Publications Institute of Inorganic Chemistry


2009


A one step/one pot synthesis of N,N-bis(phosphonomethyl)amino acids and their effects on adipogenic and osteogenic differentiation of human mesenchymal stem cells. / Hubinger-Kasser, Johanna; Nazarov, Alexey; Hartinger, Christian et al.
In: Bioorganic & Medicinal Chemistry, Vol. 17, No. 9, 2009, p. 3388-3393.

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Biodistribution of anti-diabetic Zn(II) complexes in human serum and in vitro protein-binding studies by means of CZE-ICP-MS. / Bytzek, Anna; Enyedy, Eva Anna; Kiss, Tamas et al.
In: Electrophoresis, Vol. 30, 2009, p. 4075-4082.

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Development of an experimental protocol for uptake studies of metal compounds in adherent tumor cells. / Egger, Alexander; Rappel, Christina; Jakupec, Michael et al.
In: Journal of Analytical Atomic Spectrometry, Vol. 24, No. 1, 2009, p. 51-61.

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DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media. / Novakova, Olga; Nazarov, Alexey; Hartinger, Christian et al.
In: Biochemical Pharmacology, Vol. 77, No. 3, 2009, p. 364-374.

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From pyrone to thiopyrone ligands-rendering maltol-derived ruthenium(II)-arene complexes that are anticancer active in vitro. / Kandioller, Wolfgang; Hartinger, Christian; Nazarov, Alexey et al.
In: Organometallics, Vol. 28, No. 15, 2009, p. 4249-4251.

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Impact of metal coordination on cytotoxicity of 3-aminopyridine-2- carboxaldehyde thiosemicarbazone (Triapine) and novel insights into terminal dimethylation. / Kowol, Christian; Trondl, Robert; Heffeter, Petra et al.
In: Journal of Medicinal Chemistry, Vol. 52, No. 16, 2009, p. 5032-5043.

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Influence of Structural Variation on the Anticancer Activity of RAPTA-Type Complexes: ptn versus pta. / Renfrew, Anna K.; Phillips, Andrew; Egger, Alexander et al.
In: Organometallics, Vol. 28, No. 4, 2009, p. 1165-1172.

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Influence of the Arene Ligand, the Number and Type of Metal Centers, and the Leaving Group on the in Vitro Antitumor Activity of Polynuclear Organometallic Compounds. / Mendoza Parra Ferri, Maria Grazia; Hartinger, Christian; Nazarov, Alexey A. et al.
In: Organometallics, Vol. 28, No. 21, 2009, p. 6260-6265.

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Inhibitory effects of the ruthenium complex KP1019 in models of mammary cancer cell migration and invasion. / Bergamo, Alberta C.; Masi, Alessia; Jakupec, Michael et al.
In: Metal-Based Drugs : MBD, Vol. 2009, 2009.

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Investigation of amino acid containing [FeFe] hydrogenase models concerning pendant base effects. / Apfel, Ulf-Peter; Kowol, Christian; Halpin, Yvonne et al.
In: Journal of Inorganic Biochemistry, Vol. 103, No. 9, 2009, p. 1236-1244.

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Maltol-derived ruthenium-cymene complexes with tumor inhibiting properties: the impact of ligand-metal bond stability on anticancer activity in vitro. / Kandioller, Wolfgang; Hartinger, Christian (Corresponding author); Nazarov, Alexey (Corresponding author) et al.
In: Chemistry: A European Journal, Vol. 15, No. 45, 2009, p. 12283-12291.

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New insights into the chemistry of the antineoplastic lanthanum complex tris(1,10-phenanthroline)tris(thiocyanato-?N)lanthanum(III) (KP772) and its interaction with biomolecules. / Biba, Florian; Größl, Michael (Corresponding author); Egger, Alexander et al.
In: European Journal of Inorganic Chemistry, Vol. 28, 2009, p. 4282-4287.

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[Os(IV)Cl5(Hazole)](-) complexes: synthesis, structure, spectroscopic properties and antiproliferative activity. / Arion, Vladimir (Corresponding author); Büchel, Gabriel; Stepanenko, Iryna et al.
In: Inorganic Chemistry, Vol. 48, No. 22, 2009, p. 10737-10747.

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Patient Bologna: Zustand ernst, aber nicht hoffnungslos! / Spiel, Christiane; Keppler, Bernhard.
In: VSH-Bulletin, Vol. 35, No. 3, 2009, p. 64-65.

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Pharmacokinetics of a novel anticancer ruthenium complex (KP1019, FFC14A) in a phase i dose-escalation study. / Lentz, Frederike; Drescher, Anne; Lindauer, Andreas et al.
In: ANTI-CANCER DRUGS, Vol. 20, No. 2, 2009, p. 97-103.

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Ribonucleotide reductase as one important target of [Tris(1,10- phenanthroline)lanthanum(III)] trithiocyanate (KP772). / Heffeter, Petra; Popovic-Bijelic, Ana; Saiko, Philipp et al.
In: Current Cancer Drug Targets, Vol. 9, No. 5, 2009, p. 595-607.

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Synthesis and biological studies of some gold(I) complexes containing functionalised alkynes. / Schuh, Esther; Valiahdi, Seied Mojtaba; Jakupec, Michael et al.
In: Dalton Transactions, Vol. 2009, 2009, p. 10841-10845.

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Synthesis and structures of palladium(II) and platinum(II) complexes containing heterocyclic thiolate ligands formed by cycloaddition reactions of coordinated azides. / Fleischer, Angela; Roller, Alexander; Arion, Vladimir et al.
In: Canadian Journal of Chemistry, Vol. 87, No. 1, 2009, p. 146-150.

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Synthesis, X-ray diffraction structure, spectroscopic properties and antiproliferative activity of a novel ruthenium complex with constitutional similarity to cisplatin. / Grguric-Sipka, Sanja; Stepanenko, Iryna; Lazic, Jelena M. et al.
In: Dalton Transactions, Vol. 17, 2009, p. 3334-3339.

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The gallium complex KP46 exerts strong activity against primary explanted melanoma cells and induces apoptosis in melanoma cell lines. / Valiahdi, Seied Mojtaba; Heffeter, Petra; Jakupec, Michael et al.
In: MELANOMA RESEARCH, Vol. 19, No. 5, 2009, p. 283-293.

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Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity. / Hartinger, Christian; Mendoza Parra, Marco-Antonio; Größl, Michael et al.
In: Journal of Medicinal Chemistry, Vol. 52, No. 4, 2009, p. 916-925.

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Tuning the anticancer activity of maltol-derived ruthenium complexes by derivatization of the 3-hydroxy-4-pyrone moiety. / Kandioller, Wolfgang; Hartinger, Christian; Nazarov, Alexey et al.
In: Journal of Organometallic Chemistry, Vol. 694, No. 6, 2009, p. 922-929.

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5-Hydroxy-2-methyl-4H-pyran-4-one. / Shaheen, Muhammad Ashraf; Hartinger, Christian; Tahir, M. Nawaz et al.
In: Acta Crystallographica. Section E: Structure Reports Online, Vol. 65, No. 2, 2009.

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2008


Preparation and first evaluation of [F-18]FE@SUPPY: a new PET tracer for the adenosine A(3) receptor. / Wadsak, Wolfgang; Mien, Leonhard-Key; Shanab, Karem et al.
In: Nuclear Medicine and Biology, Vol. 35, No. 1, 01.2008, p. 61-66.

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An electrochemical study of antineoplastic gallium, iron and ruthenium complexes with redox non-innocent alpha-N-heterocyclic chalcogensemicarbazones. / Kowol, Christian; Reisner, Erwin (Corresponding author); Chiorescu, Ion et al.
In: Inorganic Chemistry, Vol. 47, No. 23, 2008, p. 11032-11047.

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Analysis of quaternary ammonium and phosphonium ionic liquids by reversed-phase high-performance liquid chromatography with charged aerosol detection and unified calibration. / Stojanovic, Anja; Lämmerhofer, Michael (Corresponding author); Kogelnig, Daniel (Corresponding author) et al.
In: Journal of Chromatography A, Vol. 1209, No. 1-2, 2008, p. 179-187.

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Antitumour metal compounds: more than theme and variations. / Jakupec, Michael (Corresponding author); Galanski, Mathea Sophia; Arion, Vladimir et al.
In: Dalton Transactions, Vol. 2008, No. 2, 2008, p. 183-194.

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Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: a Novel Approach for the Analysis of Anticancer Metallodrugs in Human Serum and Plasma. / Größl, Michael; Hartinger, Christian (Corresponding author); Polec-Pawlak, Katarzyna et al.
In: Electrophoresis, Vol. 29, No. 10, 2008, p. 2224-2232.

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Capillary electrophoretic assay for the stability of tris(8-quinolinolato)gallium(III) in tablet formulations. / Keppler, Bernhard; Timerbaev, Andrei (Corresponding author); Stolyarova, Natalya et al.
In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 48, 2008, p. 218-222.

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Carbohydrate–Metal Complexes and their Potential as Anticancer Agents. / Hartinger, Christian; Nazarov, Alexey; Dyson, Paul J. et al.
In: Current Medicinal Chemistry, Vol. 15, No. 25, 2008, p. 2574-2591.

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Computational electrochemistry of ruthenium anticancer agents. Unprecedented benchmarking of implicit solvation methods. / Deubel, Dirk (Corresponding author); Chiorescu, Ion; Arion, Vladimir et al.
In: Journal of Chemical Theory and Computation, Vol. 4, 2008, p. 499-506.

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CZE-ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP. / Größl, Michael; Hartinger, Christian; Dyson, Paul J. et al.
In: Journal of Inorganic Biochemistry, Vol. 102, 2008, p. 1060-1065.

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Electron-transfer activated metal-based anticancer drugs. / Reisner, Erwin (Corresponding author); Arion, Vladimir; Keppler, Bernhard et al.
In: Inorganica Chimica Acta, Vol. 361, 2008, p. 1569-1583.

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Elucidation of the Interactions of an Anticancer Ruthenium Complex in Clinical Trials with Biomolecules Utilizing Capillary Electrophoresis Hyphenated to Inductively Coupled Plasma-Mass Spectrometry. / Größl, Michael; Hartinger, Christian (Corresponding author); Polec-Pawlak, Katarzyna et al.
In: Chemistry & Biodiversity, Vol. 5, No. 8, 2008, p. 1609-1614.

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Gold(III) compounds as anticancer agents: Relevance of gold-protein interactions for their mechanism of action. / Casini, Angela; Hartinger, Christian; Gabbiani, Chiara et al.
In: Journal of Inorganic Biochemistry, Vol. 102, 2008, p. 564-575.

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Greener synthesis of new ammonium ionic liquids and their potential as extracting agents. / Kogelnig, Daniel; Stojanovic, Anja; Galanski, Mathea Sophia et al.
In: Tetrahedron Letters, No. 49, 2008, p. 2782-2785.

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High Resolution Mass Spectrometry for Studying the Interactions of Cisplatin with Oligonucleotides. / Egger, Alexander; Hartinger, Christian (Corresponding author); Ben Hamidane, Hisham et al.
In: Inorganic Chemistry, Vol. 47, No. 22, 2008, p. 10626-10633.

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Hydrolysis and cytotoxic properties of osmium(II)/(III)-DMSO-azole complexes. / Egger, Alexander; Cebrian, Berta; Stepanenko, Iryna et al.
In: Chemistry & Biodiversity, Vol. 5, No. 8, 2008, p. 1588-1593.

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Hydrolysis study of the bifunctional antitumour compound RAPTA-C, [Ru(η6-p-cymene)Cl2(pta)]. / Scolaro, C; Hartinger, Christian (Corresponding author); Allardyce, Claire et al.
In: Journal of Inorganic Biochemistry, Vol. 102, 2008, p. 1743-1748.

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In vitro anticancer activity and biologically-relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands. / Berger, Isabella; Nazarov, Alexey (Corresponding author); Hartinger, Christian (Corresponding author) et al.
In: Chemistry: A European Journal, Vol. 14, No. 29, 2008, p. 9046-9057.

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Influence of the spacer length on the in vitro anticancer activity of dinuclear ruthenium-arene compounds. / Mendoza Parra Ferri, Maria Grazia; Hartinger, Christian (Corresponding author); Eichinger, Rene et al.
In: Organometallics, Vol. 27, No. 11, 2008, p. 2405-2407.

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KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients. / Hartinger, Christian (Corresponding author); Jakupec, Michael; Zorbas-Seifried, Stefanie et al.
In: Chemistry & Biodiversity, Vol. 5, No. 10, 2008, p. 2140-2155.

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Methyl-substituted trans-1,2-cyclohexanediamines as new ligands for oxaliplatin-type complexes. / Habala, Ladislav; Dworak, Claudia; Nazarov, Alexey et al.
In: Tetrahedron, Vol. 64, No. 1, 2008, p. 137-146.

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Modifying the Structure of Dinuclear Ruthenium Complexes with Antitumor Activity. / Mendoza Parra Ferri, Maria Grazia; Hartinger, Christian (Corresponding author); Nazarov, Alexey (Corresponding author) et al.
In: Applied Organometallic Chemistry, Vol. 22, 2008, p. 326-332.

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Nanoparticles for diagnosis of blood vessel diseases. / Kundu, Amitava; Keppler, Bernhard.
In: Nachrichten aus der Chemie, Vol. 55, No. 9, 2008, p. 842-846.

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Novel and mild route to phthalocyanines and 3-iminoisoindolin1-ones via N,N-diethylhydroxylamine-promoted conversion of phthalonitriles and a dramatic solvent-dependence of the reaction. / Luzyanin, Konstantin V.; Kukushkin, Vadim Yu; Kopylovich, Maximilian N. et al.
In: Advanced Synthesis & Catalysis, Vol. 350, No. 1, 2008, p. 135-142.

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Novel bis(carboxylato)dichlorido(ethane-1,2-diamine)platinum(IV) complexes with exceptionally high cytotoxicity. / Reithofer, Michael (Corresponding author); Schwarzinger, Anne; Valiahdi, Seied Mojtaba et al.
In: Journal of Inorganic Biochemistry, Vol. 102, 2008, p. 2072-2077.

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Novel endothall containing platinum(IV) complexes - synthesis, characterization, and cytotoxic activity. / Reithofer, Michael; Valiahdi, Seied Mojtaba; Galanski, Mathea Sophia (Corresponding author) et al.
In: Chemistry & Biodiversity, Vol. 5, 2008, p. 2160-2170.

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