pyran-4-one. / Shaheen, Muhammad Ashraf; Hartinger, Christian; Tahir, M. Nawaz et al.
In: Acta Crystallographica. Section E: Structure Reports Online, Vol. 65, No. 2, 2009.

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2008


Preparation and first evaluation of [F-18]FE@SUPPY: a new PET tracer for the adenosine A(3) receptor. / Wadsak, Wolfgang; Mien, Leonhard-Key; Shanab, Karem et al.
In: Nuclear Medicine and Biology, Vol. 35, No. 1, 01.2008, p. 61-66.

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An electrochemical study of antineoplastic gallium, iron and ruthenium complexes with redox non-innocent alpha-N-heterocyclic chalcogensemicarbazones. / Kowol, Christian; Reisner, Erwin (Corresponding author); Chiorescu, Ion et al.
In: Inorganic Chemistry, Vol. 47, No. 23, 2008, p. 11032-11047.

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Analysis of quaternary ammonium and phosphonium ionic liquids by reversed-phase high-performance liquid chromatography with charged aerosol detection and unified calibration. / Stojanovic, Anja; Lämmerhofer, Michael (Corresponding author); Kogelnig, Daniel (Corresponding author) et al.
In: Journal of Chromatography A, Vol. 1209, No. 1-2, 2008, p. 179-187.

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Antitumour metal compounds: more than theme and variations. / Jakupec, Michael (Corresponding author); Galanski, Mathea Sophia; Arion, Vladimir et al.
In: Dalton Transactions, Vol. 2008, No. 2, 2008, p. 183-194.

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Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: a Novel Approach for the Analysis of Anticancer Metallodrugs in Human Serum and Plasma. / Größl, Michael; Hartinger, Christian (Corresponding author); Polec-Pawlak, Katarzyna et al.
In: Electrophoresis, Vol. 29, No. 10, 2008, p. 2224-2232.

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Capillary electrophoretic assay for the stability of tris(8-quinolinolato)gallium(III) in tablet formulations. / Keppler, Bernhard; Timerbaev, Andrei (Corresponding author); Stolyarova, Natalya et al.
In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 48, 2008, p. 218-222.

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Carbohydrate–Metal Complexes and their Potential as Anticancer Agents. / Hartinger, Christian; Nazarov, Alexey; Dyson, Paul J. et al.
In: Current Medicinal Chemistry, Vol. 15, No. 25, 2008, p. 2574-2591.

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Computational electrochemistry of ruthenium anticancer agents. Unprecedented benchmarking of implicit solvation methods. / Deubel, Dirk (Corresponding author); Chiorescu, Ion; Arion, Vladimir et al.
In: Journal of Chemical Theory and Computation, Vol. 4, 2008, p. 499-506.

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CZE-ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP. / Größl, Michael; Hartinger, Christian; Dyson, Paul J. et al.
In: Journal of Inorganic Biochemistry, Vol. 102, 2008, p. 1060-1065.

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