2024

Straightforward Synthesis of DFO* - An Octadentate Chelator for Zirconium-89
Guarrochena, X., Kronberger, J., Tieber, M., Ciesielski, P., Mindt, T. L. & Feiner, I. V. J.
ChemMedChem (2024) 19, 3, e202300495

2023­

Synthesis and Preclinical Evaluation of Radiolabeled [103Ru]BOLD-100
Happl, B., Brandt, M., Balber, T., Benčurová, K., Talip, Z., Voegele, A., Heffeter, P., Kandioller, W., Van der Meulen, N. P., Mitterhauser, M., Hacker, M., Keppler, B. K. & Mindt, T. L.
Pharmaceutics (2023) 15, 11, 2626

Automated solid-phase synthesis of metabolically stabilized triazolo-peptidomimetics
Guarrochena, X., Kaudela, B. & Mindt, T. L.
Journal of Peptide Science (2023) 29, 9, e3488

Effects of bilateral sequential theta-burst stimulation on 5-HT1A receptors in the dorsolateral prefrontal cortex in treatment-resistant depression: a proof-of-concept trial
Murgaš, M., Unterholzner, J., Stöhrmann, P., Philippe, C., Godbersen, G. M., Nics, L., Reed, M. B., Vraka, C., Vanicek, T., Wadsak, W., Kranz, G. S., Hahn, A., Mitterhauser, M., Hacker, M., Kasper, S. & Lanzenberger,
Translational Psychiatry (2023) 13, 1, 33

Fluorinated Analogues to the Pentuloses of the Pentose Phosphate Pathway
Scheibelberger, L., Stankovic, T., Liepert, K., Kienzle, A., Patronas, E. M., Balber, T., Mitterhauser, M., Haschemi, A. & Pallitsch, K.
European Journal of Organic Chemistry (2023) 26, 31, e202300339

Task-evoked metabolic demands of the posteromedial default mode network are shaped by dorsal attention and frontoparietal control networks
Godbersen, G. M., Klug, S., Wadsak, W., Pichler, V., Raitanen, J., Rieckmann, A., Stiernman, L., Cocchi, L., Breakspear, M., Hacker, M., Lanzenberger, R. & Hahn, A.
eLife (2023) 12, e84683

Towards Ruthenium(II)-Rhenium(I) Binuclear Complexes as Photosensitizers for Photodynamic Therapy
Wang, Y., Felder, P. S., Mesdom, P., Blacque, O., Mindt, T. L., Cariou, K. & Gasser, G., 2023
ChemBioChem (2023) e202300467

Comparison of Radiation Response between 2D and 3D Cell Culture Models of Different Human Cancer Cell Lines
Raitanen, J., Barta, B., Hacker, M., Georg, D., Balber, T. & Mitterhauser, M.
Cells (2023) 12, 3, 360

Consecutive Prostate-Specific Membrane Antigen (PSMA) and Antigen Receptor (AR) PET Imaging Shows Positive Correlation with AR and PSMA Protein Expression in Primary Hormone-Naïve Prostate Cancer
al Jalali, V., Wasinger, G., Rasul, S., Grubmüller, B., Wulkersdorfer, B., Balber, T., Mitterhauser, M., Simon, J., Hacker, M., Shariat, S., Egger, G. & Zeitlinger, M.
Journal of Nuclear Medicine (2023) 64, 6, 863-868

Quality Assurance Investigations and Impurity Characterization during Upscaling of [177Lu]Lu-PSMAI&T
Schmitl, S., Raitanen, J., Witoszynskyj, S., Patronas, E. M., Nics, L., Ozenil, M., Weissenböck, V., Mindt, T. L., Hacker, M., Wadsak, W., Brandt, M. R. & Mitterhauser, M.
Molecules (2023) 28, 23, 7696

Radiobiological Assessment of Targeted Radionuclide Therapy with [177Lu]Lu-PSMA-I&T in 2D vs. 3D Cell Culture Models
Raitanen, J., Barta, B., Fuchs, H., Hacker, M., Balber, T., Georg, D. & Mitterhauser, M.
International Journal of Molecular Sciences (2023) 24, 23, 17015

Synthesis of 4-Deoxy-4-Fluoro-D-Sedoheptulose: A Promising New Sugar to Apply the Principle of Metabolic Trapping
Scheibelberger, L., Stankovic, T., Pühringer, M., Kählig, H., Balber, T., Patronas, E. M., Rampler, E., Mitterhauser, M., Haschemi, A. & Pallitsch, K.
Chemistry - A European Journal (2023) 29, 62, e202302277

Influence of Ba concentration on Ra and 210Pb extraction from aqueous samples using EMPORE® radium RAD disks
Wallner, G.
Journal of Radioanalytical and Nuclear Chemistry (2023)

2022

Sympathetic nerve innervation and metabolism in ischemic myocardium in response to remote ischemic perconditioning
Kiss, A., Wu, P., Schlederer, M., Pilz, P. M., Szabo, P. L., Li, J., Weber, L., Vraka, C., Pichler, V., Mitterhauser, M., Zhang, X., Zins, K., Abraham, D., Li, S., Podesser, B. K., Hacker, M. & Li, X.
Basic research in cardiology (2022) 117, 1, 42

First-in-Humans Brain PET Imaging of the GluN2B-Containing N-methyl-D-aspartate Receptor with (R)-C-11-Me-NB1
Rischka, L., Vraka, C., Pichler, V., Rasul, S., Nics, L., Gryglewski, G., Handschuh, P., Murgas, M., Godbersen, G. M., Silberbauer, L. R., Unterholzner, J., Wotawa, C., Haider, A., Ahmed, H., Schibli, R., Mindt, T., Mitterhauser, M., Wadsak, W., Hahn, A., Lanzenberger, R., Hacker, M. & Ametamey, S. M.
Journal of Nuclear Medicine (2022) 63, 6, 936-941

Autoradiography on deparaffinized tissue sections – A feasibility study with 68Ga-labeled PET-tracers
Klebermass, E. M., Dengler, A., Weissenböck, V., Ricken, G., Wadsak, W., Viernstein, H., Hacker, M., Mitterhauser, M. & Philippe, C.
Applied Radiation and Isotopes (2022) 189, 110425

CAM-Xenograft Model Provides Preclinical Evidence for the Applicability of [68Ga]Ga-Pentixafor in CRC Imaging
Bencurova, K., Friske, J., Anderla, M., Mayrhofer, M., Wanek, T., Nics, L., Egger, G., Helbich, T. H., Hacker, M., Haug, A., Mitterhauser, M. & Balber, T.
Cancers (2022) 14, 22, 5549

Unexpected transformation of n.c.a. [¹¹¹In]InCl₃ in stock solutions into an unreactive [¹¹¹In]In-species
Giammei, C., Jouini, N., Brandt, M. R., Frey, S., Mindt, T. L. & Cardinale, J.
Applied Radiation and Isotopes (2022)180, 110037

Evaluation of a Radiolabeled Macrocyclic Peptide as Potential PET Imaging Probe for PD-L1
Jouini, N., Cardinale, J. & Mindt, T. L.
ChemMedChem (2022) 17, 12, 202200091

Experimental Nuclear Medicine Meets Tumor Biology
Balber, T., Tran, L., Bencurova, K., Raitanen, J., Egger, G. & Mitterhauser, M.
Pharmaceuticals (2022) 15, 2, 227

Simultaneous radiomethylation of [11C]harmine and [11C]DASB and kinetic modeling approach for serotonergic brain imaging in the same individual
Vraka, C., Murgaš, M., Rischka, L., Geist, B. K., Lanzenberger, R., Gryglewski, G., Zenz, T., Wadsak, W., Mitterhauser, M., Hacker, M., Philippe, C. & Pichler, V.
Scientific Reports (2022) 12, 1, 3283

Retrospective determination of U and Pu isotopes and atom ratios in lung samples from Vienna, Austria
Wallner, G., Zima, P., Moser, M., Uguz, H., Bartmann, M. G., Steier, P. & Hain, K.
Journal of Environmental Radioactivity (2022) 251-252, 7,106965

Retrospective determination of fallout radionuclides and 236U/238U, 233U/236U and 240Pu/239Pu atom ratios on air filters from Vienna and Salzburg, Austria
Wallner, G., Uguz, H., Kern, M., Jirsa, F. & Hain, K.
Journal of Environmental Radioactivity (2022) 255, 107030

Task-positive networks differentially shape glucose metabolism of the posteromedial default mode network as revealed by [18F]FDG-PET/MR imaging
Godbersen, G., Klug, S., Wadsak, W., Pichler, V., Raitanen, J., Rieckmann, A., Stiernman, L., Cocchi, L., Breakspear, M., Hacker, M., Lanzenberger, R. & Hahn, A.
Neuroscience Applied. 1, Suppl.2 (2022) 100684

2021

The Race for Hydroxamate-Based Zirconium-89 Chelators
Feiner, I. V. J., Brandt, M., Cowell, J., Demuth, T., Vugts, D., Gasser, G. & Mindt, T. L.
Cancers (2021) 13, 17, 4466

Development and in vitro evaluation of new bifunctional Zr-89-chelators based on the 6-amino-1,4-diazepane scaffold for immuno-PET applications
Klasen, B., Lemcke, D., Mindt, T. L., Gasser, G. & Roesch, F.
Nuclear Medicine and Biology (2021), 102, 12-23

Improved Tumor-Targeting with Peptidomimetic Analogs of Minigastrin Lu-177-PP-F11N
Grob, N. M., Schibli, R., Behe, M. & Mindt, T. L.
Cancers (2021) 13, 11, 2629

1,5-Disubstituted 1,2,3-Triazoles as Amide Bond Isosteres Yield Novel Tumor-Targeting Minigastrin Analogs
Grob, N. M., Schibli, R., Behe, M., Valverde, I. E. & Mindt, T. L.
ACS Medicinal Chemistry Letters (2021) 12, 4, 585-592

Overall Retention of Methyl Stereochemistry during B-12-Dependent Radical SAM Methyl Transfer in Fosfomycin Biosynthesis
McLaughlin, M., Pallitsch, K., Wallner, G., van der Donk, W. A. & Hammerschmidt, F.
Biochemistry (2021) 60, 20, 1587-1596

Determination of Characteristic vs Anomalous Cs-135/Cs-137 Isotopic Ratios in Radioactively Contaminated Environmental Samples
Zok, D., Blenke, T., Reinhard, S., Sprott, S., Kegler, F., Syrbe, L., Querfeld, R., Takagai, Y., Drozdov, V., Chyzhevskyi, I., Kirieiev, S., Schmidt, B., Adlassnig, W., Wallner, G., Dubchak, S. & Steinhauser, G.
Environmental Science & Technology (2021) 55, 8, 4984-4991

2020

1,4-Disubstituted 1,2,3-Triazoles as Amide Bond Surrogates for the Stabilisation of Linear Peptides with Biological Activity
Recnik, L-M., Kandioller, W. & Mindt, T. L.
Molecules (2020) 25, 16, 3576

Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity
Vrettos, E., Valverde, I. E., Mascarin, A., Pallier, P. N., Cerofolini, L., Fragai, M., Parigi, G., Hirmiz, B., Bekas, N., Grob, N. M., Shaye, H., Del Borgo, M., Aguilar, M., Magnani, F., Syed, N., Crook, T., Waqif, E., Ghazaly, E., Cherezov, V., Widdop, R. E., Luchinat, C., Michael-Titus, A. T., Mindt, T. L., Tzakos, A. G. & Stylos, E. K.
Chemistry: A European Journal (2020) 26, 47, 10690-10694

Radiolabelling of the octadentate chelators DFO* and oxoDFO* with zirconium-89 and gallium-68
Brandt, M., Cowell, J., Aulsebrook, M. L., Gasser, G. & Mindt, T. L.
Journal of Biological Inorganic Chemistry (2020) 25, 789–796

Sorbitol as a Polar Pharmacological Modifier to Enhance the Hydrophilicity of 99mTc-Tricarbonyl-Based Radiopharmaceuticals
Giammei, C., Balber, T., Benčurová, K., Cardinale, J., Berroterán-Infante, N., Brandt, M., Jouini, N., Hacker, M., Mitterhauser, M. & Mindt, T. L.
Molecules (2020) 25, 11, 2680

Design of Radiolabeled Analogs of Minigastrin by Multiple Amide-to-Triazole Substitutions
Grob, N. M., Schmid, S., Schibli, R., Behe, M. & Mindt, T. L.
Journal of Medicinal Chemistry (2020) 63, 9, 4496-4505

Triazolo-Peptidomimetics: Novel Radiolabeled Minigastrin Analogs for Improved Tumor Targeting
Grob, N. M., Haussinger, D., Deupi, X., Schibli, R., Behe, M. & Mindt, T. L.
Medicinal Chemistry (2020) 63, 9, 4484-4495

2019

Manganese in PET imaging: Opportunities and challenges
Brandt, M., Cardinale, J., Rausch, I. & Mindt, T. L.
Journal of Labelled Compounds and Radiopharmaceuticals (2019) 62, 8, 541-551

Mini-review: Targeted radiopharmaceuticals incorporating reversible, low molecular weight albumin binders
Brandt, M., Cardinale, J., Giammei, C., Guarrochena, X., Happl, B., Jouini, N. & Mindt, T. L.
Nuclear Medicine and Biology (2019) 70, 46-52